Breaking non-native hydrophobic clusters is the rate-limiting step in the folding of an alanine-based peptide

Biopolymers

Volumn 68, Issue 1, 2003, Pages 63-75

  Chowdhury, Shibasish ^a   Zhang, Wei ^a   Wu, Chun ^a   Xiong, Guoming ^a   Duan, Yong ^a  

^a UNIVERSITY OF DELAWARE   (United States)

Author keywords

Alanine based peptide; All atom molecular dynamics; AMBER; Formation mechanism; Generalized Born continuum solvent model; Hydrophobic clusters; Peptide folding; Point charge force field; Protein folding; Rate limiting step

Indexed keywords

HYDROGEN BONDS; HYDROPHOBICITY; MOLECULAR DYNAMICS; SOLVENTS;

HYDROPHOBIC CLUSTERS;

BIOPOLYMERS;

ALANINE; HELIX LOOP HELIX PROTEIN; PEPTIDE;

ARTICLE; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DYNAMICS; MOLECULAR MODEL; PROTEIN FOLDING; VISCOSITY;

EID: 0037234367     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/bip.10216     Document Type: Article

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