A microarray-based antibiotic screen identifies a regulatory role for supercoiling in the osmotic stress response of Escherichia coli

Genome Research

Volumn 13, Issue 2, 2003, Pages 206-215

  Cheung, Kevin J ^a   Badarinarayana, Vasudeo ^a   Selinger, Douglas W ^a   Janse, Daniel ^a   Church, George M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL DNA; CHLORAMPHENICOL; HYPERTONIC SOLUTION; NOVOBIOCIN; PEFLOXACIN; TRANSCRIPTION FACTOR; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); ESCHERICHIA COLI PROTEIN; POTASSIUM; SIGMA FACTOR; SIGMA FACTOR KATF PROTEIN, BACTERIA; SODIUM CHLORIDE;

ADAPTATION; ALGORITHM; ARTICLE; BACTERIAL GENE; BINDING SITE; CELL FUNCTION; CELL PROTECTION; CELL TRANSPORT; CLUSTER ANALYSIS; CONTROLLED STUDY; DNA MICROARRAY; DNA SUPERCOILING; ESCHERICHIA COLI; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; NONHUMAN; OSMOTIC STRESS; PRIORITY JOURNAL; REGULATORY MECHANISM; SCREENING TEST; STATISTICAL ANALYSIS; TRANSCRIPTION INITIATION; BACTERIAL GENOME; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; MECHANICAL STRESS; METABOLISM; METHODOLOGY; MULTIGENE FAMILY; OSMOTIC PRESSURE; PHYSIOLOGY; TEMPERATURE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CYTOPROTECTION; DNA GYRASE; DNA TOPOISOMERASES, TYPE I, BACTERIAL; DNA, BACTERIAL; DNA, SUPERHELICAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENOME, BACTERIAL; MULTIGENE FAMILY; NOVOBIOCIN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSMOTIC PRESSURE; PEFLOXACIN; POTASSIUM; SIGMA FACTOR; SODIUM CHLORIDE; STRESS, MECHANICAL; TEMPERATURE; TRANSCRIPTION, GENETIC;

EID: 0037316190     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: 10.1101/gr.401003     Document Type: Article

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