Modulation of endotoxin-induced endothelial activity by microtubule depolymerization

Journal of Trauma

Volumn 54, Issue 1, 2003, Pages 104-113

  Cuschieri, Joseph ^a   Gourlay, David ^b   Garcia, Iris ^b   Jelacic, Sandra ^b   Maier, Ronald V ^b  

^a UNIVERSITY OF CINCINNATI   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Adhesion; Endothelial; Endotoxin; ERK 1 2; Intercellular adhesion molecule 1; Interleukin 8; Neutrophil; Nuclear factor B

Indexed keywords

ADAPTOR PROTEIN; COLCHICINE; ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

CELL ADHESION; CELL MIGRATION; CELL STIMULATION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOFLUOROMETRY; DEPOLYMERIZATION; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; MICROTUBULE; PHENOTYPE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADAPTOR PROTEIN COMPLEX 1; BLOTTING, WESTERN; CELLS, CULTURED; COLCHICINE; CYCLOOXYGENASE 2; DINOPROSTONE; DROSOPHILA PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-8; ISOENZYMES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICROTUBULES; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NEUTROPHIL ACTIVATION; NEUTROPHIL INFILTRATION; NF-KAPPA B; POLYMERS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECEPTORS, CELL SURFACE; SEPSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; UMBILICAL VEINS;

EID: 0037237407     PISSN: 00225282     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005373-200301000-00013     Document Type: Article

References (55)

1. Waage A, Brandtzaeg P, Espevik T, Halstensen A. Current understanding of the pathogenesis of gram-negative shock. Infect Dis Clin North Am. 1991; 5: 781-791.
2. Giannoudis PV, Smith RM, Bellamy MC, Morrison JF, Dickson RA, Guillou PJ. Stimulation of the inflammatory system by reamed and unreamed nailing of femoral fractures: an analysis of the second hit. J Bone Joint Surg Br. 1999; 81: 356-361.
3. Goris RJ. Mediators of multiple organ failure. Intensive Care Med. 1990; 16 (suppl 3): S192-S196.
4. Cryer HG, Leong K, McArthur DL, et al. Multiple organ failure: by the time you predict it, it's already there. J Trauma. 1999; 46: 597-606.
5. Navarrete-Navarro P, Rodriguez A, Reynolds N, et al. Acute respiratory distress syndrome among trauma patients: trends in ICU mortality, risk factors, complications and resource utilization. Intensive Care Med. 2001; 27: 1133-1140.
6. Lee WL, Downey GP. Neutrophil activation and acute lung injury. Curr Opin Crit Care. 2001; 7: 1-7.
7. Zeiher BG, Matsuoka S, Kawabata K, Repine JE. Neutrophil elastase and acute lung injury: prospects for sivelestat and other neutrophil elastase inhibitors as therapeutics. Crit Care Med. 2002; 30: S281-S287.
8. Shelley SA. Oxidant-induced alterations of lung surfactant system. J Fla Med Assoc. 1994; 81: 49-51.
9. Hamvas A, Palazzo R, Kaiser L, et al. Inflammation and oxygen free radical formation during pulmonary ischemia-reperfusion injury. J Appl Physiol. 1992; 72: 621-628.
10. Strieter RM, Kunkel SL. Acute lung injury: the role of cytokines in the elicitation of neutrophils. J Investig Med. 1994; 42: 640-651.
11. Zimmerman GA, Albertine KH, Carveth HJ, et al. Endothelial activation in ARDS. Chest. 1999; 116: 18S-24S.
12. Yokomura I, Iwasaki Y, Nagata K, et al. Role of intercellular adhesion molecule 1 in acute lung injury induced by candidemia. Exp Lung Res. 2001; 27: 417-431.
13. Sato N, Suzuki Y, Nishio K, et al. Roles of ICAM-1 for abnormal leukocyte recruitment in the microcirculation of bleomycin-induced fibrotic lung injury. Am J Respir Crit Care Med. 2000; 161: 1681-1688.
14. Moss M, Gillespie MK, Ackerson L, Moore FA, Moore EE, Parsons PE. Endothelial cell activity varies in patients at risk for the adult respiratory distress syndrome. Crit Care Med. 1996; 24: 1782-1786.
15. Laffon M, Pittet JF, Modelska K, Matthay MA, Young DM. Interleukin-8 mediates injury from smoke inhalation to both the lung endothelial and the alveolar epithelial barriers in rabbits. Am J Respir Crit Care Med. 1999; 160: 1443-1449.
16. Quinlan GJ, Lamb NJ, Tilley R, Evans TW, Gutteridge JM. Plasma hypoxanthine levels in ARDS: implications for oxidative stress, morbidity, and mortality. Am J Respir Crit Care Med. 1997; 155: 479-484.
17. Meduri GU, Kohler G, Headley S, Tolley E, Stentz F, Postlethwaite A. Inflammatory cytokines in the BAL of patients with ARDS: persistent elevation over time predicts poor outcome. Chest. 1995; 108: 1303-1314.
18. Goodman RB, Strieter RM, Martin DP, et al. Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome. Am J Respir Crit Care Med. 1996; 154: 602-611.
19. Littner MR, Lott FD. Edema from cyclooxygenase products of endogenous arachidonic acid in isolated lung. J Appl Physiol. 1989; 67: 846-855.
20. Gust R, Kozlowski JK, Stephenson AH, Schuster DP. Role of cyclooxygenase-2 in oleic acid-induced acute lung injury. Am J Respir Crit Care Med. 1999; 160: 1165-1170.
21. Abreu MT, Vora P, Faure E, Thomas LS, Arnold ET, Arditi M. Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide. J Immunol. 2001; 167: 1609-1616.
22. Faure E, Equils O, Sieling PA, et al. Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells: differential expression of TLR-4 and TLR-2 in endothelial cells. J Biol Chem. 2000; 275: 11058-11063.
23. Read RC, Wyllie DH. Toll receptors and sepsis. Curr Opin Crit Care. 2001; 7: 371-375.
24. Yang Q, Zhu P, Wang Z, Jiang J. Lipopolysaccharide upregulates the expression of Toll-like receptor 4 in human vascular endothelial cells. Chin Med J (Engl). 2002; 115: 286-289.
25. Ding AH, Porteu F, Sanchez E, Nathan CF. Downregulation of tumor necrosis factor receptors on macrophages and endothelial cells by microtubule depolymerizing agents. J Exp Med. 1990; 171: 715-727.
26. Marczin N, Jilling T, Papapetropoulos A, Go C, Catravas JD. Cytoskeleton-dependent activation of the inducible nitric oxide synthase in cultured aortic smooth muscle cells. Br J Pharmacol. 1996; 118: 1085-1094.
27. Molad Y. Update on colchicine and its mechanism of action. Curr Rheumatol Rep. 2002; 4: 252-256.
28. Maier JA, Hla T, Maciag T. Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells. J Biol Chem. 1990; 265: 10805-10808.
29. Dignam JD. Preparation of extracts from higher eukaryotes. Methods Enzymol. 1990; 182: 194-203.
30. Roebuck KA. Oxidant stress regulation of IL-8 and ICAM-1 gene expression: differential activation and binding of the transcription factors AP-1 and NF-kappaB (review). Int J Mol Med. 1999; 4: 223-230.
31. Manning AM, Bell FP, Rosenbloom CL, et al. NF-kappa B is activated during acute inflammation in vivo in association with elevated endothelial cell adhesion molecule gene expression and leukocyte recruitment. J Inflamm. 1995; 45: 283-296.
32. Mortelliti MP, Manning HL. Acute respiratory distress syndrome. Am Fam Physician. 2002; 65: 1823-1830.
33. Walzog B, Weinmann P, Jeblonski F, Scharffetter-Kochanek K, Bommert K, Gaehtgens P. A role for beta(2) integrins (CD11/CD18) in the regulation of cytokine gene expression of polymorphonuclear neutrophils during the inflammatory response. FASEB J. 1999; 13: 1855-1865.
34. Steeber DA, Tang ML, Green NE, Zhang XQ, Sloane JE, Tedder TF. Leukocyte entry into sites of inflammation requires overlapping interactions between the L-selectin and ICAM-1 pathways. J Immunol. 1999; 163: 2176-2186.
35. Prins BA, Hu RM, Nazario B, et al. Prostaglandin E2 and prostacyclin inhibit the production and secretion of endothelin from cultured endothelial cells. J Biol Chem. 1994; 269: 11938-11944.
36. Caughey GE, Cleland LG, Penglis PS, Gamble JR, James MJ. Roles of cyclooxygenase (COX)-1 and COX-2 in prostanoid production by human endothelial cells: selective up-regulation of prostacyclin synthesis by COX-2. J Immunol. 2001; 167: 2831-2838.
37. Bannerman DD, Goldblum SE. Direct effects of endotoxin on the endothelium: barrier function and injury. Lab Invest. 1999; 79: 1181-1199.
38. Spitzer JH, Visintin A, Mazzoni A, Kennedy MN, Segal DM. Toll-like receptor 1 inhibits Toll-like receptor 4 signaling in endothelial cells. Eur J Immunol. 2002; 32: 1182-1187.
39. Arbabi S, Rosengart MR, Garcia I, Maier RV. Hypertonic saline solution induces prostacyclin production by increasing cyclooxygenase-2 expression. Surgery. 2000; 128: 198-205.
40. Hippenstiel S, Soeth S, Kellas B Rho proteins and the p38-MAPK pathway are important mediators for LPS-induced interleukin-8 expression in human endothelial cells Blood 2000 95 3044-3051.
41. Tamura DY, Moore EE, Johnson JL, Zallen G, Aiboshi J, Silliman CC. p38 mitogen-activated protein kinase inhibition attenuates intercellular adhesion molecule-1 up-regulation on human pulmonary microvascular endothelial cells. Surgery. 1998; 124: 403-408.
42. DeMeester SL, Cobb JP, Hotchkiss RS, et al. Stress-induced fractal rearrangement of the endothelial cell cytoskeleton causes apoptosis. Surgery. 1998; 124: 362-371.
43. Busse R, Fleming I. Molecular responses of endothelial tissue to kinins. Diabetes. 1996; 45 (suppl 2): S8-S13.
44. Dong C, Li Z, Alvarez R Jr., Feng XH, Goldschmidt-Clermont PJ. Microtubule binding to Smads may regulate TGF beta activity. Mol Cell. 2000; 5: 27-34.
45. Platts SH, Falcone JC, Holton WT, Hill MA, Meininger GA. Alteration of microtubule polymerization modulates arteriolar vasomotor tone. Am J Physiol. 1999; 277: H100-H106.
46. Tibbles LA, Ing YL, Kiefer F, et al. MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6. EMBO J. 1996; 15: 7026-7035.
47. Srinivasa SP, Doshi PD. Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways cooperate in mediating cytokine-induced proliferation of a leukemic cell line. Leukemia. 2002; 16: 244-253.
48. Sheth K, Friel J, Nolan B, Bankey P. Inhibition of p38 mitogen activated protein kinase increases lipopolysaccharide induced inhibition of apoptosis in neutrophils by activating extracellular signal-regulated kinase. Surgery. 2001; 130: 242-248.
49. Ding XZ, Adrian TE. MEK/ERK-mediated proliferation is negatively regulated by P38 map kinase in the human pancreatic cancer cell line, PANC-1. Biochem Biophys Res Commun. 2001; 282: 447-453.
50. Whitmarsh AJ, Davis RJ. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. J Mol Med. 1996; 74: 589-607.
51. Kristof AS, Marks-Konczalik J, Moss J. Mitogen-activated protein kinases mediate activator protein-1-dependent human inducible nitric-oxide synthase promoter activation. J Biol Chem. 2001; 276: 8445-8452.
52. An H, Yu Y, Zhang M, et al. Involvement of ERK, p38 and NF-kappaB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells. Immunology. 2002; 106: 38-45.
53. Zhang FX, Kirschning CJ, Mancinelli R, et al. Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J Biol Chem. 1999; 274: 7611-7614.
54. Subbaramaiah K, Hart JC, Norton L, Dannenberg AJ. Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2: evidence for involvement of ERK1/2 and p38 mitogen-activated protein kinase pathways. J Biol Chem. 2000; 275: 14838-14845.
55. Sawyer SJ, Norvell SM, Ponik SM, Pavalko FM. Regulation of PGE(2) and PGI(2) release from human umbilical vein endothelial cells by actin cytoskeleton. Am J Physiol. 2001; 281: C1038-C1045.