-
1
-
-
0036615832
-
Tamoxifen, raloxifene and the prevention of breast cancer
-
Bentrem DJ, Jordan VC. Tamoxifen, raloxifene and the prevention of breast cancer. Minerva Endocrinol 2002; 27:127-139. •• Authoritative review of the current clinical development of chemopreventive agents with detailed accounts of the clinical and biological properties of tamoxifen and raloxifene. Pertinent discussions about duration of therapy, side effects and cross resistance. Detailed list of references.
-
(2002)
Minerva Endocrinol
, vol.27
, pp. 127-139
-
-
Bentrem, D.J.1
Jordan, V.C.2
-
2
-
-
0015069359
-
A new anti-oestrogenic agent in late breast cancer: An early clinical appraisal of ICI 46474
-
Cole MP, Jones CTA, Todd IDH. A new anti-oestrogenic agent in late breast cancer: an early clinical appraisal of ICI 46474. Br J Cancer 1971; 25:270-275.
-
(1971)
Br J Cancer
, vol.25
, pp. 270-275
-
-
Cole, M.P.1
Jones, C.T.A.2
Todd, I.D.H.3
-
3
-
-
0015915672
-
Anti-oestrogenic therapy for breast cancer: A trial of tamoxifen at low dose levels
-
Ward HWC. Anti-oestrogenic therapy for breast cancer: a trial of tamoxifen at low dose levels. BMJ 1973; 1:13-15.
-
(1973)
BMJ
, vol.1
, pp. 13-15
-
-
Ward, H.W.C.1
-
4
-
-
0036232065
-
The evolution of tamoxifen therapy in breast cancer: Selective oestrogen-receptor modulators and downregulators
-
O'Regan RM, Jordan VC. The evolution of tamoxifen therapy in breast cancer: selective oestrogen-receptor modulators and downregulators. Lancet Oncol 2002; 3:207-214. •• Excellent account of the development of the SERM concept (with tamoxifen as the prototype) and the application of molecular technology in the design of newer agents for treatment and prevention of breast cancer with tissue specific effects and fewer unwanted side effects.
-
(2002)
Lancet Oncol
, vol.3
, pp. 207-214
-
-
O'Regan, R.M.1
Jordan, V.C.2
-
5
-
-
0029048753
-
Gynaecologic effects of tamoxifen and the association with endometrial carcinoma
-
Assikis VJ, Jordan VC. Gynaecologic effects of tamoxifen and the association with endometrial carcinoma. Int J Gynaecol Obstet 1995; 49:241-257.
-
(1995)
Int J Gynaecol Obstet
, vol.49
, pp. 241-257
-
-
Assikis, V.J.1
Jordan, V.C.2
-
6
-
-
0026585852
-
Effects of tamoxifen on bone mineral density in post-menopausal women with breast cancer
-
Love RR, Mazess RB, Barden HS, et al. Effects of tamoxifen on bone mineral density in post-menopausal women with breast cancer. N Engl J Med 1992; 326:852-856.
-
(1992)
N Engl J Med
, vol.326
, pp. 852-856
-
-
Love, R.R.1
Mazess, R.B.2
Barden, H.S.3
-
7
-
-
0028212970
-
Tamoxifen and bone metabolism in post-menopausal low-risk breast cancer patients: A randomised study
-
Kristensen B, Ejlertsen B, Dalgaard P, et al. Tamoxifen and bone metabolism in post-menopausal low-risk breast cancer patients: a randomised study. J Clin Oncol 1994; 12:992-997.
-
(1994)
J Clin Oncol
, vol.12
, pp. 992-997
-
-
Kristensen, B.1
Ejlertsen, B.2
Dalgaard, P.3
-
8
-
-
0025931791
-
Effects of tamoxifen on cardiovascular risk factors in post-menopausal women
-
Love RR, Wiebe DA, Newcomb PA, et al. Effects of tamoxifen on cardiovascular risk factors in post-menopausal women. Ann Intern Med 1991; 115:860-864.
-
(1991)
Ann Intern Med
, vol.115
, pp. 860-864
-
-
Love, R.R.1
Wiebe, D.A.2
Newcomb, P.A.3
-
9
-
-
0027401344
-
Association of hormone replacement therapy with various cardiovascular risk factors in post-menopausal women
-
Nabulsi AA, Folsom AR, White A, et al. Association of hormone replacement therapy with various cardiovascular risk factors in post-menopausal women. N Engl J Med 1993; 328:1069-1075.
-
(1993)
N Engl J Med
, vol.328
, pp. 1069-1075
-
-
Nabulsi, A.A.1
Folsom, A.R.2
White, A.3
-
10
-
-
0028264285
-
Sex hormones and lipoprotein metabolism
-
Sacks FM, Walsh. Sex hormones and lipoprotein metabolism. Curr Opin Lipidol 1994; 5:236-240.
-
(1994)
Curr Opin Lipidol
, vol.5
, pp. 236-240
-
-
Sacks, F.M.1
Walsh2
-
11
-
-
0001626384
-
Antitumour effect of the anti-oestrogen ICI 46,474 (tamoxifen) in the dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma model
-
Jordan VC. Antitumour effect of the anti-oestrogen ICI 46,474 (tamoxifen) in the dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma model. J Steroid Biochem 1974; 5:354.
-
(1974)
J Steroid Biochem
, vol.5
, pp. 354
-
-
Jordan, V.C.1
-
12
-
-
0017078344
-
Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata
-
Jordan VC. Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata. Eur J Cancer 1976; 12:419-425.
-
(1976)
Eur J Cancer
, vol.12
, pp. 419-425
-
-
Jordan, V.C.1
-
13
-
-
0017102124
-
The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long term tissue culture
-
Lippman ME, Bolan G, Hiff K. The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long term tissue culture. Cancer Res 1976; 36:4595-4601.
-
(1976)
Cancer Res
, vol.36
, pp. 4595-4601
-
-
Lippman, M.E.1
Bolan, G.2
Hiff, K.3
-
14
-
-
0023547257
-
Effects of antiestrogens on bone in castrated and intact female rats
-
Jordan VC, Phelps E, Lingren JU. Effects of antiestrogens on bone in castrated and intact female rats. Breast Cancer Res Treat 1987; 10:31-35.
-
(1987)
Breast Cancer Res Treat
, vol.10
, pp. 31-35
-
-
Jordan, V.C.1
Phelps, E.2
Lingren, J.U.3
-
15
-
-
0030579801
-
Cloning of a novel estrogen receptor expressed in rat prostate and ovary
-
Kuiper GG, Enmark E, Pelto-Huikko M, et al. Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Proc Natl Acad Sci U S A 1996; 93:5925-5930.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5925-5930
-
-
Kuiper, G.G.1
Enmark, E.2
Pelto-Huikko, M.3
-
16
-
-
0030801841
-
Differential ligand activation of estrogen receptors ER alpha and ER beta at AP-1 sites
-
Paech K, Webb P, Kuiper GG, et al. Differential ligand activation of estrogen receptors ER alpha and ER beta at AP-1 sites. Science 1997; 277:1508-1510.
-
(1997)
Science
, vol.277
, pp. 1508-1510
-
-
Paech, K.1
Webb, P.2
Kuiper, G.G.3
-
17
-
-
0035421182
-
Selective estrogen receptor modulation: A personal perspective
-
Jordan VC. Selective estrogen receptor modulation: a personal perspective. Cancer Res 2001; 61:5683-5687.
-
(2001)
Cancer Res
, vol.61
, pp. 5683-5687
-
-
Jordan, V.C.1
-
19
-
-
0030033913
-
Antiatherogenic effects of adjuvant antiestrogens: A randomised trial comparing the effects of tamoxifen and toremifene on plasma lipid levels in post-menopausal women with node positive breast cancer
-
Saarto T, Blomquist C, Enholm C. Antiatherogenic effects of adjuvant antiestrogens: a randomised trial comparing the effects of tamoxifen and toremifene on plasma lipid levels in post-menopausal women with node positive breast cancer. J Clin Oncol 1996; 14:429-433.
-
(1996)
J Clin Oncol
, vol.14
, pp. 429-433
-
-
Saarto, T.1
Blomquist, C.2
Enholm, C.3
-
20
-
-
0029096747
-
Cardiac and vascular morbidity in women receiving adjuvant tamoxifen for breast cancer in a randomised trial
-
McDonald CC, Alexander FE, Whyte BW, et al. Cardiac and vascular morbidity in women receiving adjuvant tamoxifen for breast cancer in a randomised trial . BMJ 1995; 311:977-980.
-
(1995)
BMJ
, vol.311
, pp. 977-980
-
-
McDonald, C.C.1
Alexander, F.E.2
Whyte, B.W.3
-
21
-
-
0032481412
-
Impairment of cognitive function in women receiving adjuvant treatment for high-risk breast cancer: High dose versus standard-dose chemotherapy
-
van Dam FS, Schagen SB, Muller MJ, et al. Impairment of cognitive function in women receiving adjuvant treatment for high-risk breast cancer: high dose versus standard-dose chemotherapy. J Natl Cancer Inst 1998; 90:210-218.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 210-218
-
-
Van Dam, F.S.1
Schagen, S.B.2
Muller, M.J.3
-
22
-
-
0037123338
-
The effects of tamoxifen and estrogen on brain metabolism in elderly women
-
Ernst T, Chang L, Cooray D, et al. The effects of tamoxifen and estrogen on brain metabolism in elderly women. J Natl Cancer Inst 2002; 94:592-597.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 592-597
-
-
Ernst, T.1
Chang, L.2
Cooray, D.3
-
23
-
-
0037019752
-
The effects of tamoxifen and estrogen on brain metabolism in elderly women
-
Benson JR. The effects of tamoxifen and estrogen on brain metabolism in elderly women. J Natl Cancer Inst 2002; 94:1336-1337.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1336-1337
-
-
Benson, J.R.1
-
24
-
-
0024506261
-
A randomised clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen receptor-positive tumors
-
Fisher B, Costantino J, Redmond C, et al. A randomised clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen receptor-positive tumors. N Engl J Med 1989; 320:479-484.
-
(1989)
N Engl J Med
, vol.320
, pp. 479-484
-
-
Fisher, B.1
Costantino, J.2
Redmond, C.3
-
25
-
-
0032537990
-
Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 study
-
Fisher B, Constantino JP, Wickerman DL, et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 study. J Natl Cancer Inst 1998; 90:1371-1388.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1371-1388
-
-
Fisher, B.1
Constantino, J.P.2
Wickerman, D.L.3
-
26
-
-
0032537396
-
Tamoxifen for early breast cancer: An overview of the randomised trials
-
Early Breast Cancer Trialists Collaborative Group. Tamoxifen for early breast cancer: an overview of the randomised trials. Lancet 1998; 351:1451-1461.
-
(1998)
Lancet
, vol.351
, pp. 1451-1461
-
-
-
27
-
-
33645827164
-
First results from the International Breast Cancer Intervention Study (IBIS-I): A randomized prevention trial
-
First results from the International Breast Cancer Intervention Study (IBIS-I): a randomized prevention trial. Lancet 360; 817:24. •• Important announcement on results of large chemoprevention trial with tamoxifen showing reduction in breast cancer risk with 18% projected mortality reduction at 10 years in high-risk women. Study emphasized that thromboembolic events (including pulmonary embolism) were a worrying aspect of tamoxifen therapy in the chemopreventive setting and questions whether the overall risk-benefit ratio justifies intervention.
-
Lancet
, vol.360
, Issue.817
, pp. 24
-
-
-
29
-
-
0031691806
-
Tamoxifen and benign endometrial lesions
-
De Muylder X, Neven P, van Belle Y. Tamoxifen and benign endometrial lesions. Eur J Cancer 1998; 34 (Suppl 4):S18-S19.
-
(1998)
Eur J Cancer
, vol.34
, Issue.SUPPL. 4
-
-
De Muylder, X.1
Neven, P.2
Van Belle, Y.3
-
30
-
-
0029978834
-
Lack of genotoxicity of tamoxifen in human endometrium
-
Carmichael PL, Ugwumadu AHN, Neven P, et al. Lack of genotoxicity of tamoxifen in human endometrium. Cancer Res 1996; 56:1475-1479.
-
(1996)
Cancer Res
, vol.56
, pp. 1475-1479
-
-
Carmichael, P.L.1
Ugwumadu, A.H.N.2
Neven, P.3
-
31
-
-
0030033914
-
Effect of tamoxifen on endometrial proliferation
-
Decensi A, Fontana V, Bruno S, et al. Effect of tamoxifen on endometrial proliferation. J Clin Oncol 1996; 14:434-440.
-
(1996)
J Clin Oncol
, vol.14
, pp. 434-440
-
-
Decensi, A.1
Fontana, V.2
Bruno, S.3
-
32
-
-
0034626064
-
Risk and prognosis of endometrial cancer after tamoxifen for breast cancer. Comprehensive Cancer Centres' ALERT Group: Assessment of liver and endometrial cancer risk following tamoxifen
-
Bergman L, Beelen MI, Gallee MP, et al. Risk and prognosis of endometrial cancer after tamoxifen for breast cancer. Comprehensive Cancer Centres' ALERT Group: assessment of liver and endometrial cancer risk following tamoxifen. Lancet 2000; 356:881-887.
-
(2000)
Lancet
, vol.356
, pp. 881-887
-
-
Bergman, L.1
Beelen, M.I.2
Gallee, M.P.3
-
33
-
-
0036010916
-
Hysteroscopic assessment of menopausal breast cancer patients taking tamoxifen: Is there a bias from the mode of endometrial sampling in estimating morbidity?
-
Garuti G, Grossi F, Cellani F, et al. Hysteroscopic assessment of menopausal breast cancer patients taking tamoxifen: is there a bias from the mode of endometrial sampling in estimating morbidity? Breast Cancer Res Treat 2002; 72:245-253.
-
(2002)
Breast Cancer Res Treat
, vol.72
, pp. 245-253
-
-
Garuti, G.1
Grossi, F.2
Cellani, F.3
-
34
-
-
0032984748
-
Investigation of endometrial abnormalities in asymptomatic women treated with tamoxifen and an evaluation of the role of endometrial screening
-
Love CD, Muir BB, Scrimgeaur JB, et al. Investigation of endometrial abnormalities in asymptomatic women treated with tamoxifen and an evaluation of the role of endometrial screening. J Clin Oncol 1999; 17:2050-2054.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2050-2054
-
-
Love, C.D.1
Muir, B.B.2
Scrimgeaur, J.B.3
-
35
-
-
0033964226
-
Guidelines for monitoring patients taking tamoxifen treatment
-
Neven P, Vernaeve H. Guidelines for monitoring patients taking tamoxifen treatment. Drug Saf 2000; 22:1-11.
-
(2000)
Drug Saf
, vol.22
, pp. 1-11
-
-
Neven, P.1
Vernaeve, H.2
-
36
-
-
0036189449
-
Tamoxifen-induced endometrial changes in postmenopausal women with breast carcinoma
-
Juneja M, Jose R, Kekre AN. Tamoxifen-induced endometrial changes in postmenopausal women with breast carcinoma. Int J Gynaecol Obstet 2002; 76:279-284.
-
(2002)
Int J Gynaecol Obstet
, vol.76
, pp. 279-284
-
-
Juneja, M.1
Jose, R.2
Kekre, A.N.3
-
37
-
-
0037050789
-
Endometrial disorders in 406 breast cancer patients on tamoxifen: The case for less intensive monitoring
-
Vosse M, Renard F, Coibion M, et al. Endometrial disorders in 406 breast cancer patients on tamoxifen: the case for less intensive monitoring. Eur J Obstet Gynaecol 2002; 101:58-63. • Study examining endometrial lesions in 406 postmenopausal patients receiving tamoxifen compared with a control group of 823 women. Polyps were the most common pathology and all five endometrial cancers occurred after 3 years of tamoxifen use. Recommends baseline assessment with annual clinical examination after 3 years and prompt investigation of abnormal bleeding. Good discussion emphasizing lack of consensus on surveillance and quoting American College of Obstetricians and Gynaecologists recommending screening procedures 'at discretion of gynaecologist'.
-
(2002)
Eur J Obstet Gynaecol
, vol.101
, pp. 58-63
-
-
Vosse, M.1
Renard, F.2
Coibion, M.3
-
38
-
-
0037157603
-
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial
-
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. Lancet 2002; 359:2131-2139. •• Long awaited preliminary results of the ATAC trial comparing anastrozole, tamoxifen or a combination thereof as adjuvant therapy in postmenopausal women with early breast cancer. Significant improvement in disease-free survival in anastrozole group, but no data yet on overall survival. Critical discussion on relative benefits of aromatase inhibitors over tamoxifen in adjuvant and chemopreventive setting, but conclusion that further follow up is necessary to make a full risk-benefit assessment.
-
(2002)
Lancet
, vol.359
, pp. 2131-2139
-
-
-
39
-
-
0037012336
-
Upstaging tamoxifen? New classes of drugs emerging for breast cancer
-
Twombly R. Upstaging tamoxifen? New classes of drugs emerging for breast cancer. J Natl Cancer Inst 2002; 94:474-475. • Succinct and topical commentary on current trends and progress in standard endocrine treatments for breast cancer with potential new agents including aromatase inhibitors, SERMs and pure antiestrogens.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 474-475
-
-
Twombly, R.1
-
40
-
-
0033575083
-
The effect of raloxifene on risk of breast cancer in post-menopausal women: Results from the MORE randomised trial
-
Cummings SR, Eckert S, Krueger KA, et al. The effect of raloxifene on risk of breast cancer in post-menopausal women: results from the MORE randomised trial. JAMA 1999; 281:2189-2197.
-
(1999)
JAMA
, vol.281
, pp. 2189-2197
-
-
Cummings, S.R.1
Eckert, S.2
Krueger, K.A.3
-
41
-
-
0037065599
-
Recruitment of women into clinical trials
-
Benson JR. Recruitment of women into clinical trials. Lancet 2002; 359:164-166.
-
(2002)
Lancet
, vol.359
, pp. 164-166
-
-
Benson, J.R.1
-
42
-
-
0023229345
-
The antitumor actions of keoxifene (raloxifene) and tamoxifen in the N-nitroso-N-methylurea induced rat mammary carcinoma model
-
Gottardis MM, Jordan VC. The antitumor actions of keoxifene (raloxifene) and tamoxifen in the N-nitroso-N-methylurea induced rat mammary carcinoma model. Cancer Res 1987; 47:4020-4024.
-
(1987)
Cancer Res
, vol.47
, pp. 4020-4024
-
-
Gottardis, M.M.1
Jordan, V.C.2
-
43
-
-
0034193122
-
Effects of high dose raloxifene in selected patients with advanced breast carcinoma
-
Gradishar W, Glusman J, Lu Y, et al. Effects of high dose raloxifene in selected patients with advanced breast carcinoma. Cancer 2000; 88:2047-2053.
-
(2000)
Cancer
, vol.88
, pp. 2047-2053
-
-
Gradishar, W.1
Glusman, J.2
Lu, Y.3
-
44
-
-
0037138745
-
Effects of raloxifene after tamoxifen on breast and endometrial tumor growth in athymic mice
-
O'Regan RM, Gajdos C, Dardes RC, et al. Effects of raloxifene after tamoxifen on breast and endometrial tumor growth in athymic mice. J Natl Cancer Inst 2002; 94:274-283. •• Study addressing the issue of how to manage women who have completed 5 years of adjuvant tamoxifen therapy but remain at increased risk of recurrence. In a mouse model of short-term tamoxifen exposed breast cancer, raloxifene was ineffective in blocking the stimulatory effects of low-dose estrogen and may therefore not be appropriate as sequential therapy after tamoxifen.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 274-283
-
-
O'Regan, R.M.1
Gajdos, C.2
Dardes, R.C.3
-
45
-
-
0000829131
-
Incident primary breast cancers are reduced by raloxifene: Integrated data from multi-center, double blind, randomised trials in 12 000 postmenopausal women
-
Jordan VC, Glusman SE, Glusman MEL, et al. Incident primary breast cancers are reduced by raloxifene: integrated data from multi-center, double blind, randomised trials in 12 000 postmenopausal women [abstract]. Breast Cancer Res Treat 1998; 50:227.
-
(1998)
Breast Cancer Res Treat
, vol.50
, pp. 227
-
-
Jordan, V.C.1
Glusman, S.E.2
Glusman, M.E.L.3
-
46
-
-
0035120523
-
Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-Year results from the MORE trial. Multiple outcomes of raloxifene evaluation
-
Cauley JA, Norton L, Lippman ME, et al. Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Multiple outcomes of raloxifene evaluation. Breast Cancer Res Treat 2001; 65:125-134.
-
(2001)
Breast Cancer Res Treat
, vol.65
, pp. 125-134
-
-
Cauley, J.A.1
Norton, L.2
Lippman, M.E.3
-
47
-
-
0035253379
-
Aromatase inhibitors in the treatment and prevention of breast cancer
-
Goss PE, Stausser K. Aromatase inhibitors in the treatment and prevention of breast cancer. J Clin Oncol 2001; 19:881-894.
-
(2001)
J Clin Oncol
, vol.19
, pp. 881-894
-
-
Goss, P.E.1
Stausser, K.2
-
48
-
-
0035922788
-
Aromatase inhibitors and inactivators in breast cancer
-
Lonning PE. Aromatase inhibitors and inactivators in breast cancer. BMJ 2001; 323:880-881.
-
(2001)
BMJ
, vol.323
, pp. 880-881
-
-
Lonning, P.E.1
-
49
-
-
0002149652
-
Antiaromatase agents: Preclinical data and neoadjuvant therapy
-
Miller WR, Dixon JM. Antiaromatase agents: preclinical data and neoadjuvant therapy. Clin Breast Cancer 2000; 1 (Suppl):S9-S14.
-
(2000)
Clin Breast Cancer
, vol.1
, Issue.SUPPL.
-
-
Miller, W.R.1
Dixon, J.M.2
-
50
-
-
0031663593
-
In vivo inhibition of aromatisation by exemestane, a novel irreversible aromatase inhibitor in postmenopausal breast cancer patients
-
Geisler J, King N, Anker G, et al. In vivo inhibition of aromatisation by exemestane, a novel irreversible aromatase inhibitor in postmenopausal breast cancer patients. Clin Cancer Res 1998; 4:2089-2093.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2089-2093
-
-
Geisler, J.1
King, N.2
Anker, G.3
-
51
-
-
0034669484
-
Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer therapy in postmenopausal women: Results of a North American multicenter randomised trial
-
Nabholtz A, Buzdar A, Pollak M, et al. Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer therapy in postmenopausal women: results of a North American multicenter randomised trial. J Clin Oncol 2000; 18:3758-3767.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3758-3767
-
-
Nabholtz, A.1
Buzdar, A.2
Pollak, M.3
-
52
-
-
0034669435
-
Anastrozole versus tamoxifen as first line therapy for advanced breast cancer in 668 postmenopausal women: Results of the tamoxifen or Arimidex Randomised Group Efficacy and Tolerability study
-
Bonneterre J, Thurlimann B, Robertson JFR, et al. Anastrozole versus tamoxifen as first line therapy for advanced breast cancer in 668 postmenopausal women: results of the tamoxifen or Arimidex Randomised Group Efficacy and Tolerability study. J Clin Oncol 2000; 18:3748-3757.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3748-3757
-
-
Bonneterre, J.1
Thurlimann, B.2
Robertson, J.F.R.3
-
53
-
-
0343584508
-
Superior efficacy of letrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer: Results of a phase III study of the International Letrozole Breast Cancer Group
-
Mouridsen H, Gershanovich M, Sun Y, et al. Superior efficacy of letrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer: results of a phase III study of the International Letrozole Breast Cancer Group. J Clin Oncol 2001; 19:2596-2606.
-
(2001)
J Clin Oncol
, vol.19
, pp. 2596-2606
-
-
Mouridsen, H.1
Gershanovich, M.2
Sun, Y.3
-
54
-
-
0037019752
-
The effects of tamoxifen and estrogen on brain metabolism in elderly women
-
Benson JR. The effects of tamoxifen and estrogen on brain metabolism in elderly women. J Natl Cancer Inst 2002; 94:1336-1337.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1336-1337
-
-
Benson, J.R.1
-
55
-
-
0026747130
-
Prognostic significance of progesterone receptor in estrogen receptor positive patients with metastatic breast cancer treated with tamoxifen: Results of a prospective Southwest Oncology Group Trial
-
Ravdin PM, Green S, Dorr TM, et al. Prognostic significance of progesterone receptor in estrogen receptor positive patients with metastatic breast cancer treated with tamoxifen: results of a prospective Southwest Oncology Group Trial. J Clin Oncol 1992; 10:1284-1291.
-
(1992)
J Clin Oncol
, vol.10
, pp. 1284-1291
-
-
Ravdin, P.M.1
Green, S.2
Dorr, T.M.3
-
56
-
-
0036235382
-
Tamoxifen resistant and refractory breast cancer
-
Goss PE, Strasser K. Tamoxifen resistant and refractory breast cancer. Drugs 2002; 62:957-966. • A comprehensive review of mechanisms of tamoxifen resistance and the potential value of aromatase inhibitors following acquisition of tamoxifen resistance.
-
(2002)
Drugs
, vol.62
, pp. 957-966
-
-
Goss, P.E.1
Strasser, K.2
-
57
-
-
8944237006
-
Anastrozole, a potent and selective aromatase inhibitor, versus megestrol acetate in postmenopausal women with advanced breast cancer: Results of overview analysis of two phase III trials
-
Buzdar A, Jonat W, Howell A, et al. Anastrozole, a potent and selective aromatase inhibitor, versus megestrol acetate in postmenopausal women with advanced breast cancer: results of overview analysis of two phase III trials. J Clin Oncol 1996; 14:2000-2011.
-
(1996)
J Clin Oncol
, vol.14
, pp. 2000-2011
-
-
Buzdar, A.1
Jonat, W.2
Howell, A.3
-
58
-
-
0035340766
-
Is anastrozole superior to tamoxifen as first-line therapy for advanced breast cancer?
-
Copur MS, Ledakis P, Bolton M, et al. Is anastrozole superior to tamoxifen as first-line therapy for advanced breast cancer? [letter]. J Clin Oncol 2001; 19:2578.
-
(2001)
J Clin Oncol
, vol.19
, pp. 2578
-
-
Copur, M.S.1
Ledakis, P.2
Bolton, M.3
-
59
-
-
0035340766
-
Is anastrozole superior to tamoxifen as first-line therapy for advanced breast cancer?
-
Bagley CM, Rowbotham RK, et al. Is anastrozole superior to tamoxifen as first-line therapy for advanced breast cancer? [letter]. J Clin Oncol 2001; 19:2579.
-
(2001)
J Clin Oncol
, vol.19
, pp. 2579
-
-
Bagley, C.M.1
Rowbotham, R.K.2
-
60
-
-
0035340766
-
Is anastrozole superior to tamoxifen as first-line therapy for advanced breast cancer?
-
Costa SD. Is anastrozole superior to tamoxifen as first-line therapy for advanced breast cancer? [letter]. J Clin Oncol 2001; 19:2580.
-
(2001)
J Clin Oncol
, vol.19
, pp. 2580
-
-
Costa, S.D.1
-
61
-
-
0035884620
-
Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1 and/or ErbB-2-positive, estrogen receptor positive primary breast cancer: Evidence from a phase III randomised trial
-
Ellis MJ, Coop A, Singh B, et al. Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1 and/or ErbB-2-positive, estrogen receptor positive primary breast cancer: evidence from a phase III randomised trial. J Clin Oncol 2001; 19:3808-3816.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3808-3816
-
-
Ellis, M.J.1
Coop, A.2
Singh, B.3
-
62
-
-
0037083289
-
Comparison of the systemic and intratumoral effects of tamoxifen and the aromatase inhibitor vorozole in postmenopausal patients with primary breast cancer
-
Harper-Wynne CL, Sacks NPM, Shenton K, et al. Comparison of the systemic and intratumoral effects of tamoxifen and the aromatase inhibitor vorozole in postmenopausal patients with primary breast cancer. J Clin Oncol 2002; 20:1026-1035.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1026-1035
-
-
Harper-Wynne, C.L.1
Sacks, N.P.M.2
Shenton, K.3
-
63
-
-
0035884408
-
Comparison of the short-term biological effects of 7 alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)-nonyl] estra-1,3,5,(10)-triene-3,17β-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer
-
Robertson JF, Nicholson RI, Bundred NJ, et al. Comparison of the short-term biological effects of 7 alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)-nonyl]. estra-1,3,5,(10)-triene-3,17β-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer. Cancer Res 2001; 61:6739-6746.
-
(2001)
Cancer Res
, vol.61
, pp. 6739-6746
-
-
Robertson, J.F.1
Nicholson, R.I.2
Bundred, N.J.3
-
64
-
-
0032135328
-
Tamoxifen in early breast cancer
-
Benson JR. Tamoxifen in early breast cancer. Lancet 1998; 352:404-405.
-
(1998)
Lancet
, vol.352
, pp. 404-405
-
-
Benson, J.R.1
-
65
-
-
0035806484
-
National Institutes of Health Consensus Development Corfference Statement: Adjuvant therapy for breast cancer, November 1-3, 2000
-
National Institutes of Health Consensus Development Corfference Statement: adjuvant therapy for breast cancer, November 1-3, 2000. J Natl Cancer Inst 2001; 93:979-984. •• Concise and pragmatic summary of current treatment recommendations for systemic adjuvant therapies (endocrine and chemotherapy) and postmastectomy radiotherapy by a 14-member panel of leading experts from the fields of oncology, radiology, surgery, pathology, public health and health policy.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 979-984
-
-
-
66
-
-
0035884636
-
Meeting highlights: International Consensus Panel on the treatment of primary breast cancer
-
Goldhirsch A, Glick JH, Gelber RD, et al. Meeting highlights: International Consensus Panel on the treatment of primary breast cancer. J Clin Oncol 2001; 19:3817-3827.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3817-3827
-
-
Goldhirsch, A.1
Glick, J.H.2
Gelber, R.D.3
-
67
-
-
0036211226
-
Tamoxifen plus chemotherapy versus tamoxifen alone as adjuvant therapies for node-positive postmenopausal women with early breast cancer: A Stochastic Economic Evaluation
-
Karnon J, Brown J. Tamoxifen plus chemotherapy versus tamoxifen alone as adjuvant therapies for node-positive postmenopausal women with early breast cancer: a Stochastic Economic Evaluation. Pharmacoeconomics 2002; 20:119-137.
-
(2002)
Pharmacoeconomics
, vol.20
, pp. 119-137
-
-
Karnon, J.1
Brown, J.2
-
68
-
-
0035863386
-
Adjuvant tamoxifen: Predictors of use, side effects and discontinuation in older women
-
Demissie S, Silliman RA, Lash TL. Adjuvant tamoxifen: predictors of use, side effects and discontinuation in older women. J Clin Oncol 2001; 19:322-328.
-
(2001)
J Clin Oncol
, vol.19
, pp. 322-328
-
-
Demissie, S.1
Silliman, R.A.2
Lash, T.L.3
-
69
-
-
0003301036
-
Non-adherence with adjuvant tamoxifen therapy in women with early stage breast cancer
-
Partridge AH, Wang PS, Winer EP, et al. Non-adherence with adjuvant tamoxifen therapy in women with early stage breast cancer [abstract]. Proc Am Soc Clin Oncol 2001; 20:238a.
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
-
-
Partridge, A.H.1
Wang, P.S.2
Winer, E.P.3
-
70
-
-
0036605561
-
Adjuvant tamoxifen prescription in women 65 years and older with primary breast cancer
-
Silliman R, Guadagnoli E, Rakowski W, et al. Adjuvant tamoxifen prescription in women 65 years and older with primary breast cancer. J Clin Oncol 2002; 20:2680-2688.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2680-2688
-
-
Silliman, R.1
Guadagnoli, E.2
Rakowski, W.3
-
71
-
-
0035795683
-
Five versus more than tive years of tamoxifen for lymph node-negative breast cancer: Updated findings of the National Surgical Adjuvant Breast and Bowel Project B-14 randomised trial
-
Fisher B, Dignam J, Bryant J, et al. Five versus more than tive years of tamoxifen for lymph node-negative breast cancer: updated findings of the National Surgical Adjuvant Breast and Bowel Project B-14 randomised trial. J Natl Cancer Inst 2001; 93:684-690. •• Large study confirming that more prolonged adjuvant tamoxifen therapy beyond 5 years confers no survival benefit and no statistically significant reduction in contralateral tumours following the second randomization. Further discussed in correspondence [72].
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 684-690
-
-
Fisher, B.1
Dignam, J.2
Bryant, J.3
-
72
-
-
0035802181
-
Five versus more than tive years of tamoxifen for lymph node-negative breast cancer: Updated findings of the National Surgical Adjuvant Breast and Bowel Project B-14 randomised trial
-
Benson JR. Five versus more than tive years of tamoxifen for lymph node-negative breast cancer: updated findings of the National Surgical Adjuvant Breast and Bowel Project B-14 randomised trial. J Natl Cancer Inst 2001; 93:1493-1494.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1493-1494
-
-
Benson, J.R.1
-
73
-
-
0035884430
-
Tamoxifen for patients with estrogen receptor-negative breast cancer
-
Swain S. Tamoxifen for patients with estrogen receptor-negative breast cancer. J Clin Oncol 2001; 19:93-97. •• Critical review of the evidence for benefits of tamoxifen in patients with truly estrogen receptor-negative tumours, examining primary breast cancer survival, contralateral breast cancer and beneficial estrogen agonist activities. Overall conclusion on tamoxifen not indicated for this subgroup, but a warning is given on misclassification of estrogen receptor status based on false negative immunohistochemistry results and failure of some assays to detect estrogen receptor beta.
-
(2001)
J Clin Oncol
, vol.19
, pp. 93-97
-
-
Swain, S.1
-
74
-
-
0035865147
-
Tamoxifen and chemotherapy for axillary node-negative, estrogen receptor-negative breast cancer: Findings from National Surgical Adjuvant Breast and Bowel Project B-23
-
Fisher B, Anderson S, Tan-Chiu E, et al. Tamoxifen and chemotherapy for axillary node-negative, estrogen receptor-negative breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-23. J Clin Oncol 2001; 19:931-942.
-
(2001)
J Clin Oncol
, vol.19
, pp. 931-942
-
-
Fisher, B.1
Anderson, S.2
Tan-Chiu, E.3
-
75
-
-
0002642314
-
CMF versus CAF ± tamoxifen in highrisk node-negative breast cancer patients and a natural history follow-up study in low-risk node-negative patients: Update of tamoxifen results
-
Hutchins L, Green S, Ravdin P, et al. CMF versus CAF ± tamoxifen in highrisk node-negative breast cancer patients and a natural history follow-up study in low-risk node-negative patients: Update of tamoxifen results [abstract]. Breast Cancer Res Treat 1999; 57:25.
-
(1999)
Breast Cancer Res Treat
, vol.57
, pp. 25
-
-
Hutchins, L.1
Green, S.2
Ravdin, P.3
-
77
-
-
0035806486
-
Tamoxifen therapy for primary breast cancer and risk of contralateral breast cancer
-
Li CI, Malone KE, Weiss NS, Daling JR. Tamoxifen therapy for primary breast cancer and risk of contralateral breast cancer. J Natl Cancer Inst 2001; 93:1008-1013. • Controversial retrospective cohort study (8981 patients) which failed to show a statistically significant reduction in incidence of contralateral breast cancer in patients treated with adjuvant tamoxifen with no chemotherapy. Also reported an increase in estrogen receptor-negative contralateral breast cancers but no survival differences. Inconsistent with other studies and questions raised about classification of estrogen receptor status.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1008-1013
-
-
Li, C.I.1
Malone, K.E.2
Weiss, N.S.3
Daling, J.R.4
-
79
-
-
0034597916
-
Tamoxifen and risk of contralateral breast cancer in BRCA-1 and BRCA-2 mutation carriers: A case-control study
-
Hereditary Breast Cancer Clinical Study Group
-
Narod SA, Brunet JS, Ghadirian P, et al. Tamoxifen and risk of contralateral breast cancer in BRCA-1 and BRCA-2 mutation carriers: a case-control study. Hereditary Breast Cancer Clinical Study Group. Lancet 2000; 356:1876-1881.
-
(2000)
Lancet
, vol.356
, pp. 1876-1881
-
-
Narod, S.A.1
Brunet, J.S.2
Ghadirian, P.3
-
80
-
-
0035861037
-
Tamoxifen and breast cancer incidence among women with inherited mutations in BRCA-1 and BRCA-2
-
King M-C, Wieand S, Hale K, et al. Tamoxifen and breast cancer incidence among women with inherited mutations in BRCA-1 and BRCA-2. JAMA 2001; 286:2251-2256. • Important analysis of differential effects of tamoxifen as chemopreventive agents amongst women with BRCA-1 and BRCA-2 inherited mutations in the NSABP P-1 trial.
-
(2001)
JAMA
, vol.286
, pp. 2251-2256
-
-
King, M.-C.1
Wieand, S.2
Hale, K.3
-
81
-
-
0036001333
-
Tamoxifen, hormone receptors and hormone replacement therapy in women previously treated for breast cancer: A cohort study
-
Dew JE, Wren BG, Eden JA. Tamoxifen, hormone receptors and hormone replacement therapy in women previously treated for breast cancer: a cohort study. Climacteric 2002; 5:151-155. • A short study examining the effects of HRT in combination with tamoxifen therapy in breast cancer patients with menopausal symptoms (342 patients available for analysis). Hazard ratios for all types of hormone therapy (combined estrogenprogestogen, progestogen only or topical estrogen) and concurrent tamoxifen showed a nonsignificant decrease in risk of breast cancer recurrence associated with tamoxifen use, including a subset analysis of estrogen receptor-positive tumours. Larger prospective randomized trials are required to further address this issue of HRT use in breast cancer survivors.
-
(2002)
Climacteric
, vol.5
, pp. 151-155
-
-
Dew, J.E.1
Wren, B.G.2
Eden, J.A.3
-
82
-
-
0030581589
-
Risk of venous thromboembolism in use of hormone replacement therapy
-
Daly E, Vessey MP, Hawkins MM, et al. Risk of venous thromboembolism in use of hormone replacement therapy. Lancet 1996; 348:977-980.
-
(1996)
Lancet
, vol.348
, pp. 977-980
-
-
Daly, E.1
Vessey, M.P.2
Hawkins, M.M.3
-
83
-
-
0347450835
-
Tamoxifen and contralateral breast cancer
-
Cuzik J, Baum M. Tamoxifen and contralateral breast cancer [letter]. Lancet 1985; 2:282.
-
(1985)
Lancet
, vol.2
, pp. 282
-
-
Cuzik, J.1
Baum, M.2
-
84
-
-
0032508293
-
Prevention of breast cancer with tamoxifen: Preliminary findings from the Italian randomised trial among hysterectomised women
-
Veronesi U, Maisonneuve P, Costa A, et al. Prevention of breast cancer with tamoxifen: preliminary findings from the Italian randomised trial among hysterectomised women. Lancet 1998; 362:93-97.
-
(1998)
Lancet
, vol.362
, pp. 93-97
-
-
Veronesi, U.1
Maisonneuve, P.2
Costa, A.3
-
85
-
-
0032508294
-
Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial
-
Powles T, Eeles R, Ashley S, et al. Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial. Lancet 1998; 362:98-101.
-
(1998)
Lancet
, vol.362
, pp. 98-101
-
-
Powles, T.1
Eeles, R.2
Ashley, S.3
-
86
-
-
0037197090
-
Tamoxifen for breast cancer among hysterectomised women
-
Veronesi U, Maisonneuve P, Sacchini V, et al. Tamoxifen for breast cancer among hysterectomised women. Lancet 2002; 359:122-124. • Follow-up study reinforcing earlier conclusions that tamoxifen does not significantly reduce rate of breast cancer in hysterectomized women. Suggestion that tamoxifen may partly negate increased risk of breast cancer associated with HRT use. This is further discussed in correspondence [87].
-
(2002)
Lancet
, vol.359
, pp. 122-124
-
-
Veronesi, U.1
Maisonneuve, P.2
Sacchini, V.3
-
87
-
-
0344019690
-
Tamoxifen for breast cancer in hysterectomised women
-
in press
-
Benson JR. Tamoxifen for breast cancer in hysterectomised women [letter]. Lancet (in press).
-
Lancet
-
-
Benson, J.R.1
-
88
-
-
0032848782
-
Health-related quality of life and tamoxifen in breast cancer prevention: A report from the National Surgical Adjuvant Breast and Bowel Project P-1
-
Day R, Ganz P, Costantino JP, et al. Health-related quality of life and tamoxifen in breast cancer prevention: a report from the National Surgical Adjuvant Breast and Bowel Project P-1. J Clin Oncol 1999; 17:2659-2669.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2659-2669
-
-
Day, R.1
Ganz, P.2
Costantino, J.P.3
-
90
-
-
0033199926
-
Breast cancer risk after bilateral prophylactic oophorectomy in BR CA-1 mutation carriers
-
Rebbeck TR, Levin AM, Eisen A, et al. Breast cancer risk after bilateral prophylactic oophorectomy in BR CA-1 mutation carriers. J Natl Cancer Inst 1999; 91:1475-1479.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1475-1479
-
-
Rebbeck, T.R.1
Levin, A.M.2
Eisen, A.3
-
91
-
-
0035884449
-
Reducing the risk of breast cancer with tamoxifen in women at increased risk
-
Vogel VG. Reducing the risk of breast cancer with tamoxifen in women at increased risk. J Clin Oncol 2001; 1987-92. • Development of a quantitative model to estimate breast cancer risk and hence apply risk reduction strategies which are in accordance with Food and Drug Administration directives on the use of tamoxifen to reduce incidence of breast cancer amongst women at increased risk.
-
(2001)
J Clin Oncol
, pp. 1987-1992
-
-
Vogel, V.G.1
-
92
-
-
0032528215
-
Steroid receptors in hereditary breast carcinomas associated with BRCA-1 or BRCA-2 mutations or unknown susceptibility genes
-
Loman N, Johannsson O, Bendahl PO, et al. Steroid receptors in hereditary breast carcinomas associated with BRCA-1 or BRCA-2 mutations or unknown susceptibility genes. Cancer 1998; 83:310-319.
-
(1998)
Cancer
, vol.83
, pp. 310-319
-
-
Loman, N.1
Johannsson, O.2
Bendahl, P.O.3
-
93
-
-
0033199926
-
Reduction in breast cancer risk after bilateral prophylactic oophorectomy in BRCA-1 mutation carriers
-
Rebbeck TR, Levin AM, Eisen A, et al. Reduction in breast cancer risk after bilateral prophylactic oophorectomy in BRCA-1 mutation carriers. J Natl Cancer Inst 1999; 91:1475-1479.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1475-1479
-
-
Rebbeck, T.R.1
Levin, A.M.2
Eisen, A.3
-
94
-
-
0024801278
-
Projecting individualised probabilities of developing breast cancer for white females who are being examined annually
-
Gail MH, Brinton LA, Byar DP, et al. Projecting individualised probabilities of developing breast cancer for white females who are being examined annually. J Natl Cancer Inst 1989; 81:1879-1886.
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 1879-1886
-
-
Gail, M.H.1
Brinton, L.A.2
Byar, D.P.3
-
96
-
-
0036138716
-
Outcomes of tamoxifen chemoprevention for breast cancer in very high risk women: A cost-effectiveness analysis
-
Hershman D, Sundararajan V, Jacobson JS, et al. Outcomes of tamoxifen chemoprevention for breast cancer in very high risk women: a cost-effectiveness analysis. J Clin Oncol 2002; 20:9-16.
-
(2002)
J Clin Oncol
, vol.20
, pp. 9-16
-
-
Hershman, D.1
Sundararajan, V.2
Jacobson, J.S.3
-
97
-
-
0032417681
-
Immunohistologic analysis of estrogen receptor expression in breast carcinoma precursor lesions
-
Visscher DW, Padiyar N, Long D, et al. Immunohistologic analysis of estrogen receptor expression in breast carcinoma precursor lesions. Breast J 1998; 4:447-451.
-
(1998)
Breast J
, vol.4
, pp. 447-451
-
-
Visscher, D.W.1
Padiyar, N.2
Long, D.3
-
98
-
-
0028318783
-
Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells
-
Ottaviano YL, Issa JP, Parl FF, et al. Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res 1994; 54:2552-2555.
-
(1994)
Cancer Res
, vol.54
, pp. 2552-2555
-
-
Ottaviano, Y.L.1
Issa, J.P.2
Parl, F.F.3
-
99
-
-
0032925166
-
Pattern of distribution of cells positive for estrogen receptor alpha and progesterone receptor in relation to proliferating cells in the mammary gland
-
Russo J, Ao X, Grill C, et al. Pattern of distribution of cells positive for estrogen receptor alpha and progesterone receptor in relation to proliferating cells in the mammary gland. Breast Cancer Res Treat 1999; 53:217-227.
-
(1999)
Breast Cancer Res Treat
, vol.53
, pp. 217-227
-
-
Russo, J.1
Ao, X.2
Grill, C.3
-
100
-
-
0035687514
-
Beyond tamoxifen: New endpoints for breast cancer chemoprevention, new drugs for breast cancer prevention
-
Fabian CJ, Kimler BF. Beyond tamoxifen: new endpoints for breast cancer chemoprevention, new drugs for breast cancer prevention. Ann N Y Acad Sci 2001; 952:44-45. •• An excellent and insightful account of new drug development for breast cancer prevention and methods for evaluating clinical efficacy using modulation of molecular markers and breast intraepithelial neoplasia as endpoints for response.
-
(2001)
Ann N Y Acad Sci
, vol.952
, pp. 44-45
-
-
Fabian, C.J.1
Kimler, B.F.2
-
101
-
-
0035057776
-
Breast cancer chemoprevention: Beyond tamoxifen
-
Fabian CJ. Breast cancer chemoprevention: beyond tamoxifen. Breast Cancer Res Treat 2001; 3:99-103.
-
(2001)
Breast Cancer Res Treat
, vol.3
, pp. 99-103
-
-
Fabian, C.J.1
-
102
-
-
0344019688
-
Changing philosophical perspectives in breast cancer
-
Tobias J, Houghton J, Henderson C, editors. London, Arnold Publishers
-
Benson JR, Baum M. Changing philosophical perspectives in breast cancer. In: Tobias J, Houghton J, Henderson C, editors. Breast cancer: new horizons in research and treatment. London, Arnold Publishers; 2001. pp. 12-29.
-
(2001)
Breast Cancer: New Horizons in Research and Treatment
, pp. 12-29
-
-
Benson, J.R.1
Baum, M.2
|