Synthesis and antimicrobial activity of 4H-4-oxoquinolizine derivatives: Consequences of structural modification at the C-8 position

Journal of Medicinal Chemistry

Volumn 42, Issue 20, 1999, Pages 4202-4213

  Ma, Zhenkun ^a   Chu, Daniel T W ^a   Cooper, Curt S ^a   Li, Qun ^a   Fung, Anthony K L ^a   Wang, Sanyi ^a   Shen, Linus L ^a   Flamm, Robert K ^a   Nilius, Angela M ^a   Alder, Jeffery D ^a   Meulbroek, Jonathan A ^a   Or, Yat Sun ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4H 4 OXOQUINOLINE DERIVATIVE; 8 (3 AMINO 1 PYRROLIDINYL) 1 CYCLOPROPYL 7 FLUORO 9 METHYL 4 OXO 3 QUINOLIZINECARBOXYLIC ACID; CIPROFLOXACIN; METICILLIN; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG TOLERABILITY; STEREOCHEMISTRY; SYNTHESIS;

ANIMALS; ANTI-BACTERIAL AGENTS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MICE; QUINOLIZINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033533871     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990191k     Document Type: Article

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