Indirect recognition of donor MHC class II antigens in human transplantation

Clinical Immunology and Immunopathology

Volumn 78, Issue 3, 1996, Pages 228-235

  Liu, Zhuoru ^a   Harris, Paul E ^a   Colovai, Adriana I ^a   Reed, Elaine F ^a   Maffei, Antonella ^a   Suciu Foca, Nicole ^a  

^a The New York Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; INTERLEUKIN 2; SYNTHETIC PEPTIDE;

ARTICLE; CASE REPORT; GRAFT REJECTION; HEART TRANSPLANTATION; HELPER CELL; HUMAN; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0029979561     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1996.0034     Document Type: Article

References (29)

1. Sherman, L. A., and Chattopadhyan, S., The molecular basis of allorecognition. Annu. Rev. Immunol. 11, 385-402, 1993.
2. Shoskes, D. A., and Wood, K. J., Indirect presentation of MHC antigens in transplantation. Immunol. Today 15, 32-38, 1994.
3. Suciu-Foca, N., Reed, E., D'Agati, V. D., Ho, E., Cohen, D. J., Benvenisty, A. I., McCabe, R., Brensilver, J. M., King, D. W., and Hardy, M. A., Soluble HLA antigens, anti-HLA antibodies and anti-idiotypic antibodies in the circulation of renal transplant recipients. Transplantation 51, 593-601, 1991.
4. Suciu-Foca, N., Reed, E., Marboe, C., Xi, Y. P., Sun, Y. K., Ho, E., Rose, E. A., Reemtsma, K., and King, D. W., Role of anti-HLA antibodies in heart transplantation. Transplantation 51, 716-724, 1991.
5. Lee, R. S., Grusby, M. J., Glimcher, L. H., Winn, H. J., and Auchincloss, Jr., H., Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo. J. Exp. Med. 179, 865-872, 1994.
6. Benichou, G., Takizawa, P. A., Olson, C. A., McMillan, M., and Sercarz, E. E., Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection. J. Exp. Med. 175, 305-308, 1992.
7. Fangmann, J., Dalchau, R., and Fabre, J. W., Rejection of skin allografts by indirect allorecognition of donor class I major histocompatibility complex peptides. J. Exp. Med. 175, 1521-1529, 1992.
8. Dalchau, R., Fangmann, J., and Fabre, J. W., Allorecognition of isolated, denatured chains of class I and class II major histocompatibility complex molecules. Evidence for an important role for indirect allorecognition in transplantation. Eur. J. Immunol. 22, 669-677, 1992.
9. + T lymphocytes by allogeneic MHC peptides presented on autologous antigenpresenting cells. Evidence of the indirect pathway of allorecognition in some strain combinations. Transplantation 53, 918-924, 1992.
10. Sayegh, M. H., Khoury, S. J., Hancock, W. W., Weiner, H. L., and Carpenter, C. B., Induction of immunity and oral tolerance with polymorphic class II major histocompatibility complex allopeptides in the rat. Proc. Natl. Acad. Sci. USA 89, 7762-7766, 1992.
11. Gallon, L., Watschinger, B., Murphy, B., Akalin, E., Sayegh, M. H., and Carpenter, C. B., The indirect pathway of allorecognition. Transplantation 59, 612-616, 1995.
12. de Koster, H. S., Anderson, D. C., and Termijtelen, A., T cells sensitized to synthetic HLA-DR3 peptide give evidence of continuous presentation of denatured HLA-DR3 molecules by HLA-DP. J. Exp. Med. 169, 1191-1196, 1989.
13. Chen, B. P., Madrigal, A., and Parham, P., Cytotoxic T cell recognition of an endogenous class I HLA peptide presented by a class II HLA molecule. J. Exp. Med. 172, 779-788, 1990.
14. Liu, Z., Braunstein, N., and Suciu-Foca, N., T cell recognition of allopeptides in context of syngeneic MHC. J. Immunol. 148, 35-40, 1992.
15. Liu, Z., Sun, Y. K., Xi, Y. P., Maffei, A., Reed, E., Harris, P. E., and Suciu-Foca, N., Contribution of direct and indirect recognition pathway to T cell alloreactivity. J. Exp. Med. 177, 1643-1650, 1993.
16. Liu, Z., Sun, Y. K., Xi, Y. P., Hong, B., Harris, P. E., Reed, E., and Suciu-Foca, N., Limited usage of TCR Vβ genes by allopeptide specific T cells. J. Immunol. 150, 3180-3186, 1993.
17. Winters, G. L., The pathology of heart allograft rejection. Arch. Pathol. Lab. Med. 115, 269-273, 1991.
18. Bell, J. I., Denney, D., Foster, L., Belt, T., Todo, J. A., and McDevitt, H. O., Allelic variation in the DR subregion of the human major histocompatibility complex. Proc. Natl. Acad. Sci. USA 84, 6234-6266, 1989.
19. Sheirle, A., Takacs, B., Kremer, L., Marin, F., and Sinigaglia, F., Peptide binding to soluble HLA-DR4 molecules produced by insect cells. J. Immunol. 149, 1994-1999, 1992.
20. Harris, P. E., Liu, Z., and Suciu-Foca, N., MHC class II binding of peptides derived from HLA-DR1. J. Immunol. 148, 2169-2176, 1992.
21. Zhang, J., Markovic-Leese, S., Lacet, B., Raus, F., Weiner, H. L., and Hafler, D. A., Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. J. Exp. Med. 179, 973-984, 1994.
22. Suzuki, G., Kawase, Y., Koyasu, S., Yahara, L., Kobayashi, Y., and Schwartz, R. H., Antigen-induced suppression of the proliferative response of T cell clones. J. Immunol. 140, 1359-1365, 1988.
23. Critchfield, J. M., Racke, M. K., Zuniga-Pflucker, J. C., Cannella, B., Raine, C. S., Goverman, J., and Lenardo, M. J., T Cell deletion in high antigen dose therapy of autoimmune encephalomyelitis. Science 263, 1139-1143, 1994.
24. Sercarz, E. E., Lehmann, P. V., Ametani, A., Benichou, G., Miller, A., and Moudgil, K., Dominance and crypticity of T cell antigenic determinants. Annu. Rev. Immunol. 11, 729-766, 1993.
25. Benichou, G., Fedoseyeva, E., Lehmann, P. V., Olson, C. A., Geysen, H. M., McMillan, M., and Sercarz, E. E., Limited T cell response to donor MHC peptides during allograft rejection: Implications for selective immune therapy in transplantation. J. Immunol. 153, 938-938, 1994.
26. Lechler, R. I., and Batchelor, J. R., Restoration of immunogenicity to passenger cell depleted kidney allografts by the addition of donor strain dendritic cells. J. Exp. Med. 155, 31-41, 1982.
27. Howell, M. D., Winters, S. T., Olee, T., Powell, H. D., Carlo, D. J., and Brosstoff, S. W., Vaccination against experimental allergic encephalomyelitis with T cell receptor peptides. Science 246, 668-670, 1989.
28. Vandenbark, A. A., Hashim, G., and Offner, H., Immunization with a synthetic T cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis. Nature 341, 541-544, 1989.
29. Kresnsky, A. M., and Clayberger, C., HLA-derived peptides as novel immunotherapeutics. Clin. Immunol. Immunopathol. 75, 112-116, 1995.