Direct suppression of TCR-mediated activation of extracellular signal- regulated kinase by leukocyte protein tyrosine phosphatase, a tyrosine- specific phosphatase

Journal of Immunology

Volumn 163, Issue 3, 1999, Pages 1282-1288

  Oh Hora, Masatsugu ^a   Ogata, Masato ^a   Mori, Yoshiko ^a   Adachi, Masaaki ^b   Imai, Kohzoh ^b   Kosugi, Atsushi ^a   Hamaoka, Toshiyuki ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CROSS LINKING; DEPHOSPHORYLATION; ENZYME BINDING; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; ENZYME ACTIVATION; GENETIC VECTORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; KIDNEY; MACROMOLECULAR SUBSTANCES; MAP KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; SHP1 PROTEIN TYROSINE PHOSPHATASE; TRANSFECTION; TYROSINE;

EID: 0033178615     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Wange, R. L., and L. E. Samelson. 1996. Complex complexes: signaling at the TCR. Immunity 5:197.
2. Qian, D., and A. Weiss. 1997. T cell antigen receptor signal transduction. Curr. Opin. Cell Biol. 9:205.
3. Tonks, N. K., and B. G. Neel. 1996. From form to function: signaling by protein tyrosine phosphatases. Cell 87:365.
4. Tonks, N. K. 1996. Protein tyrosine phosphatases and the control of cellular signaling responses. Adv. Pharmacol. 36:91.
5. Neel, B. G., and N. K. Tonks. 1997. Protein tyrosine phosphatases in signal transduction. Curr. Opin. Cell Biol. 9:193.
6. Adachi, M., M. Sekiya, M. Isobe, Y. Kumura, Z. Ogita, Y. Hinoda, K. Imai, and A. Yachi. 1992. Molecular cloning and chromosomal mapping of a human protein-tyrosine phosphatase LC-PTP. Biochem. Biophys. Res. Commun. 186:1607.
7. Zanke, B., H. Suzuki, K. Kishihara, L. Mizzen, M. Minden, A. Pawson, and T. W. Mak. 1992. Cloning and expression of an inducible lymphoid-specific, protein tyrosine phosphatase (HePTPase). Eur. J. Immunol. 22:235.
8. Saxena, M., S. Williams, J. Gilman, and T. Mustelin. 1998. Negative regulation of T cell antigen receptor signal transduction by hematopoietic tyrosine phosphatase (HePTP). J. Biol. Chem. 273:15340.
9. Sun, H., C. H. Charles, L. F. Lau, and N. K. Tonks. 1993. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 75:487.
10. Ward, Y., S. Gupta, P. Jensen, M. Wartmann, R. J. Davis, and K. Kelly. 1994. Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1. Nature 367:651.
11. Keyse, S. M. 1995. An emerging family of dual specificity MAP kinase phosphatases. Biochim. Biophys. Acta 1265:152.
12. Keyse, S. M. 1998. Protein phosphatases and the regulation of MAP kinase activity. Semin. Cell Dev. Biol.9:143.
13. ras distinguishes positive and negative selection in thymocytes. EMBO J. 14:276.
14. Alberola-Ila, J., K. A. Forbush, R. Seger, E. G. Krebs, and R. M. Perlmutter. 1995. Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 373:620.
15. Alberola-Ila, J., K. A. Hogquist, K. A. Swan, M. J. Bevan, and R. M. Perlmutter. 1996. Positive and negative selection invoke distinct signaling pathways. J. Exp. Med. 184:9.
16. O'Shea, C. C., T. Crompton, I. R. Rosewell, A. C. Hayday, and M. J Owen. 1996. Raf regulates positive selection. Eur. J. Immunol. 26:2350.
17. Shao, H., E. M. Rubin, L. Y. Chen, and J. Kaye. 1997. A role for Ras signaling in coreceptor regulation during differentiation of a double-positive thymocyte cell line. J. Immunol. 159:5773.
18. Sharp, L. L., D. A. Schwarz, C. M. Bott, C. J. Marshall, and S. M. Hedrick. 1997. The influence of the MAPK pathway on T cell lineage commitment. Immunity 7:609.
19. Sugawara, T., T. Moriguchi, E. Nishida, and Y. Takahama. 1998. Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes. Immunity 9:565.
20. Brunner, D., N. Oellers, J. Szabad, W. 3. Biggs, S. L. Zipursky, and E. Hafen. 1994. A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways. Cell 76:875.
21. Mizushima, S., and S. Nagata. 1990. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18:5322.
22. Northrop, J. P., K. S. Ullman, and G. R. Crabtree. 1993. Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex. J. Biol. Chem. 268:2917.
23. Ogata, M., M. Sawada, Y. Fujino, and T. Hamaoka. 1995. cDNA cloning and characterization of a novel receptor-type protein tyrosine phosphatase expressed predominantly in the brain. J. Biol. Chem. 270:2337.
24. Mansour, S. J., W. T. Matten, A. S. Hermann, J. M. Candia, S. Rong, K. Fukasawa, G. F. Vande Woude, and N. G. Ahn. 1994. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265:966.
25. Cowley, S., H. Paterson, P. Kemp, and C. J. Marshall. 1994. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77:841.
26. Raingeaud, J., A. J. Whitmarsh, T. Barrett, B. Derijard, and R. J. Davis. 1996. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol. Cell. Biol. 16:1247.
27. Hendriks, W., J. Schepens, C. Brugman, P. Zeeuwen, and B. Wieringa. 1995. A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain. Biochem. J. 305:499.
28. Sharma, E., and P. J. Lombroso. 1995. A neuronal protein tyrosine phosphatase induced by nerve growth factor. J. Biol. Chem. 270:49.
29. Shiozuka, K., Y. Watanabe, T. Ikeda, S. Hashimoto, and H. Kawashima. 1995. Cloning and expression of PCPTP1 encoding protein tyrosine phosphatase. Gene 162:279.
30. Ogata, M., M. Oh-hora, A. Kosugi, and T. Hamaoka. 1999. Inactivation of mitogen-activated protein kinases by a mammalian tyrosine-specific phosphatase, PTPBR7. Biochem. Biophys. Res. Commun. 256:52.
31. Pulido, R., Á. Zùñiga, and A. Ullich. 1998. PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif. EMBO J. 24:7337.
32. Swieter, M., E. H. Berenstein, W. D. Swaim, and R. P. Siraganian. 1995. Aggregation of IgE receptors in rat basophilic leukemia 2H3 cells induces tyrosine phosphorylation of the cytosolic protein-tyrosine phosphatase HePTP. J. Biol. Chem. 270:21902.
33. Bult, A., F. Zhao, R. Dirkx, Jr., E. Sharma, E. Lukacsi, M. Solimena, J. R. Naegele, and P. J. Lombroso. 1996. STEP61: a member of a family of brain-enriched PTPs is localized to the endoplasmic reticulum. J. Neurosci. 16: 7821.
34. Lombroso, P. J., G. Murdoch, and M. Lerner. 1991 Molecular characterization of a protein-tyrosine-phosphatase enriched in striatum. Proc. Natl. Acad. Sci. USA 88:7242.
35. Wurgler-Murphy, S. M., T. Maeda, E. A. Witten, and H. Saito. 1997. Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases. Mol. Cell. Biol. 17:1289.
36. Adachi, M., M. Sekiya, M. Ishino, H. Sasaki, Y. Hinoda, K. Imai, and A. Yachi. 1994. Induction of protein-tyrosine phosphatase LC-PTP by IL-2 in human T cells. LC-PTP is an early response gene. FEBS Lett. 338:47.
37. Adachi, M., T. Torigoe, M. Sekiya, Y. Minami, T. Taniguchi, Y. Hinoda, A. Yachi, J. C. Reed, and K. Imai. 1995. IL-2-induced gene expression of protein-tyrosine phosphatase LC-PTP requires acidic and serine-rich regions within IL-2 receptor β chain. FEBS Lett. 372:113.
38. Bott, C. M., S. G. Thorneycroft, and C. J. Marshall. 1994. The sevenmaker gain-of-function mutation in p42 MAP kinase leads to enhanced signaling and reduced sensitivity to dual specificity phosphatase action. FEBS Lett. 352:201.
39. Chu, Y., P. A. Solski, R. Khosravi-Far, C. J. Der, and K. Kelly. 1996. The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation. J. Biol. Chem. 271:6497.
40. Camps, M., A. Nichols, C. Gillieron, B. Antonsson, M. Muda, C. Chabert, U. Boschert, and S. Arkinstall. 1998. Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase. Science 280:1262.