Genetic contribution of the BAT2 gene microsatellite polymorphism to the age-at-onset of insulin-dependent diabetes mellitus

Human Genetics

Volumn 105, Issue 3, 1999, Pages 197-199

  Hashimoto, Masao ^a   Nakamura, Naoto ^a   Obayashi, Hiroshi ^a,b   Kimura, Fumiaki ^a   Moriwaki, Akira ^a   Hasegawa, Goji ^a   Shigeta, Hirofumi ^a   Kitagawa, Yoshihiro ^a   Nakano, Koji ^a   Kondo, Motoharu ^a   Ohta, Mitsuhiro ^c   Nishimura, Masataka ^c  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b Kyoto Microbiological Institute   (Japan)

^c UTANO NATIONAL HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; MICROSATELLITE DNA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ALLELE; ARTICLE; CHILD; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; ONSET AGE; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGE OF ONSET; ALLELES; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; DNA; FEMALE; GENE FREQUENCY; HLA-DR ANTIGENS; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; PROTEINS; SEQUENCE ANALYSIS, DNA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032873303     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390051089     Document Type: Article

References (6)

1. Fujisawa T, Ikegami H, Kawaguchi Y, Yamato E, Takekawa K, Nakagawa Y, Hamada Y, Ueda H, Shima K, Ogihara T (1995) Class I HLA is associated with age-at-onset of IDDM, while class II HLA confers susceptibility to IDDM. Diabetologia 38: 1493-1494
2. Gallagher G, Eskdale J, Miller S (1997) A highly polymorphic microsatellite marker in the human MHC class III region, close to the BAT2 gene. Immunogenetics 46:357-358
3. Hanifi Moghaddam P, Knijf P de, Roep BO, Van der Auwera B, Naipal A, Gorus F, Schuit F, Giphart MJ (1998) Genetic structure of IDDM 1: two separate regions in the major histocompatibility complex contribute to susceptibility or protection. Belgian Diabetes Registry. Diabetes 47:263-269
4. Iris FJ, Bougueleret L, Prieur S, Caterina D, Primas G, Perrot V, Jurka J, Rodriguez-Tome P, Claverie JM, Dausset J, Cohen D (1993) Dense Alu clustering and a potential new member of the NF kappa B family within a 90 kilobase HLA class III segment. Nat Genet 3:137-145
5. National Diabetes Data Group (1979) Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 28:1039-1057
6. Spies T, Blanck G, Bresnahan M, Sands J, Strominger JL (1989) A new cluster of genes within the humn major histocompatibility complex. Science 243:214-217