Mechanism of liver allograft rejection: The indirect recognition pathway

Human Immunology

Volumn 53, Issue 1, 1997, Pages 57-63

  Molajoni, Elvira Renna ^a   Cinti, Paola ^a   Orlandini, Annamaria ^a   Molajoni, Jacopo ^b   Tugulea, Sorina ^c   Ho, Eric ^c   Liu, Zhuoru ^c   Suciu Foca, Nicole ^c   Cortesini, Raffaello ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b CNR   (Italy)

^c Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN;

ANTIGEN RECOGNITION; ARTICLE; CLINICAL ARTICLE; FEMALE; GRAFT REJECTION; HLA SYSTEM; HUMAN; IMMUNOPATHOGENESIS; LIVER TRANSPLANTATION; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANTIGEN PRESENTATION; EPITOPES; FEMALE; GRAFT REJECTION; HLA-DR ANTIGENS; HUMANS; ISOANTIGENS; LIVER TRANSPLANTATION; MALE; PEPTIDES; PREDICTIVE VALUE OF TESTS; T-LYMPHOCYTES; TRANSPLANTATION, HOMOLOGOUS;

EID: 0030910380     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(97)00029-3     Document Type: Article

References (21)

1. Vierling M. Immunologic mechanisms of hepatic allograft rejection. Sem Liver Dis 12:16, 1992.
2. Hubscher SG. Pathology of liver allograft rejection. Transpl Immunol 2:118, 1994.
3. Nawaz S, Fennell RH. Apoptosis of bile duct epithelial cells in hepatic allograft rejection. Histopathol 25:137, 1994.
4. Lowes JR, Hubscher SG, Neuberger JM. Chronic rejection of the liver allograft. Adv Liver Transpl 22:401, 1993.
5. Krams SM, Falco DA, Villanueva JC, Rabkin J, Tomlanovich SJ, Vincenti F, Amend WJC, Melzer J, Garovoy MR, Roberts JP, Ascher NL, Martinez OM. Cytokine and T cell receptor gene expression at the site of allograft rejection. Transplantation 53:151, 1992.
6. Krams SM, Ascher NL, Martinez OM. New Immunologic insights into mechanisms of allograft rejection. Adv Liver Transpl 22:381, 1993.
7. Knechtle SJ, Wolfe JA, Burchette J, Sanfilippo F, Bollinger RR. Infiltrating cell phenotypes and patterns associated with hepatic allograft rejection or acceptance. Transplantation 43:169, 1987.
8. Fung JJ, Zeevi A, Markus B, Zerbe TR, Duquesnoy RJ. Dynamics of allospecific T lymphocyte infiltration in vascularized human allografts. Immunol Res 5:149, 1986.
9. Halloran PF, Autenried P, Ramassar V, Urmson J, Cock-field S. Local T cell responses induce widespread MHC expression: evidence that IFN-γ induces its own expression remote sites. J Immunol 148:3837, 1992.
10. Fung JJ, Zeevi A, Starzl TE, Demetris J, Iwatsuki S, Duquesnoy RJ. Functional characterization of infiltrating T lymphocytes in human hepatic allografts. Hum Immunol 16:182, 1986.
11. Bradley JA. Indirect T cell recognition in allograft rejection. Intern Rev Immunol 13:245, 1996.
12. Steinman RM, Cohn ZA. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation tissue distribution. J Exp Med 137: 1142, 1973.
13. Steinman RM, Inaba K, Schuler G, Witmer M. Stimula-tion of the immune response: Contribution of dendritic cells. Mechanisms of host resistance to infectious agents, tumors and allografts. In: RM Steinman, RJ North (Eds) New York, Rockefeller University Press, 1986, pp 71.
14. Forbes RD, Parfrey NA, Gomresail M, Darden AG, Guttmann RD. Dendritic cell-lymphoid aggregation and major histocompatibility antigen expression during rat cardiac allograft rejection. J Exp Med 164:1239, 1986.
15. Demetris AJ, Qian S, Sun H, Fung JJ, Yagihashi A, Murase N, Iwaki Y, Gambrell B, Starzl TE. Early events in liver allograft rejection. Am J Pathol 138:609, 1991.
16. Liu Z, Colovai AI, Tugulea S, Reed EF, Fisher PE, Mancini D, Rose EA, Cortesini R, Michler RE, Suciu-Foca N. Indirect recognition of donor HLA-DR peptides in organ allograft rejection. J Clin Invest 98:1150, 1996.
17. McCaughan W, Davies S, Waugh J, Painter D, Gallagher ND, Thompson J, Sheil AGR. Cell surface phenotype of mononuclear cells infiltrating bile ducts during acute and chronic liver allograft rejection. Transplant Proc 21:2201, 1989.
18. Kolbeck PC, Wood RP, Markin RS. The immunopathology and clinical relevance of lymphocyte cultures in liver transplantation. Modern Pathol 6:307, 1993.
19. Farges O, Buffello D, Shi, YM, Berth A, Bismuth H. Anti-donor antibody class switching after liver transplantation. Transplantation 6:296, 1995.
20. Duffy BF, Mathew JM, Flye MW, Mohanakuma T. Development of autoantibodies to T cell clonotypic structures in a liver-kidney allograft recipient. Transplantation 56:212, 1993.
21. Colovai AI, Molajoni ER, Cortesini R, Suciu-Foca N. New approaches to specific immunomodulation in transplantation. Int Rev Immunol 13:161, 1996.