Concomitant allorecognition of mismatched donor HLA class I- and class II- derived peptides in pediatric lung transplant recipients with bronchiolitis obliterans syndrome

Journal of Heart and Lung Transplantation

Volumn 22, Issue 1, 2003, Pages 35-43

  Lu, Kim C ^a   Jaramillo, Andrés ^a   Mendeloff, Eric N ^a   Huddleston, Charles B ^a   Sweet, Stuart C ^a   Patterson, G Alexander ^a   Mohanakumar, T ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; HLA DR ANTIGEN; PEPTIDE DERIVATIVE;

ADOLESCENT; ALLOIMMUNITY; ALPHA CHAIN; ANALYSIS; ANTIGEN RECOGNITION; ARTICLE; BETA CHAIN; BLOOD; BRONCHIOLITIS; CELL CULTURE; CHILD; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DILUTION; FREQUENCY ANALYSIS; HISTOCOMPATIBILITY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN VARIABLE REGION; LUNG TRANSPLANTATION; MOLECULE; MONONUCLEAR CELL; OBSERVATION; ORGAN DONOR; PEDIATRIC SURGERY; PEPTIDE SYNTHESIS; POPULATION; PRIORITY JOURNAL; RECIPIENT; T LYMPHOCYTE;

BRONCHIOLITIS OBLITERANS; CD4-POSITIVE T-LYMPHOCYTES; CHILD; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; HISTOCOMPATIBILITY TESTING; HUMANS; ISOANTIBODIES; ISOANTIGENS; LUNG TRANSPLANTATION;

EID: 0037229946     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1053-2498(02)00478-3     Document Type: Article

References (40)

1. Reinsmoen N.L., Bolman R.M., Savik K., Butters K., Hertz M.I. Are multiple immunopathogenic events occurring during the development of obliterative bronchiolitis and acute rejection? Transplantation. 55:1993;1040-1044.
2. Kelly K., Hertz M.I. Obliterative bronchiolitis. Clin Chest Med. 18:1997;319-338.
3. Tullius S.G., Tilney N.L. Both alloantigen-dependent and independent factors influence chronic allograft rejection. Transplantation. 59:1995;313-318.
4. Sundaresan S., Mohanakumar T., Smith M.A., et al. HLA-A locus mismatches and development of antibodies to HLA after lung transplantation correlate with the development of bronchiolitis obliterans syndrome. Transplantation. 65:1998;648-653.
5. van den Berg J.W., Hepkema B.G., Geertsma A., et al. Long-term outcome of lung transplantation is predicted by the number of HLA-DR mismatches. Transplantation. 71:2001;368-373.
6. SivaSai K.S.R., Smith M.A., Poindexter N., et al. Indirect recognition of donor HLA class I peptides in lung transplantation recipients with bronchiolitis obliterans syndrome. Transplantation. 67:1999;1094-1098.
7. Reznik S.I., Jaramillo A., SivaSai K.S.R., et al. Indirect allorecognition of mismatched donor HLA class II peptides in lung transplant recipients with bronchiolitis obliterans syndrome. Am J Transpl. 1:2001;228-235.
8. Smith M.A., Sundaresan R.S., Mohanakumar T., et al. Effect of development of antibodies to HLA and CMV mismatch on lung transplant survival and development of bronchiolitis obliterans syndrome. Am J Thorac Surg. 116:1998;812-820.
9. Jaramillo A., Smith M.A., Phelan D., et al. Development of ELISA-detected anti-HLA antibodies precedes the development of bronchiolitis obliterans syndrome and correlates with progressive decline in pulmonary function after lung transplantation. Transplantation. 67:1999;1155-1161.
10. Jaramillo A., Naziruddin B., Zhang L., et al. Activation of human airway epithelial cells by non-HLA antibodies developed after lung transplantation a potential etiological factor for bronchiolitis obliterans syndrome . Transplantation. 71:2001;966-976.
11. Shoskes D.A., Wood K.J. Indirect presentation of MHC antigens in transplantation. Immunol Today. 15:1994;32-38.
12. Sayegh M.H., Watschinger B., Carpenter C.B. Mechanisms of T cell recognition of alloantigen The role of peptides . Transplantation. 57:1994;1295-1302.
13. Sherman L.A., Chattopadhyay S. The molecular basis of allorecognition. Ann Rev Immunol. 11:1993;385-402.
14. Watschinger B., Gallon L., Carpenter C., Sayegh M. Mechanism of allo-recognition Recognition by in vivo primed T cells of specific major histocompatibility complex polymorphisms presented as peptides by responder antigen-presenting cells . Transplantation. 57:1994;572-576.
15. Gallon L., Watschinger B., Murphy B., Akalin E., Sayegh M.H., Carpenter C.B. The indirect pathway of allorecognition The occurrence of self-restricted T cell recognition of allo-MHC peptides early in acute renal allograft rejection and its inhibition by conventional immunosuppression . Transplantation. 59:1995;612-616.
16. Suciu-Foca N., Reed E., D'Agati V.D., et al. Soluble HLA antigens, anti-HLA antibodies and anti-idiotypic antibodies in the circulation of renal transplant recipients. Transplantation. 51:1991;593-601.
17. Bradley J.A., Mowat A.M., Bolton E.M. Processed MHC class I alloantigen as the stimulus for CD4+ T-cell dependent antibody-mediated graft rejection. Immunol Today. 13:1992;434-438.
18. Liu Z., Sun Y.K., Xi Y.P., et al. Contribution of direct and indirect recognition pathways to T cell alloreactivity. J Exp Med. 177:1993;1643-1650.
19. Lee R.S., Grusby M.J., Glimcher L.H., Winn H.J., Auchincloss H. Jr. Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo. J Exp Med. 179:1994;865-872.
20. Steele D.J., Laufer T.M., Smiley S.T., et al. Two levels of help for B cell alloantibody production. J Exp Med. 183:1996;699-703.
21. Sayegh M.H., Carpenter C.B. Role of indirect allorecognition in allograft rejection. Int Rev Immunol. 13:1996;221-229.
22. Bradley J.A. Indirect T cell recognition in allograft rejection. Intern Rev Immunol. 13:1996;245-255.
23. Parker K.E., Dalchau R., Fowler V.J., Priestley C.A., Carter C.A., Fabre J.W. Stimulation of CD4+ T lymphocytes by allogeneic MHC peptides presented on autologous antigen presenting cells. Transplantation. 53:1992;918-924.
24. Sayegh M.H., Khoury S.J., Hancock W.W., Weiner H.L., Carpenter C.B. Induction of immunity and oral tolerance with polymorphic class II major histocompatibility complex allopeptides in the rat. Proc Natl Acad Sci U S A. 89:1992;7762-7766.
25. Benichou G., Takizawa P.A., Olson C.A., McMillan M., Sercarz E.E. Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection. J Exp Med. 175:1992;305-308.
26. Fangmann J., Dalchau R., Fabre J. Rejection of skin allografts by indirect allorecognition of donor class I major histocompatibility complex peptides. J Exp Med. 175:1992;1521-1529.
27. Benham A.M., Sawyer G.J., Fabre J.W. Indirect T cell allorecognition of donor antigens contributes to the rejection of vascularized kidney allografts. Transplantation. 59:1995;1028-1032.
28. Waaga A.M., Chandraker A., Spadafora-Ferreira M., et al. Mechanisms of indirect allorecognition Characterization of MHC class II allopeptide-specific T helper cell clones from animals undergoing acute allograft rejection . Transplantation. 65:1998;876-883.
29. Pettigrew G.J., Lovegrove E., Bradley J.A., Maclean J., Bolton E.M. Indirect T cell allorecognition and alloantibody-mediated rejection of MHC class I disparate heart grafts. J Immunol. 161:1998;1292-1298.
30. Liu Z., Colovai A.I., Tugulea S., et al. Indirect recognition of donor HLA-DR peptides in organ allograft rejection. J Clin Invest. 98:1996;1150-1157.
31. Liu Z., Harris P.E., Coloval A.I., Reed E.F., Maffei A., Suciu-Foca N. Indirect recognition of donor MHC class II antigens in human transplantation. Clin Immunol Immunopathol. 78:1996;228-235.
32. Vella J.P., Spadafora-Ferreira M., Murphy B., et al. Indirect allorecognition of major histocompatibility complex allopeptides in human renal transplant recipients with chronic graft dysfunction. Transplantation. 64:1997;795-800.
33. Molajoni E.R., Cinti P., Orlandini A., et al. Mechanism of liver allograft rejection the indirect recognition pathway . Human Immunol. 53:1997;57-63.
34. Clubotariu R., Liu Z., Colovai A.I., et al. Persistent allopeptide reactivity and epitope spreading in chronic rejection of organ allografts. J Clin Invest. 101:1998;398-405.
35. Cooper J.D., Billingham M., Egan T., et al. A working formulation for the standardization of nomenclature and for clinical staging of chronic dysfunction in lung allografts International Society for Heart and Lung Transplantation . J Heart Lung Transplant. 12:1993;713-716.
36. Dozmorov I., Eisenbraun M.D., Lefkovits I. Limiting dilution analysis from frequencies to cellular interactions . Immunol Today. 21:2000;15-18.
37. Bonnegoix T., Bonnefoix P., Callanan M., Verdiel P., Sotto J.J. Graphical representation of a generalized linear model-based statistical test estimating the fit of the single-hit Poisson model to limiting dilution assays. J Immunol. 167:2001;5725-5730.
38. Sawyer G.J., Dalchau R., Fabre J.W. Indirect T cell allorecognition a cyclosporin A resistant pathway for T cell help for antibody production to donor MHC antigens . Transplant Immunol. 1:1993;77-81.
39. Clerici M., Shearer G.M. Differential sensitivity of human T helper cell pathways by in vitro exposure to cyclosporin A. J Immunol. 144:1990;2480-2485.
40. Kresnsky A.M., Clayberger C. HLA-derived peptides as novel immunotherapeutics. Clin Immunol Immunopathol. 75:1995;112-116.