TNF, TNF receptor type 1, and allograft inflammatory factor-1 gene polymorphisms in Japanese patients with type 1 diabetes

Human Immunology

Volumn 64, Issue 2, 2003, Pages 302-309

  Nishimura, Masataka ^a   Obayashi, Hiroshi ^b   Mizuta, Ikuko ^c   Hara, Hirokazu ^d   Adachi, Tetsuo ^d   Ohta, Mitsuhiro ^e   Tegoshi, Hisataka ^f   Fukui, Michiaki ^f   Hasegawa, Goji ^f   Shigeta, Hirofumi ^f   Kitagawa, Yoshihiro ^f   Nakano, Koji ^f   Kaji, Ryuji ^a   Nakamura, Naoto ^f  

^a TOKUSHIMA UNIVERSITY HOSPITAL   (Japan)

^b Microbiological Institute   (Japan)

^c UTANO NATIONAL HOSPITAL   (Japan)

^d GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^e KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^f KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Allograft inflammatory factor 1; Polymorphism; TNF receptor; Tumor necrosis factor; Type 1 diabetes

Indexed keywords

ALLOGRAFT INFLAMMATORY FACTOR 1; HLA ANTIGEN; HLA ANTIGEN CLASS 2; HLA ANTIGEN CLASS 3; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; GENE EXPRESSION; GENE FREQUENCY; GENE LOCUS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; JAPAN; JUVENILE DIABETES MELLITUS; MAJOR CLINICAL STUDY; MATURITY ONSET DIABETES MELLITUS; PRIORITY JOURNAL;

EID: 0037321976     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(02)00799-1     Document Type: Article

References (31)

1. Hanifi Moghaddam P, de Knijf P, Roep BO, Van der Auwera B, Naipal A, Gorus F, Schuit F, Giphart MJ, the Belgian Diabetes Registry: Genetic structure of IDDM1. Two separate regions in the major histocompatibility complex contribute to susceptibility or protection. Diabetes 47:263, 1998.
2. Lie BA, Todd JA, Pociot F, Nerup J, Akselsen HE, Joner G, Dahl-Jogensen K, Ronningen KS, Thorsby E, Undlien DE: The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene. Am J Hum Genet 64:793, 1999.
3. Monos DS, Kamoun M, Udalova IA, Csanky E, Cizman B, Turetskaya RL, Smirnova JB, Zharkov VG, Gasser D, Zmijewski CM, Spielman RS, Nedospasov SA: Genetic polymorphism of the human tumor necrosis factor region in insulin-dependent diabetes mellitus. Linkage disequilibrium of TNFab microsatellite alleles with HLA haplotypes. Hum Immunol 44:70, 1995.
4. Jacob CO, Fronek Z, Lewis GD, Koo M, Hansen JA, McDevitt HO: Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci USA 87:1233, 1990.
5. Ma JJ, Nishimura M, Mine H, Kuroki S, Nukina M, Ohta M, Saji H, Obayashi H, Kawakami H, Saida T, Uchiyama T: Genetic contribution of the tumor necrosis factor region in Guillain-Barré syndrome. Ann Neurol 44:815, 1998.
6. Obayashi H, Nakamura N, Fukui M, Tegoshi H, Fujii M, Ogata M, Hasegawa G, Shigeta H, Kitagawa Y, Nakano K, Kondo M, Fukui I, Maruya E, Saji H, Ohta M, Nishimura M: Influence of TNF microsatellite polymorphisms (TNFa) on age-at-onset of insulin-dependent diabetes mellitus. Hum Immunol 60:974, 1999.
7. Rabinovitch A: An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus. Diabetes Metab Rev 14:129, 1998.
8. Higuchi T, Seki N, Kamizono S, Yamada A, Kimura A, Kato H, Itoh K: Polymorphisms of the 5′-flanking region of the human tumor necrosis factor (TNF)-α gene in Japanese. Tissue Antigens 51:605, 1998.
9. Uglialoro AM, Turbay D, Pesavento PA, Delgado JC, McKenzie FE, Gribben JG, Hartl D, Yunis EJ, Goldfeld AE: Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-α gene promoter. Tissue Antigens 52:359, 1998.
10. Skoog T, van't Hooft FM, Kallin B, Jovinge S, Boquist S, Nilsson J, Eriksson P, Hamsten A: A common functional polymorphism (C-A substitution at position -863) in the promoter region of the tumor necrosis factor-α (TNF-α) gene associated with reduced circulating levels of TNF-α. Hum Mol Genet 8:1443, 1999.
11. Komata T, Tsuchiya N, Matsushita M, Hagiwara K, Tokunaga K: Association of tumor necrosis factor receptor 2 (TNFR2) polymorphism with susceptibility to systemic lupus erythematosus. Tissue Antigens 53:527, 1999.
12. Pitts SA, Olomolaiye OO, Elson CJ, Westacott CI, Bidwell JL: Identification of a rare BglII polymorphism in the promoter region of the human TNF receptor type I (p155) gene. Eur J Immunogenet 25:271, 1998.
13. Utans U, Arceci RJ, Yamashita Y, Russell ME: Cloning and characterization of allograft inflammatory factor-1: a novel macrophage factor identified in rat cardiac allografts with chronic rejection. J Clin Invest 95:2954, 1995.
14. Schluesener HJ, Seid K, Kretzschmar J, Meyermann R: Allograft-inflammatory factor-1 in rat experimental autoimmune encephalomyelitis, neuritis, and uveitis: expression by activated macrophages and microglial cells. Glia 24:244, 1998.
15. Chen Z-W, Ahren B, Östenson C-G, Cintra A, Bergman T, Moller C, Fuxe K, Mutt V, Jornvall H, Efendic S: Identification, isolation, and characterization of daintain (allograft inflammatory factor 1), a macrophage polypeptide with effects on insulin secretion and abundantly present in the pancreas of prediabetic BB rats. Proc Natl Acad Sci USA 94:13879, 1997.
16. Ohta M, Obayashi H, Takahashi K, Kitagawa Y, Nakano K, Matsuo S, Nishimura M, Itoh N, Ohta K: Radioimmunoprecipitation assay for glutamic acid decarboxylase antobodies evaluated clinically with sera from patients with insulin-dependent diabetes mellitus. Clin Chem 42:1975, 1996.
17. Fukui M, Nakano K, Nakamura N, Maruya E, Saji H, Obayashi H, Ohta K, Ohta M, Mori H, Kajiyama S, Wada S, Kida Y, Kosaka K, Deguchi M, Shigeta H, Kitagawa Y, Kondo M: HLA-DRB1 alleles contribute to determining the prognosis of Japanese diabetes mellitus positive for antibodies to glutamate decarboxylase. J Clin Immunol 18:89, 1998.
18. Iris F, Bougueleret L, Prieur S, Caterina D, Primas G, Perrot V, Jurka J, Rodriguez-Tome P, Claverie JM, Dausset J, et al: Dense Alu clustering and a potential new member of the NF kappa B family within a 90 kilobase HLA class III segment. Nature Genet 3:137, 1993.
19. Kato T, Honda M, Kuwata S, Juji T, Kunugi H, Nanko S, Fukuda M, Honda Y: Novel polymorphism in the promoter region of the tumor necrosis factor alpha gene: no association with narcolepsy. Am J Med Genet 88:301, 1999.
20. Messer G, Spengler U, Jung MC, Honold G, Blomer K, Pape GR, Riethmuller G, Weiss EH: Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-β gene correlates with a variant amino acid in position 26 and a reduced level of TNF-β production. J Exp Med 173:209, 1991.
21. Nakajima T, Jorde LB, Ishigami T, Umemura S, Emi M, Lalouel J-M, Inoue I: Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations. Am J Hum Genet 70:108, 2002.
22. Gruen JR, Weissman SM: Evolving view of the major histocompatibility complex. Blood 90:4252, 1997.
23. Hashimoto M, Nakamura N, Obayashi H, Kimura F, Moriwaki A, Hasegawa G, Shigeta H, Kitagawa Y, Nakano K, Kondo M, Ohta M, Nishimura M: Genetic contribution of the BAT2 gene microsatellite polymorphism to the age-at-onset of insulin-dependent diabetes mellitus. Hum Genet 105:197, 1999.
24. Weissensteiner Th, Lanchbury JS: TNFB polymorphisms characterize three lineages of TNF region microsatellite haplotypes. Immunogenet 47:6, 1997.
25. Whichelow CE, Hitman GA, Raafat I, Bottazzo GF, Sachs JA: The effect of TNF*B gene polymorphism on TNF-α and -β secretion levels in patients with insulin-dependent diabetes mellitus and healthy controls. Eur J Immunogenet 23:425, 1996.
26. Tartaglia LA, Pennica D, Goeddel DV: Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor. J Biol Chem 268:18542, 1993.
27. Peschon JJ, Torrance DS, Stocking KL, Glaccum MB, Otten C, Willis CR, Charrier K, Morrissey PJ, Ware CB, Mohler KM: TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation. J Immunol 160:943, 1998.
28. Bulló M, Garcia-Lorda P, Salas-Salvadó J: Plasma soluble tumor necrosis factor alpha receptors and leptin levels in normal-weight and obese women: effect of adiposity and diabetes. Eur J Endocrinol 146:325, 2002.
29. Fernandez-Real J-M, Lainez B, Vendrell J, Rigla M, Castro A, Peñarroja G, Broch M, Pérez A, Richart C, Engel P, Richard W: Shedding of TNFα receptors, blood pressure, and insulin sensitivity in type 2 diabetes mellitus. Am J Physiol Endocrinol Metab 282:E952, 2002.
30. Hamaguchi K, Kimura A, Seki N, Higuchi T, Yasunaga S, Takahashi M, Sasazuki T, Kusuda Y, Okeda T, Itoh K, Sakata T: Analysis of tumor necrosis factor-α promoter polymorphism in type 1 diabetes: HLA-B and -DRB1 alleles are primarily associated with the disease in Japanese. Tissue Antigens 55:10, 2000.
31. Svejgaard A, Ryder LP: HLA and disease associations: detecting the strongest association. Tissue Antigens 43:18, 1994.