Prostaglandin D2 synthase enzymes and PPARγ are co-expressed in mouse 3T3-L1 adipocytes and human tissues

Prostaglandins and Other Lipid Mediators

Volumn 70, Issue 3-4, 2003, Pages 267-284

  Jowsey, Ian R ^a   Murdock, Paul R ^b   Moore, Gary B T ^b   Murphy, Gregory J ^b   Smith, Stephen A ^b   Hayes, John D ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Adipose tissue; Nuclear receptor; Prostaglandin

Indexed keywords

GLUTATHIONE; ISOENZYME; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN D2; PROSTAGLANDIN SYNTHASE; CELL RECEPTOR; ISOMERASE; LIGAND; PRIMER DNA; PROSTAGLANDIN R2 D ISOMERASE; PROSTAGLANDIN R2 D-ISOMERASE; TRANSCRIPTION FACTOR;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL TYPE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MACROPHAGE; MALE; MOLECULAR BIOLOGY; NONHUMAN; PLACENTA; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROSTATE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL LINE; CELL STRAIN 3T3; CYTOLOGY; METABOLISM; MOUSE; SIGNAL TRANSDUCTION; TIME; TISSUE DISTRIBUTION;

3T3 CELLS; ADIPOCYTES; ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLUTATHIONE; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; LIGANDS; MICE; MODELS, BIOLOGICAL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TIME FACTORS; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS;

EID: 0037225497     PISSN: 00906980     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0090-6980(02)00134-X     Document Type: Article

References (58)

1. Rangwala S.M., Lazar M.A. Transcriptional control of adipogenesis. Annu. Rev. Nutr. 20:2000;535.
2. Rosen E.D., Spiegelman B.M. Molecular regulation of adipogenesis. Annu. Rev. Cell. Dev. Biol. 16:2000;145.
3. Zhu Y., Qi C., Korenberg J.R.et al. Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: alternative promoter use and different splicing yield two mPPAR gamma isoforms. Proc. Natl. Acad. Sci. U.S.A. 92:1995;7921.
4. Fajas L., Auboeuf D., Raspe E.et al. The organization, promoter analysis, and expression of the human PPAR gamma gene. J. Biol. Chem. 272:1997;18779.
5. Tontonoz P., Hu E., Spiegelman B.M. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell. 79:1994;1147.
6. Wright H.M., Clish C.B., Mikami T.et al. A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation. J. Biol. Chem. 275:2000;1873.
7. Camp H.S., Chaudhry A., Leff T. A novel potent antagonist of peroxisome proliferator-activated receptor gamma blocks adipocyte differentiation but does not revert the phenotype of terminally differentiated adipocytes. Endocrinology. 142:2001;3207.
8. Gurnell M., Wentworth J.M., Agostini M.et al. A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma-mediated adipogenesis. J. Biol. Chem. 275:2000;5754.
9. Barak Y., Nelson M.C., Ong E.S.et al. PPAR gamma is required for placental, cardiac, and adipose tissue development. Mol. Cell. 4:1999;585.
10. Rosen E.D., Sarraf P., Troy A.E.et al. PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro. Mol. Cell. 4:1999;611.
11. 2 is a ligand for the adipocyte determination factor PPAR gamma. Cell. 83:1995;803.
12. Lehmann J.M., Moore L.B., Smith-Oliver T.A., Wilkison W.O., Willson T.M., Kliewer S.A. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J. Biol. Chem. 270:1995;12953.
13. 2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell. 83:1995;813.
14. Maxey K.M., Hessler E., MacDonald J., Hitchingham L. The nature and composition of 15-deoxy-delta(12,14) PGJ(2). Prostaglandins Other Lipid Mediat. 62:2000;15.
15. Vane J.R., Bakhle Y.S., Botting R.M. Cyclooxygenases 1 and 2. Annu. Rev. Pharmacol. Toxicol. 38:1998;97.
16. Urade Y., Watanabe K., Hayaishi O. Prostaglandin D, E, and F synthases. J. Lipid Mediat. Cell Signal. 12:1995;257.
17. 2. Identification of products formed in vitro. J. Biol. Chem. 258:1983;11713.
18. 2 formed in human plasma. Proc. Natl. Acad. Sci. U.S.A. 81:1984;1317.
19. Urade Y., Hayaishi O. Prostaglandin D synthase: structure and function. Vitam. Horm. 58:2000;89.
20. Urade Y., Hayaishi O. Biochemical, structural, genetic, physiological, and pathophysiological features of lipocalin-type prostaglandin D synthase. Biochim. Biophys. Acta. 1482:2000;259.
21. Meyer D.J., Thomas M. Characterization of rat spleen prostaglandin H D-isomerase as a sigma-class GSH transferase. Biochem. J. 311:1995;739.
22. Kanaoka Y., Ago H., Inagaki E.et al. Cloning and crystal structure of hematopoietic prostaglandin D synthase. Cell. 90:1997;1085.
23. 2 synthase, a novel class Sigma glutathione S-transferase. Biochem. J. 333:1998;317.
24. 2 synthases. Biochem. J. 359:2001;507.
25. Eguchi N., Minami T., Shirafuji N.et al. Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 96:1999;726.
26. Pinzar E., Kanaoka Y., Inui T., Eguchi N., Urade Y., Hayaishi O. Prostaglandin D synthase gene is involved in the regulation of non-rapid eye movement sleep. Proc. Natl. Acad. Sci. U.S.A. 97:2000;4903.
27. Kanaoka Y., Fujimori K., Kikuno R., Sakaguchi Y., Urade Y., Hayaishi O. Structure and chromosomal localization of human and mouse genes for hematopoietic prostaglandin D synthase. Conservation of the ancestral genomic structure of sigma-class glutathione S-transferase. Eur. J. Biochem. 267:2000;3315.
28. Mandrup S., Sorensen R.V., Helledie T.et al. Inhibition of 3T3-L1 adipocyte differentiation by expression of acyl-CoA-binding protein antisense RNA. J. Biol. Chem. 273:1998;23897.
29. Ramirez-Zacarias J.L., Castro-Munozledo F., Kuri-Harcuch W. Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil Red O. Histochemistry. 97:1992;493.
30. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248.
31. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680.
32. Ellis E.M., Judah D.J., Neal G.E., O'Connor T., Hayes J.D. Regulation of carbonyl-reducing enzymes in rat liver by chemoprotectors. Cancer Res. 56:1996;2758.
33. Yokoyama C., Tanabe T. Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme. Biochem. Biophys. Res. Commun. 165:1989;888.
34. Fletcher B.S., Kujubu D.A., Perrin D.M., Herschman H.R. Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase. J. Biol. Chem. 267:1992;4338.
35. Holland P.M., Abramson R.D., Watson R., Gelfand D.H. Detection of specific polymerase chain reaction product by utilizing the 5′-3′ exonuclease activity of Thermus aquaticus DNA polymerase. Proc. Natl. Acad. Sci. U.S.A. 88:1991;7276.
36. Heid C.A., Stevens J., Livak K.J., Williams P.M. Real time quantitative PCR. Genome Res. 6:1996;986.
37. Cornelius P., MacDougald O.A., Lane M.D. Regulation of adipocyte development. Annu. Rev. Nutr. 14:1994;99.
38. MacDougald O.A., Lane M.D. Transcriptional regulation of gene expression during adipocyte differentiation. Annu. Rev. Biochem. 64:1995;345.
39. Cook K.S., Min H.Y., Johnson D.et al. Adipsin: a circulating serine protease homolog secreted by adipose tissue and sciatic nerve. Science. 237:1987;402.
40. Sakaue H., Ogawa W., Matsumoto M.et al. Posttranscriptional control of adipocyte differentiation through activation of phosphoinositide 3-kinase. J. Biol. Chem. 273:1998;28945.
41. O'Neill G.P., Ford-Hutchinson A.W. Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett. 330:1993;156.
42. Eguchi Y., Eguchi N., Oda H.et al. Expression of lipocalin-type prostaglandin D synthase (beta-trace) in human heart and its accumulation in the coronary circulation of angina patients. Proc. Natl. Acad. Sci. U.S.A. 94:1997;14689.
43. Berger J., Moller D.E. The mechanisms of action of PPARs. Annu. Rev. Med. 53:2002;409.
44. Moore K.J., Fitzgerald M.L., Freeman M.W. Peroxisome proliferator-activated receptors in macrophage biology: friend or foe? Curr. Opin. Lipidol. 12:2001;519.
45. Tarrade A., Schoonjans K., Guibourdenche J.et al. PPAR gamma/RXR alpha heterodimers are involved in human CG beta synthesis and human trophoblast differentiation. Endocrinology. 142:2001;4504.
46. Asakawa M., Takano H., Nagai T.et al. Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo. Circulation. 105:2002;1240.
47. Heneka M.T., Klockgether T., Feinstein D.L. Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo. J. Neurosci. 20:2000;6862.
48. Ikai K., Ujihara M., Fujii K., Urade Y. Inhibitory effect of tranilast on prostaglandin D synthetase. Biochem. Pharmacol. 38:1989;2673.
49. Matsushita N., Hizue M., Aritake K.et al. Pharmacological studies on the novel antiallergic drug HQL-79: I. Antiallergic and antiasthmatic effects in various experimental models. Jpn. J. Pharmacol. 78:1998;1.
50. Matsushita N., Aritake K., Takada A.et al. Pharmacological studies on the novel antiallergic drug HQL-79: II. Elucidation of mechanisms for antiallergic and antiasthmatic effects. Jpn. J. Pharmacol. 78:1998;11.
51. 2 alpha inhibits the differentiation of adipocyte precursors in primary culture. Biochem. Biophys. Res. Commun. 183:1992;438.
52. Casimir D.A., Miller C.W., Ntambi J.M. Preadipocyte differentiation blocked by prostaglandin stimulation of prostanoid FP2 receptor in murine 3T3-L1 cells. Differentiation. 60:1996;203.
53. Reginato M.J., Krakow S.L., Bailey S.T., Lazar M.A. Prostaglandins promote and block adipogenesis through opposing effects on peroxisome proliferator-activated receptor gamma. J. Biol. Chem. 273:1998;1855.
54. Rossi A., Kapahi P., Natoli G.et al. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature. 403:2000;103.
55. 2 inhibits multiple steps in the NF-kappa B signaling pathway. Proc. Natl. Acad. Sci. U.S.A. 97:2000;4844.
56. 2-induced expression of glutathione S-transferases. J. Biol. Chem. 275:2000;11291.
57. 2 is mediated by the stress response elements and transcription factor nrf2. Antioxid. Redox Signal. 4:2002;249.
58. Ma H., Sprecher H.W., Kolattukudy P.E. Estrogen-induced production of a peroxisome proliferator-activated receptor (PPAR) ligand in a PPARgamma-expressing tissue. J. Biol. Chem. 273:1998;30131.