Spreading acidification and depression in the cerebellar cortex

Neuroscientist

Volumn 9, Issue 1, 2003, Pages 37-45

  Ebner, Timothy J ^a   Chen, Gang ^b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b NONE

Author keywords

Channelopathy; Episodic ataxia; Parallel fibers; Potassium channels; Purkinje cells; Spreading acidification

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL;

ATAXIA; CALCIUM SIGNALING; CEREBELLUM CORTEX; DEPOLARIZATION; EVOKED RESPONSE; EVOKED VISUAL RESPONSE; GEOMETRY; INFORMATION PROCESSING; INTERNEURON; MOLECULAR MECHANICS; NEUROTRANSMISSION; PATHOPHYSIOLOGY; PH; PRIORITY JOURNAL; PURKINJE CELL; REVIEW; SPREADING ACIDIFICATION AND DEPRESSION; SPREADING CORTICAL DEPRESSION;

ACIDOSIS; ANIMALS; ATAXIA; CEREBELLAR CORTEX; HUMANS; HYDROGEN-ION CONCENTRATION; POTASSIUM CHANNELS; PURKINJE CELLS; SPREADING CORTICAL DEPRESSION;

EID: 0037310734     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/1073858402239589     Document Type: Review

References (62)

1. Adelman JP, Bond CT, Pessia M, Maylie J. 1995. Episodic ataxia results from voltage-dependent potassium channels with altered functions. Neuron 15:1449-54.
2. Aitken PG, Tombaugh GC, Turner DA, Somjen GG. 1998. Similar propagation of SD and hypoxic SD-like depolarization in rat hippocampus recorded optically and electrically. J Neurophysiol 80:1514-21.
3. Bahar S, Fayuk D, Somjen GG, Aitken PG, Turner DA. 2000. Mitochondrial and intrinsic optical signals imaged during hypoxia and spreading depression in rat hippocampal slices. J Neurophysiol 84:311-24.
4. Bain PG, O'Brien MD, Keevil SF, Porter DA. 1992. Familial periodic cerebellar ataxia: a problem of cerebellar intracellular pH homeostasis. Ann Neurol 31:147-54.
5. Billinton A, Upton N, Bowery NG. 1999. GABA(B) receptor isoforms GBR1a and GBR1b, appear to be associated with pre- and post-synaptic elements respectively in rat and human cerebellum. Br J Pharmacol 126:1387-92.
6. Bloedel JR, Courville J. 1981. A review of cerebellar afferent systems. In: Brooks VB, editor. Handbook of physiology, Sect. 1, The nervous system, Vol. II. Motor control, Part 2. 1 ed. Baltimore: Williams and Wilkins. p 735-830.
7. Boitano S, Dirksen ER, Sanderson MJ. 1992. Intercellular propagation of calcium waves mediated by inositol trisphosphate. Science 258:292-5.
8. Boland LM, Price DL, Jackson KA. 1999. Episodic ataxia/myokymia mutations functionally expressed in the Shaker potassium channel. Neuroscience 91:1557-64.
9. Brandt T, Strupp M. 1997. Episodic ataxia type 1 and 2 (familial periodic ataxia/vertigo). Audiol Neurootol 2:373-83.
10. Bretschneider F, Wrisch A, Lehmann-Hom F, Grissmer S. 1999. Expression in mammalian cells and electrophysiological characterization of two mutant Kv1.1 channels causing episodic ataxia type 1 (EA-1). Eur J Neurosci 11:2403-12.
11. Browne DL, Gancher ST, Nutt JG, Brunt ER, Smith EA, Kramer P, Litt M. 1994. Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1. Nat Genet 8:136-40.
12. Chen G, Dunbar RL, Gao W, Ebner TJ. 2001. Role of calcium, glutamate neurotransmission, and nitric oxide in spreading acidification and depression in the cerebellar cortex. J Neurosci 21:9877-87.
13. Chen G, Dunbar RL, Gao W, Reinert K, Ebner TJ. 2002a. Role of Kv1.1 Potassium channels in spreading acidification: possible mechanism for cerebellar dysfunction in episodic ataxia type 1. Submitted.
14. Chen G, Dunbar RL, Gao W, Reinert K, Ebner TJ. 2002b. Role of Kv1.1 voltage gated potassium channel in cerebellar spreading acidification: possible link to episodic ataxia. Soc Neurosci Abstr.
15. Chen G, Hanson CL, Dunbar RL, Ebner TJ. 1999. Novel form of spreading acidification and depression in the cerebellar cortex demonstrated by neutral red optical imaging. J Neurophysiol 81:1992-8.
16. Chen G, Hanson CL, Ebner TJ. 1996. Functional parasagittal compartments in the rat cerebellar cortex: An in vivo optical imaging study using neutral red. J Neurophysiol 76:4169-74.
17. Chen G, Hanson CL, Ebner TJ. 1998. Optical responses evoked by cerebellar surface stimulation in vivo using neutral red. Neuroscience 84:645-68.
18. Chesler M, Kaila K. 1992. Modulation of pH by neuronal activity. Trends Neurosci 15:396-402.
19. Clark JD, Tempel BL. 1998. Hyperalgesia in mice lacking the Kv1.1 potassium channel gene. Neurosci Lett 251:121-4.
20. Comu S, Giuliani M, Narayanan V. 1996. Episodic ataxia and myokymia syndrome: a new mutation of potassium channel gene Kv1.1. Ann Neurol 40:684-7.
21. De Zeeuw CI, Simpson JI, Hoogenraad CC, Galjart N, Koekkoek SK, Ruigrok TJ. 1998. Microcircuitry and function of the inferior olive. Trends Neurosci 21:391-400.
22. Finkbeiner S. 1992. Calcium waves in astrocytes-filling in the gaps. Neuron 8:1101-8.
23. Gorelova NA, Koroleva VI, Amemori T, Pavlik V, Bures J. 1987. Ketamine blockade of cortical spreading depression in rats. Electroencephalogr Clin Neurohphysiol 66:440-7.
24. Guthrie PB, Knappenberger J, Segal M, Bennett MV, Charles AC, Kater SB. 1999. ATP released from astrocytes mediates glial calcium waves. J Neurosci 19:520-8.
25. Hanson CL, Chen G, Ebner TJ. 2000. Role of climbing fibers in determining the spatial patterns of activation in the cerebellar cortex to peripheral stimulation: an optical imaging study. Neuroscience 96:317-31.
26. Hawkes R, Herrup K. 1996. Aldolase C/Zebrin II and the regionalization of the cerebellum. J Mol Neurosci 6:147-58.
27. Hopkins WF. 1998. Toxin and subunit specificity of blocking affinity of three peptide toxins for heteromultimeric, voltage-gated potassium channels expressed in Xenopus oocytes. J Pharmacol Exp Ther 285:1051-60.
28. Ito M. 1984. The cerebellum and neural control. New York: Raven.
29. Jager H, Grissmer S. 2001. Regulation of a mammalian Shaker-related potassium channel, hKv1.5, by extracellular potassium and pH. FEBS Lett 488:45-50.
30. Kang J, Jiang L, Goldman SA, Nedergaard M. 1998. Astrocyte-mediated potentiation of inhibitory synaptic transmission. Nat Neurosci 1:683-92.
31. 2+ release in Bergmann glial cells in situ. J Neurosci 19:8401-8.
32. Kullmann DM, Rea R, Spauschus A, Jouvenceau A. 2001. The inherited episodic ataxias: how well do we understand the disease mechanisms? Neuroscientist 7:80-8.
33. Lang EJ, Sugihara I, Llinas R. 1996. GABAergic modulation of complex spike activity by the cerebellar nucleoolivary pathway in rat. J Neurophysiol 76:255-75.
34. Lauritzen M, Hansen AJ. 1992. The effect of glutamate receptor blockade on anoxic depolarization and cortical spreading depression. J Cereb Blood Flow Metab 12:223-9.
35. Lauritzen M, Nicholson C. 1988. The pathophysiology of classical migraine. In: Hopkins A, editor. Headache: problems in diagnosis management. London: MPN. p 79-109.
36. Leao AAP. 1944. Spreading depression of activity in the cerebral cortex. J Neurophysiol 7:359-90.
37. Lee SH, Kim WT, Cornell-Bell AH, Sontheimer H. 1994. Astrocytes exhibit regional specificity in gap-junction coupling. Glia 11:315-25.
38. Llinas R, Yarom Y. 1986. Oscillatory properties of guinea-pig inferior olivary neurones and their pharmacological modulation: an in vitro study. J Physiol 376:163-82.
39. Lubbers WJ, Brunt ER, Scheffer H, Litt M, Stulp R, Browne DL, van Weerden TW. 1995. Hereditary myokymia and paroxysmal ataxia linked to chromosome 12 is responsive to acetazolamide. J Neurol Neurosurg Psychtr 59:400-5.
40. Martins-Ferreira H, Nedergaard M, Nicholson C. 2000. Perspectives on spreading depression. Brain Res Rev 32:215-34.
41. Momose-Sato Y, Sato K, Mochida H, Yazawa I, Sasaki S, Kamino K. 2001. Spreading depolarization waves triggered by vagal stimulation in the embryonic chick brain: optical evidence for intercellular communication in the developing central nervous system. Neuroscience 102:245-62.
42. Muller T, Moller T, Neuhaus J, Kettenmann H. 1996. Electrical coupling among Bergmann glial cells and its modulation by glutamate receptor activation. Glia 17:274-84.
43. Newman EA. 2001. Propagation of intercellular calcium waves in retinal astrocytes and Muller cells. J Neurosci 21:2215-23.
44. Newman EA, Zahs KR. 1997. Calcium waves in retinal glial cells. Science 275:844-7.
45. 2+ channel gene CACNL1A4. Cell 87:543-52.
46. Parpura V, Basarsky TA, Liu F, Jeftinija K, Jeftinija S, Haydon PG. 1994. Glutamate-mediated astrocyte-neuron signalling. Nature 369:744-7.
47. Rutecki PA. 1992. Neuronal excitability: voltage-dependent currents and synaptic transmission. J Clin Neurophysiol 9:195-211.
48. Sappey-Marinier D, Vighetto A, Peyron R, Broussolle E, Bonmartin A. 1999. Phosphorus and proton magnetic resonance spectroscopy in episodic ataxia type 2. Ann Neurol 46:256-9.
49. Scheffer H, Brunt ER, Mol GJ, van d V, Stulp RP, Verlind E, and others. 1998. Three novel KCNA1 mutations in episodic ataxia type I families. Hum Genet 102:464-6.
50. Schreurs BG, Sanchez-Andres JV, Alkon DL. 1992. GABA-induced responses in Purkinje cell dendrites of the rabbit cerebellar slice. Brain Res 597:99-107.
51. Smart SL, Lopantsev V, Zhang CL, Robbins CA, Wang H, Chiu SY, and others. 1998. Deletion of the Kv1.1 potassium channel causes epilepsy in mice. Neuron 20:809-19.
52. Somjen GG. 2001. Mechanisms of spreading depression and hypoxic spreading depression-like depolarization. Physiol Rev 81:1065-96.
53. Somjen GG, Aitken PG, Czeh GL, Herreras O, Jing J, Young JN. 1992. Mechanism of spreading depression: a review of recent findings and a hypothesis. Can J Physiol Pharmacol 70(Suppl):S248-54.
54. + channel blockers. Br J Pharmacol 125:1375-81.
55. + currents in cerebellar basket and purkinje cells: Kv1 and Kv3 channel subfamilies are present in basket cell nerve terminals. J Neurosci 20:114-22.
56. Steidl JV, Yool AJ. 1999. Differential sensitivity of voltage-gated potassium channels Kv1.5 and Kv1.2 to acidic pH and molecular identification of pH sensor. Mol Pharmacol 55:812-20.
57. Tobiasz C, Nicholson C. 1982. Tetrodotoxin resistant propagation and extracellular sodium changes during spreading depression in rat cerebellum. Brain Res 241:329-33.
58. Veh RW, Lichtinghagen R, Sewing S, Wunder F, Grumbach IM, Pongs O. 1995. Immunohistochemical localization of five members of the Kv1 channel subunits: contrasting subcellular locations and neuron-specific co-localizations in rat brain. Eur J Neurosci 7:2189-205.
59. Wang H, Kunkel DD, Schwartzkroin PA, Tempel BL. 1994. Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain. J Neurosci 14:4588-99.
60. Welsh JP, Lang EJ, Sugihara I, Llinas R. 1995. Dynamic organization of motor control within the olivocerebellar system. Nature 374:453-7.
61. Zhang CL, Messing A, Chiu SY. 1999. Specific alteration of spontaneous GABAergic inhibition in cerebellar purkinje cells in mice lacking the potassium channel Kv1.1. J Neurosci 19:2852-64.
62. Zhou L, Zhang CL, Messing A, Chiu SY. 1998. Temperature-sensitive neuromuscular transmission in Kv1. 1 null mice: role of potassium channels under the myelin sheath in young nerves. J Neurosci 18:7200-15.