Differential sensitivity of voltage-gated potassium channels Kv1.5 and Kv1.2 to acidic pH and molecular identification of pH sensor

Molecular Pharmacology

Volumn 55, Issue 5, 1999, Pages 812-820

  Steidl, Jill V ^a   Yool, Andrea J ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL;

ACIDIFICATION; ALKALINIZATION; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; ANIMALS; HISTIDINE; HYDROGEN-ION CONCENTRATION; KV1.2 POTASSIUM CHANNEL; KV1.5 POTASSIUM CHANNEL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OOCYTES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; SEQUENCE HOMOLOGY, AMINO ACID; XENOPUS LAEVIS;

EID: 0032946237     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Ahn D-S and Hume JR (1997) pH regulation of voltage-dependent K+ channels in canine arterial smooth muscle cells. Eur J Phys 433:758-765.
2. + channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary arterial myocytes. J Clin Invest 101:2319-2330.
3. Axford TC, Dearani JA, Khait I, Park WM, Patel MA, Doursounian M, Neuringer L, Valeri CE and Khuri SF (1992) Electrode-derived myocardial pH measurements reflect intracellular myocardial metabolism assessed by phosphorus 31-nuclear magnetic resonance spectroscopy during normothermic ischemia. J Thorac Cardiovasc Surg 103:902-907.
4. + channels? Circ Res 77:361-369.
5. Barry DM and Nerbonne JM (1996) Myocardial potassium channels: Electrophysiology and molecular diversity. Annu Rev Physiol 58:363-394.
6. Bergofsky EH, Lehr DE and Fishman AP (1962) The effect of changes in hydrogen ion concentration on the pulmonary circulation. J Clin Invest 41:1492-1502.
7. Bethell HWL, Vandenberg JI, Smith GA and Grace AA (1998) Changes in ventricular repolarization during acidosis and low-flow ischemia. Am J Physiol 275: H551-H560.
8. Busch AE, Hurst RS, North RA, Adelman JP and Kavanaugh MP (1991) Current inactivation involves a histidine residue in the pore of the rat lymphocyte potassium channel RGK5. Biochem Biophys Res Comm 179:1384-1390.
9. Carbone E, Fioravanti R, Prestipino G and Wanke E (1978) Action of extracellular pH on Na+ and K+ membrane currents in the giant axon of Loligo vulgaris. J Membr Biol 43:295-315.
10. Chandy KG, Williams CB, Spencer RH, Aguilar BA, Ghanshani S, Tempel BL and Gutman GA (1990) A family of three mouse potassium channel genes with intronless coding regions. Science 247:973-975.
11. Chesler M and Kaila K (1992) Modulation of pH by neuronal activity. Trends Neurosci 15:396-402.
12. Chung S, Joe J, Soh H, Lee M-Y and Bang H-W (1998a) Delayed rectifier potassium currents induced in activated rat microglia set the resting membrane potential. Neurosci Lett 242:73-76.
13. Chung S, Lee M-Y, Soh H, Jung W and Joe E (1998b) Modulation of membrane potential by extracellular pH in activated microglia in rats. Neurosci Lett 249: 139-142.
14. Coraboeuf E, Deroubaix E and Hoerter J (1976) Control of ionic permeabilities in normal and ischemic heart. Circ Res 38(Supp 1):I92-I97.
15. Coulter KL, Périer F, Radeke CM and Vandenberg CA (1995) Identification and molecular localization of a pH sensing domain for the inward rectifier potassium channel HIR. Neuron 15:1157-1168.
16. Dixon JE and McKinnon D (1994) Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats. Circ Res 75:252-260.
17. Eder C (1998) Ion channels in microglia (brain macrophages). Am J Physiol 275: C327-C342.
18. Fakler B, Schultz JH, Yang J, Schulte U, Brandle U, Zenner HP and Jan LY (1996) Identification of a titratable lysine residue that determines sensitivity of kidney potassium channels (ROMK) to intracellular pH. EMBO J 15:4093-4099.
19. + current in cultured adult human atrial myocytes. Circ Res 80:572-579.
20. Fry CH and Poole-Wilson PA (1981) Effects of acid-base changes on excitation-contraction coupling in guinea-pig and rabbit cardiac ventricular muscle. J Physiol (Lond) 313:141-160.
21. Hecht HH and Hutter OF (1965) Action of pH on cardiac Purkinje fibres, in Electrophysiology of the Heart (Taccardi B and Marchetti G eds) pp 105-123, Pergamon Press, Oxford.
22. Hille B (1968) Charges and potentials at the nerve surface: Divalent ions and pH. J Gen Physiol 51:221-235.
23. + currents expressed in Xenopus oocytes by mKv1.1 and mKv1.2 and their heteromultimers as revealed by mutagenesis of the dendrotoxin-binding site in mKv1.1. Pflügers Arch 428:382-390.
24. + channels: Effects of alterations in the carboxy-terminal region. Neuron 7:547-556.
25. + uptake channels. Proc Natl Acad Sci 94:4806-4810.
26. Jou I, Chung S, Jung SY, Gwag BJ and Joe EH (1998) Expression of Kv1.5 K+ channels in activated microglia in vivo. Glia 24:408-414.
27. López-Barneo J, Hoshi T, Heinemann SH and Aldrich RW (1993) Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors Channels 1:61-71.
28. Matsubara H, Suzuki J and Inada M (1993) Shaker-related potassium channel, Kv1.4, mRNA regulation in cultured rat heart myocytes and differential expression of Kv1.4 and Kv1.5 genes in myocardial development and hypertrophy. J Clin Invest 92:1659-1666.
29. + channel protein in explanted cardiac tissue. J Clin Invest 96:282-292.
30. Orchard CH and Cingolani HE (1994) Acidosis and arrhythmias in cardiac muscle. Cardiovasc Res 28:1312-1319.
31. + channel from vascular and visceral smooth muscles. Am J Physiol 267:C1231-C1238.
32. Post JM, Hume JR, Archer SL and Weir EK (1992) Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction. Am J Physiol 262:C882-C890.
33. Rasmusson RL, Morales MJ, Wang S, Liu S, Campbell DL, Brahmajothi MV and Strauss HC (1998) Inactivation of voltage-gated potassium channels. Circ Res 82:739-750.
34. Roden DM and George AL (1997) Structure and function of cardiac sodium and potassium channels. Am J Physiol 273:H511-H525.
35. Sherwood, L (1997) Human Physiology: From Cells to Systems, 3rd ed, Wadsworth Publishing, Belmont, CA.
36. Swanson R, Marshall J, Smith JS, Williams JB, Boyle MB, Folander K, Luneau CJ, Antanavage J, Oliva C, Buhrow SA, Bennett C, Stein RB and Kaczmarek LK (1990) Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain. Neuron 4:929-939.
37. Vaughan Williams EM and Whyte JM (1967) Chemosensitivity of cardiac muscle. J Physiol (Lond) 189:119-137.
38. + current densities and Kv1.5 expression are reduced in chronic human atrial fibrillation. Circ Res 80:772-781.
39. Yan G-X and Kléber AG (1992) Changes in extracellular and intracellular pH in ischemic rabbit papillary muscle. Circ Res 71:460-470.
40. + channels in pulmonary arterial smooth muscle cells. Am J Physiol 274:L621-L635.