메뉴 건너뛰기




Volumn 73, Issue 2, 2003, Pages 297-305

The improved survival of hematopoietic cells cultured with a fusion protein of insulin-like growth factor II (IGF-II) and interleukin 3 (IL-3) is associated with increases in Bcl-xL and phosphatidylinositol-3 kinase activity

Author keywords

CD34; Stat5

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; HYBRID PROTEIN; INTERLEUKIN 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROPIDIUM IODIDE; PROTEIN BCL XL; RECOMBINANT PROTEIN; SOMATOMEDIN B; STAT5 PROTEIN;

EID: 0037310077     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0802396     Document Type: Article
Times cited : (6)

References (41)
  • 1
    • 0029100655 scopus 로고
    • Hematopoietic stem cell cytokine response
    • Lowry, P. A. (1995) Hematopoietic stem cell cytokine response. J. Cell. Biochem. 58, 410-415.
    • (1995) J. Cell. Biochem. , vol.58 , pp. 410-415
    • Lowry, P.A.1
  • 2
    • 0028204469 scopus 로고
    • Accurate processing and secretion in the baculovirus expression system of an erythroid-cell-stimulating factor consisting of a chimaera of insulin-like growth factor II and an insect insulin-like peptide
    • Congote, L. F., Li, Q. (1994) Accurate processing and secretion in the baculovirus expression system of an erythroid-cell-stimulating factor consisting of a chimaera of insulin-like growth factor II and an insect insulin-like peptide. Biochem. J. 299, 101-107.
    • (1994) Biochem. J. , vol.299 , pp. 101-107
    • Congote, L.F.1    Li, Q.2
  • 3
    • 0030869149 scopus 로고    scopus 로고
    • Preparation of a recombinant chimera of insulin-like growth factor II and interleukin 3 with high proliferative potency for hematopoietic cells
    • DiFalco, M. R., Congote, L. F. (1997) Preparation of a recombinant chimera of insulin-like growth factor II and interleukin 3 with high proliferative potency for hematopoietic cells. Biochem. J. 326, 407-413.
    • (1997) Biochem. J. , vol.326 , pp. 407-413
    • DiFalco, M.R.1    Congote, L.F.2
  • 5
    • 0027320668 scopus 로고
    • Apoptosis of human erythroid colony-forming cells is decreased by stem cell factor and insulin-like growth factor I as well as erythropoietin
    • Muta, K., Krantz, S. B. (1993) Apoptosis of human erythroid colony-forming cells is decreased by stem cell factor and insulin-like growth factor I as well as erythropoietin. J. Cell. Physiol. 156, 264-271.
    • (1993) J. Cell. Physiol. , vol.156 , pp. 264-271
    • Muta, K.1    Krantz, S.B.2
  • 6
    • 0028326056 scopus 로고
    • Effects of interleukin-3 and c-kit ligand on the survival of various classes of human hematopoietic progenitor cells
    • Brandt, J. E., Bhalla, K., Hoffman, R. (1994) Effects of interleukin-3 and c-kit ligand on the survival of various classes of human hematopoietic progenitor cells. Blood 83, 1507-1514.
    • (1994) Blood , vol.83 , pp. 1507-1514
    • Brandt, J.E.1    Bhalla, K.2    Hoffman, R.3
  • 7
    • 0027523461 scopus 로고
    • Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforoed Bcl-2 oncoprotein production. IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line
    • Baffy, G., Miyashita, T., Williamson, J. R., Reed, J. C. (1993) Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforoed Bcl-2 oncoprotein production. IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line. J. Biol. Chem. 268, 6511-6519.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6511-6519
    • Baffy, G.1    Miyashita, T.2    Williamson, J.R.3    Reed, J.C.4
  • 9
    • 0030026693 scopus 로고    scopus 로고
    • Requirement for phosphatidylinositol 3′-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor
    • Minshall, C., Arkins, S., Freund, G. G., Kelley, K. W. (1996) Requirement for phosphatidylinositol 3′-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor. J. Immunol. 156, 939-947.
    • (1996) J. Immunol. , vol.156 , pp. 939-947
    • Minshall, C.1    Arkins, S.2    Freund, G.G.3    Kelley, K.W.4
  • 10
    • 0031047044 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 inhibition of apoptosis is associated with increased expression of the bcl-xL gene product
    • Parrizas, M., LeRoith, D. (1997) Insulin-like growth factor-1 inhibition of apoptosis is associated with increased expression of the bcl-xL gene product. Endocrinology 138, 1355-1358.
    • (1997) Endocrinology , vol.138 , pp. 1355-1358
    • Parrizas, M.1    LeRoith, D.2
  • 11
    • 0036020272 scopus 로고    scopus 로고
    • Antagonism between interleukin 3 and erythropoietin in mice with azidothymidine-induced anemia and in bone marrow endothelial cells
    • DiFalco, M. R., Congote, L. F. (2002) Antagonism between interleukin 3 and erythropoietin in mice with azidothymidine-induced anemia and in bone marrow endothelial cells. Cytokine 18, 51-60.
    • (2002) Cytokine , vol.18 , pp. 51-60
    • DiFalco, M.R.1    Congote, L.F.2
  • 12
    • 0037163109 scopus 로고    scopus 로고
    • Prolactin induces SHP-2 association with Stat5, nuclear translocation, and binding to the beta-casein gene promoter in mammary cells
    • Chughtai, N., Schimchowitsch, S., Lebrun, J. J., Ali, S. (2002) Prolactin induces SHP-2 association with Stat5, nuclear translocation, and binding to the beta-casein gene promoter in mammary cells. J. Biol. Chem. 277, 31107-31114.
    • (2002) J. Biol. Chem. , vol.277 , pp. 31107-31114
    • Chughtai, N.1    Schimchowitsch, S.2    Lebrun, J.J.3    Ali, S.4
  • 13
    • 0037203577 scopus 로고    scopus 로고
    • Insect cell production of a secreted form of human alpha(1)-proteinase inhibitor as a bifunctional protein which inhibits neutrophil elastase and has growth factor-like activities
    • Curtis, H., Sandoval, C., Oblin, C., Difalco, M. R., Congote, L. F. (2002) Insect cell production of a secreted form of human alpha(1)-proteinase inhibitor as a bifunctional protein which inhibits neutrophil elastase and has growth factor-like activities. J. Biotechnol. 93, 35-44.
    • (2002) J. Biotechnol. , vol.93 , pp. 35-44
    • Curtis, H.1    Sandoval, C.2    Oblin, C.3    Difalco, M.R.4    Congote, L.F.5
  • 14
    • 0028850053 scopus 로고
    • Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase
    • Royal, I., Park, M. (1995) Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase. J. Biol. Chem. 270, 27780-27787.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27780-27787
    • Royal, I.1    Park, M.2
  • 15
    • 0028818459 scopus 로고
    • The insulin receptor substrate-1-related 4PS substrate but not the interleukin-2R gamma chain is involved in interleukin-13-mediated signal transduction
    • Wang, L. M., Michieli, P., Lie, W. R., Liu, F., Lee, C. C., Minty, A., Sun, X. J., Levine, A., White, M. F., Pierce, J. H. (1995) The insulin receptor substrate-1-related 4PS substrate but not the interleukin-2R gamma chain is involved in interleukin-13-mediated signal transduction. Blood 86, 4218-4227.
    • (1995) Blood , vol.86 , pp. 4218-4227
    • Wang, L.M.1    Michieli, P.2    Lie, W.R.3    Liu, F.4    Lee, C.C.5    Minty, A.6    Sun, X.J.7    Levine, A.8    White, M.F.9    Pierce, J.H.10
  • 17
    • 0036274761 scopus 로고    scopus 로고
    • Enhanced proliferative effects of a baculovirus-produced fusion protein of insulin-like growth factor and alpha(1)-proteinase inhibitor and improved anti-elastase activity of the inhibitor with glutamate at position 351
    • Sandoval, C., Curtis, H., Congote, L. F. (2002) Enhanced proliferative effects of a baculovirus-produced fusion protein of insulin-like growth factor and alpha(1)-proteinase inhibitor and improved anti-elastase activity of the inhibitor with glutamate at position 351. Protein Eng. 15, 413-418.
    • (2002) Protein Eng. , vol.15 , pp. 413-418
    • Sandoval, C.1    Curtis, H.2    Congote, L.F.3
  • 20
    • 0029118847 scopus 로고
    • In vivo biologic effects of PIXY321, a synthetic hybrid protein of recombinant human granulocyte-macrophage colony-stimulating factor and interleukin-3 in cancer patients with normal hematopoiesis: A phase I study
    • Vadhan-Raj, S., Broxmeyer, H. E., Andreeff, M., Bandres, J. C., Buescher, E. S., Benjamin, R. S., Papadopoulos, N. E., Burgess, A., Patel, S., Plager, C., et al. (1995) In vivo biologic effects of PIXY321, a synthetic hybrid protein of recombinant human granulocyte-macrophage colony-stimulating factor and interleukin-3 in cancer patients with normal hematopoiesis: a phase I study. Blood 86, 2098-2105.
    • (1995) Blood , vol.86 , pp. 2098-2105
    • Vadhan-Raj, S.1    Broxmeyer, H.E.2    Andreeff, M.3    Bandres, J.C.4    Buescher, E.S.5    Benjamin, R.S.6    Papadopoulos, N.E.7    Burgess, A.8    Patel, S.9    Plager, C.10
  • 21
    • 0032899808 scopus 로고    scopus 로고
    • Clinical scale expansion of cryopreserved small volume whole bone marrow aspirates produces sufficient cells for clinical use
    • Lundell, B. I., Mandalam, R. K., Smith, A. K. (1999) Clinical scale expansion of cryopreserved small volume whole bone marrow aspirates produces sufficient cells for clinical use. J. Hematother. 8, 115-127.
    • (1999) J. Hematother. , vol.8 , pp. 115-127
    • Lundell, B.I.1    Mandalam, R.K.2    Smith, A.K.3
  • 24
    • 0035074829 scopus 로고    scopus 로고
    • Bivalent binding and signaling characteristics of Leridistim, a novel chimeric dual agonist of interleukin-3 and granulocyte colony-stimulating factor receptors
    • Monahan, J. B., Hood, W. F., Welply, J. K., Shieb, J. J., Polazzi, J. O., Li, X. (2001) Bivalent binding and signaling characteristics of Leridistim, a novel chimeric dual agonist of interleukin-3 and granulocyte colony-stimulating factor receptors. Exp. Hematol. 29, 416-424.
    • (2001) Exp. Hematol. , vol.29 , pp. 416-424
    • Monahan, J.B.1    Hood, W.F.2    Welply, J.K.3    Shieb, J.J.4    Polazzi, J.O.5    Li, X.6
  • 26
    • 0028957113 scopus 로고
    • Molecular and cellular aspects of the insulin-like growth factor I receptor
    • LeRoith, D., Werner, H., Beitner-Johnson, D., Roberts Jr., C. T. (1995) Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr. Rev. 16, 143-163.
    • (1995) Endocr. Rev. , vol.16 , pp. 143-163
    • LeRoith, D.1    Werner, H.2    Beitner-Johnson, D.3    Roberts C.T., Jr.4
  • 27
    • 0028036698 scopus 로고
    • Insulin receptor substrate-1 mediates phosphatidylinositol 3′-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation
    • Myers, M. G., Grammer, T. C., Wang, L. M., Sun, X. J., Pierce, J. H., Blenis, J., White, M. F. (1994) Insulin receptor substrate-1 mediates phosphatidylinositol 3′-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation. J. Biol. Chem. 269, 28783-28789.
    • (1994) J. Biol. Chem. , vol.269 , pp. 28783-28789
    • Myers, M.G.1    Grammer, T.C.2    Wang, L.M.3    Sun, X.J.4    Pierce, J.H.5    Blenis, J.6    White, M.F.7
  • 29
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • del Peso, L., Gonzalez-Garcia, M., Page, C., Herrera, R., Nunez, G. (1997) Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278, 687-689.
    • (1997) Science , vol.278 , pp. 687-689
    • Del Peso, L.1    Gonzalez-Garcia, M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 30
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 1.4-3-3 not BCL-X(L)
    • Zha, J., Harada, H., Yang, E., Jockel, J., Korsmeyer, S. J. (1996) Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 1.4-3-3 not BCL-X(L). Cell 87, 619-628.
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5
  • 31
    • 0030863160 scopus 로고    scopus 로고
    • Raf/MAPK and rapamycin-sensitive pathways mediate the anti-apoptotic function of p21Ras in IL-3-dependent hematopoietic cells
    • Kinoshita, T., Shirouzu, M., Kamiya, A., Hashimoto, K., Yokoyama, S., Miyajima, A. (1997) Raf/MAPK and rapamycin-sensitive pathways mediate the anti-apoptotic function of p21Ras in IL-3-dependent hematopoietic cells. Oncogene 15, 619-627.
    • (1997) Oncogene , vol.15 , pp. 619-627
    • Kinoshita, T.1    Shirouzu, M.2    Kamiya, A.3    Hashimoto, K.4    Yokoyama, S.5    Miyajima, A.6
  • 32
    • 0030953788 scopus 로고    scopus 로고
    • The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells
    • Sakai, I., Kraft, A. S. (1997) The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells. J. Biol. Chem. 272, 12350-12358.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12350-12358
    • Sakai, I.1    Kraft, A.S.2
  • 33
    • 0033525525 scopus 로고    scopus 로고
    • Constitutive activation of JAK2 confers murine interleukin-3-independent survival and proliferation of BA/F3 cells
    • Liu, C. B., Itoh, T., Arai, K., Watanabe, S. (1999) Constitutive activation of JAK2 confers murine interleukin-3-independent survival and proliferation of BA/F3 cells. J. Biol. Chem. 274, 6342-6349.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6342-6349
    • Liu, C.B.1    Itoh, T.2    Arai, K.3    Watanabe, S.4
  • 34
    • 0029794641 scopus 로고    scopus 로고
    • Erythropoietin can promote erythroid progenitor survival by repressing apoptosis through Bcl-XL and Bcl-2
    • Silva, M., Grillot, D., Benito, A., Richard, C., Nunez, G., Fernandez-Luna, J. L. (1996) Erythropoietin can promote erythroid progenitor survival by repressing apoptosis through Bcl-XL and Bcl-2. Blood 88, 1576-1582.
    • (1996) Blood , vol.88 , pp. 1576-1582
    • Silva, M.1    Grillot, D.2    Benito, A.3    Richard, C.4    Nunez, G.5    Fernandez-Luna, J.L.6
  • 35
    • 0031034517 scopus 로고    scopus 로고
    • In bone marrow derived Baf-3 cells, inhibition of apoptosis by IL-3 is mediated by two independent pathways
    • Leverrier, Y., Thomas, J., Perkins, G. R., Mangeney, M., Collins, M. K., Marvel, J. (1997) In bone marrow derived Baf-3 cells, inhibition of apoptosis by IL-3 is mediated by two independent pathways. Oncogene 14, 425-430.
    • (1997) Oncogene , vol.14 , pp. 425-430
    • Leverrier, Y.1    Thomas, J.2    Perkins, G.R.3    Mangeney, M.4    Collins, M.K.5    Marvel, J.6
  • 37
    • 0033597715 scopus 로고    scopus 로고
    • Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/-mice: A direct role for Stat5 in Bel-X(L) induction
    • Socolovsky, M., Fallon, A. E., Wang, S., Brugnara, C., Lodish, H. F. (1999) Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/-mice: a direct role for Stat5 in Bel-X(L) induction. Cell 98, 181-191.
    • (1999) Cell , vol.98 , pp. 181-191
    • Socolovsky, M.1    Fallon, A.E.2    Wang, S.3    Brugnara, C.4    Lodish, H.F.5
  • 38
    • 0026070118 scopus 로고
    • Growth-promoting effects of insulin-like growth factor-1 (IGF-1) on hematopoietic cells: Overexpression of introduced IGF-1 receptor abrogates interleukin-3 dependency of murine factor-dependent cells by a ligand-dependent mechanism
    • McCubrey, J. A., Steelman, L. S., Mayo, M. W., Algate, P. A., Dellow, R. A., Kaleko, M. (1991) Growth-promoting effects of insulin-like growth factor-1 (IGF-1) on hematopoietic cells: overexpression of introduced IGF-1 receptor abrogates interleukin-3 dependency of murine factor-dependent cells by a ligand-dependent mechanism. Blood 78, 921-929.
    • (1991) Blood , vol.78 , pp. 921-929
    • McCubrey, J.A.1    Steelman, L.S.2    Mayo, M.W.3    Algate, P.A.4    Dellow, R.A.5    Kaleko, M.6
  • 39
    • 0037205748 scopus 로고    scopus 로고
    • Potentiation of hematopoietic cell migration with an IGF-interleukin-3 fusion protein
    • DiFalco, M. R., Congote, L. F. (2002) Potentiation of hematopoietic cell migration with an IGF-interleukin-3 fusion protein. FEBS Lett. 524, 149-153.
    • (2002) FEBS Lett. , vol.524 , pp. 149-153
    • DiFalco, M.R.1    Congote, L.F.2
  • 40
    • 0027303072 scopus 로고
    • Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226
    • Freund, G. G., Kulas, D. T., Mooney, R. A. (1993) Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226. J. Immunol. 151, 1811-1820.
    • (1993) J. Immunol. , vol.151 , pp. 1811-1820
    • Freund, G.G.1    Kulas, D.T.2    Mooney, R.A.3
  • 41
    • 0027992342 scopus 로고
    • Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins
    • Gold, M. R., Duronio, V., Saxena, S. P., Schrader, J. W., Aebersold, R. (1994) Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins. J. Biol. Chem. 269, 5403-5412.
    • (1994) J. Biol. Chem. , vol.269 , pp. 5403-5412
    • Gold, M.R.1    Duronio, V.2    Saxena, S.P.3    Schrader, J.W.4    Aebersold, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.