Hematopoietic protein tyrosine phosphatase suppresses extracellular stimulus-regulated kinase activation

Molecular and Cellular Biology

Volumn 21, Issue 20, 2001, Pages 6851-6858

  Gronda, M ^a   Arab, S ^a   Iafrate, B ^a   Suzuki, H ^a   Zanke, B W ^a  

^a CROSS CANCER INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL LINEAGE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ANALYSIS; GENE CONSTRUCT; GENE DELETION; GENETIC RECOMBINATION; HEMATOPOIESIS; LYMPHOCYTE ACTIVATION; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD3; BINDING SITES; CELL DIVISION; CELL LINEAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE DELETION; HEMATOPOIETIC STEM CELLS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, GENETIC; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, ANTIGEN, T-CELL; RECOMBINATION, GENETIC; SHP1 PROTEIN TYROSINE PHOSPHATASE; TH1 CELLS; TH2 CELLS; TIME FACTORS;

EID: 0034802515     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.20.6851-6858.2001     Document Type: Article

References (44)

1. IL-2-induced gene expression of protein-tyrosine phosphatase LC-PTP requires acidic and serine-rich regions within IL-2 receptor beta chain
2. Growth factor-stimulated phosphorylation cascades: Activation of growth factor-stimulated MAPK
3. The human p50csk tyrosine kinase phosphorylates p561ck at Tyr-505 and down regulates its catalytic activity
4. Induction of mitogen-activated protein kinase phosphatase 1 by the stress-activated protein kinase signaling pathway but not by extracellular signal-regulated kinase in fibroblasts
5. Regulation of CD69 expression on human natural killer cells: Differential involvement of protein kinase C and protein tyrosine kinases
6. Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase
7. The mitogen-activated protein kinase phosphatases PAC1: MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation
8. The mitogen-activated protein kinase signal transduction pathway
9. Disruption of the ERP/MKP-1 gene does not affect mouse development: Normal MAPK activity in ERP/MKP-1-deficient fibroblasts
10. Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells
11. An osmosensing signal transduction pathway in mammalian cells
12. An analysis of Mek1 signaling in cell proliferation and transformation
13. The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
14. Detection of gene amplification by genomic hybridization to cDNA microarrays
15. Widespread aneuploidy revealed by DNA microarray expression profiling
16. Structure-function studies of p38 mitogen-activated protein kinase. Loop 12 influences substrate specificity and autophosphorylation, but not upstream kinase selection
17. An emerging family of dual specificity MAPK phosphatases
18. Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice
19. The stress-activated protein kinase subfamily of c-Jun kinases
20. A divergence in the MAPK regulatory network defined by MEK kinase and Raf
21. Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAPK controlling cell size at division in fission yeast
22. Cyclin-dependent kinases: Engines, clocks, and microprocessors
23. MKP-3: A novel cytosolic protein tyrosine phosphatase that exemplifies a new class of mitogen activated protein kinase phosphatase
24. Molecular cloning and functional characterization of a novel mitogen-activated protein kinase phosphatase, MKP-4
25. The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen-activated protein kinases
26. Rapid activation of the T-cell tyrosine protein kinase pp561ck by the CD45 phosphotyrosine phosphatase
27. Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAPK)
28. Requirements for phosphorylation of MAPK during meiosis in Xenopus oocytes
29. PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif
30. Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles
31. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
32. Negative regulation of T cell antigen receptor signal transduction by hematopoietic tyrosine phosphatase (HePTP)
33. The MAPK signaling cascade
34. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAPK in vivo
35. Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1
36. Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor
37. Ras-dependent activation of c-Jun N-terminal kinase/stress-activated protein kinase in response to interleukin-3 stimulation in hematopoietic BaF3 cells
38. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
39. Phenotypic analysis of murine long-term hemopoietic reconstituting cells quantitated competitively in vivo and comparison with more advanced colony-forming progeny
40. Control of MAPK activation by the mitogen-induced threonine/tyrosine phosphatase PAC1
41. Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases
42. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
43. Insulation of mammalian MAPK pathways through formation of specific kinase: Activator complexes
44. Cloning and expression of an inducible lymphoid-specific, protein tyrosine phosphatase (HePTPase)