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Volumn 18, Issue 1, 2003, Pages 18-22

Small G proteins as novel therapeutic targets in cardiovascular medicine

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; GTP BINDING PROTEINS; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; RECOMBINANT INTERLEUKIN 1BETA;

EID: 0037292463     PISSN: 08861714     EISSN: None     Source Type: Journal    
DOI: 10.1152/nips.01407.2002     Document Type: Article
Times cited : (20)

References (17)
  • 1
    • 0034717136 scopus 로고    scopus 로고
    • Small guanine nucleotide-binding proteins and myocardial hypertrophy
    • Clerk A and Sugden PH. Small guanine nucleotide-binding proteins and myocardial hypertrophy. Circ Res 86: 1019-1023, 2000.
    • (2000) Circ Res , vol.86 , pp. 1019-1023
    • Clerk, A.1    Sugden, P.H.2
  • 2
    • 0035964808 scopus 로고    scopus 로고
    • Thrombin suppresses endothelial nitric oxide synthase and upregulates endothelin-converting enzyme-1 expression by distinct pathways: Role of Rho/ROCK and mitogen-activated protein kinase
    • Eto M, Barandier C, Rathgeb L, Kozai T, Joch H, Yang Z, and Luscher TF. Thrombin suppresses endothelial nitric oxide synthase and upregulates endothelin-converting enzyme-1 expression by distinct pathways: role of Rho/ROCK and mitogen-activated protein kinase. Circ Res 89: 583-590, 2001.
    • (2001) Circ Res , vol.89 , pp. 583-590
    • Eto, M.1    Barandier, C.2    Rathgeb, L.3    Kozai, T.4    Joch, H.5    Yang, Z.6    Luscher, T.F.7
  • 3
    • 0036051323 scopus 로고    scopus 로고
    • Effects of HMG-CoA reductase inhibitors on skeletal muscle: Are all statins the same?
    • Evans M and Rees A. Effects of HMG-CoA reductase inhibitors on skeletal muscle: are all statins the same? Drug Saf 25: 649-663, 2002.
    • (2002) Drug Saf , vol.25 , pp. 649-663
    • Evans, M.1    Rees, A.2
  • 4
    • 0037150157 scopus 로고    scopus 로고
    • Functional inhibition of Ras by S-trans,trans-farnesyl thiosalicylic acid attenuates atherosclerosis in apolipoprotein E knockout mice
    • George J, Afek A, Keren P, Herz I, Goldberg I, Haklai R, Kloog Y, and Keren G. Functional inhibition of Ras by S-trans,trans-farnesyl thiosalicylic acid attenuates atherosclerosis in apolipoprotein E knockout mice. Circulation 105: 2416-2422, 2002.
    • (2002) Circulation , vol.105 , pp. 2416-2422
    • George, J.1    Afek, A.2    Keren, P.3    Herz, I.4    Goldberg, I.5    Haklai, R.6    Kloog, Y.7    Keren, G.8
  • 5
    • 0037160587 scopus 로고    scopus 로고
    • Statins and myopathy
    • Hargreaves IP and Heales S. Statins and myopathy. Lancet 359: 711-712, 2002.
    • (2002) Lancet , vol.359 , pp. 711-712
    • Hargreaves, I.P.1    Heales, S.2
  • 6
    • 0346736491 scopus 로고    scopus 로고
    • Effects of the 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin- 1 and endothelial nitric oxide synthase in vascular endothelial cells
    • Hernandez-Perera O, Perez-Sala D, Navarro-Antolin J, Sanchez-Pascuala R, Hernandez G, Diaz C, and Lamas S. Effects of the 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells. J Clin Invest 101: 2711-2719, 1998.
    • (1998) J Clin Invest , vol.101 , pp. 2711-2719
    • Hernandez-Perera, O.1    Perez-Sala, D.2    Navarro-Antolin, J.3    Sanchez-Pascuala, R.4    Hernandez, G.5    Diaz, C.6    Lamas, S.7
  • 7
    • 0033525188 scopus 로고    scopus 로고
    • Kip degradation through its regulation of cyclin E/CDK 2 activity
    • Kip degradation through its regulation of cyclin E/CDK2 activity. J Biol Chem 274: 3396-3401, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 3396-3401
    • Hu, W.1    Bellone, C.J.2    Baldassare, J.J.3
  • 8
    • 0037007047 scopus 로고    scopus 로고
    • Enhanced contractile mechanisms in vasospasm: Is endothelial dysfunction the whole story?
    • Lamping KG. Enhanced contractile mechanisms in vasospasm: is endothelial dysfunction the whole story? Circulation 105: 1520-1522, 2002.
    • (2002) Circulation , vol.105 , pp. 1520-1522
    • Lamping, K.G.1
  • 9
    • 0034253196 scopus 로고    scopus 로고
    • Small G-protein networks: Their crosstalk and signal cascades
    • Matozaki T, Nakanishi H, and Takai Y. Small G-protein networks: their crosstalk and signal cascades. Cell Signal 12: 515-524, 2000.
    • (2000) Cell Signal , vol.12 , pp. 515-524
    • Matozaki, T.1    Nakanishi, H.2    Takai, Y.3
  • 10
    • 0035680464 scopus 로고    scopus 로고
    • In vivo gene transfer of dominant-negative rho-kinase induces regression of coronary arteriosclerosis in pigs
    • Morishige K, Shimokawa H, Eto Y, Hoshijima M, Kaibuchi K, and Takeshita A. In vivo gene transfer of dominant-negative rho-kinase induces regression of coronary arteriosclerosis in pigs. Ann NY Acad Sci 947: 407-411, 2001.
    • (2001) Ann NY Acad Sci , vol.947 , pp. 407-411
    • Morishige, K.1    Shimokawa, H.2    Eto, Y.3    Hoshijima, M.4    Kaibuchi, K.5    Takeshita, A.6
  • 11
    • 0035860840 scopus 로고    scopus 로고
    • Increased expression and activity of RhoA are associated with increased DNA synthesis and reduced p27(Kip1) expression in the vasculature of hypertensive rats
    • Seasholtz TM, Zhang T, Morissette MR, Howes AL, Yang AH, and Brown JH. Increased expression and activity of RhoA are associated with increased DNA synthesis and reduced p27(Kip1) expression in the vasculature of hypertensive rats. Circ Res 89: 488-495, 2001.
    • (2001) Circ Res , vol.89 , pp. 488-495
    • Seasholtz, T.M.1    Zhang, T.2    Morissette, M.R.3    Howes, A.L.4    Yang, A.H.5    Brown, J.H.6
  • 12
    • 0034650714 scopus 로고    scopus 로고
    • Signal transduction by G-proteins, Rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II
    • Somlyo AP and Somlyo AV. Signal transduction by G-proteins, Rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol 522: 177-185, 2000.
    • (2000) J Physiol , vol.522 , pp. 177-185
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 13
    • 0037075262 scopus 로고    scopus 로고
    • Cerivastatin and reports of fatal rhabdomyolysis
    • Staffa JA, Chang J, Green L. Cerivastatin and reports of fatal rhabdomyolysis. N Engl J Med 346: 539-540, 2002.
    • (2002) N Engl J Med , vol.346 , pp. 539-540
    • Staffa, J.A.1    Chang, J.2    Green, L.3
  • 14
    • 0035572718 scopus 로고    scopus 로고
    • Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
    • Takemoto M and Liao JK. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 21: 1712-1719, 2001.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1712-1719
    • Takemoto, M.1    Liao, J.K.2
  • 16
    • 0035949639 scopus 로고    scopus 로고
    • Short-term local delivery of an inhibitor of Ras farnesyltransferase prevents neointima formation in vivo after porcine coronary balloon angioplasty
    • Work LM, McPhaden AR, Pyne NJ, Pyne S, Wadsworth RM, and Wainwright CL. Short-term local delivery of an inhibitor of Ras farnesyltransferase prevents neointima formation in vivo after porcine coronary balloon angioplasty. Circulation 104: 1538-1543, 2001.
    • (2001) Circulation , vol.104 , pp. 1538-1543
    • Work, L.M.1    McPhaden, A.R.2    Pyne, N.J.3    Pyne, S.4    Wadsworth, R.M.5    Wainwright, C.L.6
  • 17
    • 0034332685 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibition improves endothelial cell function and inhibits smooth muscle cell proliferation in human saphenous veins
    • Yang Z, Kozai T, van der Loo B, Viswambharan H, Lachat M, Turina MI, Malinski T, and Luscher TF. HMG-CoA reductase inhibition improves endothelial cell function and inhibits smooth muscle cell proliferation in human saphenous veins. J Am Coll Cardiol 36: 1691-1697, 2000.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1691-1697
    • Yang, Z.1    Kozai, T.2    Van Der Loo, B.3    Viswambharan, H.4    Lachat, M.5    Turina, M.I.6    Malinski, T.7    Luscher, T.F.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.