Biological activity and synthetic metodologies for the preparation fluoroquinoles, a class of potent antibacterial agents

Current Medicinal Chemistry

Volumn 10, Issue 1, 2003, Pages 21-39

  Da Silva, Adilson D ^a   De Almeida, Mauro V ^a   De Souza, Marcus V N ^a   Couri, Mara R C ^a  

^a FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

1 ETHYL 7 [3 (ETHYLAMINOMETHYL) 1 PYRROLIDINYL] 6,8 DIFLUORO 1,4 DIHYDRO 4 OXO 3 QUINOLINECARBOXYLIC ACID; 1 TERT BUTYL 7 (2,5 DIAZABICYCLO[2.2.1]HEPTAN 2 YL) 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 7 (3 AMINO 1 PYRROLIDINYL) 1 CYCLOPROPYL 6,8 DIFLUORO 1,4 DIHYDRO 4 OXO 3 QUINOLINECARBOXYLIC ACID; 9 CYCLOPROPYL 6 FLUORO 3,4 DIOXO 7 (1 PIPERAZINYL)ISOTHIAZOLO[5,4 B]QUINOLINE; 9 FLUORO 6,7 DIHYDRO 5 METHYL 8 (4 METHYL 1 PIPERAZINYL) 1 OXO 1H,5H BENZO[IJ]QUINOLIZINE 2 CARBOXYLIC ACID; 9 FLUORO 6,7 DIHYDRO 5 METHYL 8 (4 METHYL 1 PIPERAZINYL) 1,7 DIOXO 1H,5H BENZO[IJ]QUINOLIZINE 2 CARBOXYLIC ACID; AMIFLOXACIN; CINOXACIN; CIPROFLOXACIN; CLINAFLOXACIN; DANOFLOXACIN; DIFLOXACIN; ENROFLOXACIN; FLEROXACIN; FLUMEQUINE; IBAFLOXACIN; LEVOFLOXACIN; LOMEFLOXACIN; MILOXACIN; NALIDIXIC ACID; NORDIFLOXACIN; NORFLOXACIN; OFLOXACIN; PEFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RUFLOXACIN; SPARFLOXACIN; TEMAFLOXACIN; TOSUFLOXACIN; UNINDEXED DRUG;

ANAEROBIC BACTERIUM; ANTHRAX; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; BACTERIAL INFECTION; BIOLOGICAL WARFARE; CHEMICAL MODIFICATION; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; METHODOLOGY; MYCOBACTERIUM; NONHUMAN; REVIEW; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFECTIVE AGENTS; BACTERIA; DRUG RESISTANCE, BACTERIAL; FLUOROQUINOLONES; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037241209     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033368637     Document Type: Review

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