Synthesis of 7-benzoxazol-2-yl and 7-Benzothiazol-2-yl-6-fluoro- quinolones

Journal of Heterocyclic Chemistry

Volumn 35, Issue 6, 1998, Pages 1301-1304

  Richardson, Thomas O ^a   Shanbhag, Vinayak P ^a   Adair, Kimberly ^a   Smith, Shantel ^a  

^a BETHUNE COOKMAN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 BENZOTHIAZOL 2 YL 6 FLUOROQUINOLONE; 7 BENZOXAZOL 2 YL 6 FLUOROQUINOLONE; IRLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CYCLIZATION; DRUG SYNTHESIS; FOURIER TRANSFORMATION; HYDROLYSIS; INFRARED RADIATION; REACTION ANALYSIS; SOLUBILITY; STRUCTURE ANALYSIS;

EID: 0032419915     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570350610     Document Type: Article

References (17)

1. H. Koga, A. Itoh, S. Murayama, S. Susue and T. Irikura, J. Med. Chem., 23, 1358 (1980).
2. [2a] J. Esteve Soler, French patent 2,548,664 (1985); Chem. Abst., 103, 87184a (1985);
3. [b] T. Uno, M. Takamatsu, Y. Inoue, Y. Kawahata, K. Inchi and G. Tsukamoto, J. Med. Chem., 30, 2163 (1987).
4. Y. Goueffon, G. Montay, F. Roquet and M. Pesson, C. R. Acad. Sci., Ser. 3, 292, 37 (1981).
5. D. T. W. Chu and P. B. Fernandes, Antimicrob. Agents Chemother., 33, 131 (1989).
6. J. M. Domagala, L. D. Hanna, C. L. Heifetz, M. P. Huff, T. F. Mich, J. P. Sanchez and M. Solomon, J. Med. Chem., 29, 394 (1986).
7. D. T. W. Chu and P. B. Fernandes, Advan. Drug Res., 21, 39 (1991).
8. T. Rosen, Progr. Med. Chem., 27, 235 (1990).
9. L. A. Mitscher, P. Devasthale and R. Zavod, Quinolone Antimicrobial Agents, 2nd Ed, D. C. Hooper and J. S. Wolfson, eds, American Society for Biology, Washington, D. C., 1993, pp 3-51.
10. Y. Asahina, T. Ishizaki and S. Suzzue, Progr. Drug Res., 38, 57 (1992).
11. M. Reuman, S. J. Daum, B. Singh, M. P. Wentland, R. B. Perni, P. Pennock, P. M. Carbateas, M. D. Gruett, M. T. Saindane, P. H. Dorff, S. A. Coughlin, D. M. Sedlock, J. B. Rake and G. Y. Lesher, J. Med. Chem., 38, 2531 (1995).
12. M. F. Brana, J. M. Castellano and M. J. R. Yunta, J. Heterocyclic Chem., 27, 1177 (1990).
13. R. J. Gould and W. A. Jacobs, J. Am. Chem. Soc., 61, 2890 (1939).
14. I. A. Entwhistle, R. A. W. Johnstone, and T. J. Povall, J. Chem. Soc., Perkin Trans I, 1300 (1975).
15. D. W. Hein, R. J. Alheim, and J. J. Leavitt, J. Am. Chem. Soc., 79, 427 (1957).
16. M. Bil, Chem. Ind. (London), 27, 892 (1970).
17. S. E. Drewes, H. E. M. Magolo and D. Sutton, J. Chem. Soc., Perkin Trans. I, 1283 (1975).