Laminin γ2-chain fragment in the circulation: A prognostic indicator of epithelial tumor invasion

Cancer Research

Volumn 63, Issue 1, 2003, Pages 222-229

  Katayama, Masahiko ^a   Sanzen, Noriko ^c,d   Funakoshi, Akihiro ^b   Sekiguchi, Kiyotoshi ^c,d   Fukushima, Yuji ^e  

^a EISAI CO LTD   (Japan)

^b NATIONAL KYUSHU CANCER CENTER   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e OSAKA CENTER FOR CANCER AND CARDIOVASCULAR DISEASE PREVENTION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LAMININ; LAMC2 PROTEIN, HUMAN; LAMC2 PROTEIN, MOUSE; PEPTIDE FRAGMENT; TUMOR MARKER;

AMINO TERMINAL SEQUENCE; ARTICLE; BASEMENT MEMBRANE; CANCER INVASION; CANCER PATIENT; CELL MOTILITY; CHEMOLUMINESCENCE; EPITHELIUM TUMOR; EXTRACELLULAR MATRIX; HEMIDESMOSOME; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; SOLUBILIZATION; ADENOCARCINOMA; ANIMAL; BLOOD; CELL MOTION; FIBROSARCOMA; GLIOBLASTOMA; MOUSE; NUDE MOUSE; PANCREAS TUMOR; PHYSIOLOGY; XENOGRAFT;

ADENOCARCINOMA; ANIMALS; CELL MOVEMENT; FIBROSARCOMA; GLIOBLASTOMA; HUMANS; LAMININ; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; PANCREATIC NEOPLASMS; PEPTIDE FRAGMENTS; PROGNOSIS; TRANSPLANTATION, HETEROLOGOUS; TUMOR MARKERS, BIOLOGICAL;

EID: 0037207873     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Timple, R., and Brown, J. C. The laminins. Matrix Biol., 14: 275-281, 1994.
2. Colognato, H., and Yurchenco, P. D. Form and function: the laminin family of heterotrimers. Dev. Dyn., 218: 213-234, 2000.
3. Rousselle, P., Lunstrum, G. P., Keene, D. R., and Burgeson, R. E. Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments. J. Cell Biol., 114: 567-576, 1991.
4. Carter, W. G., Ryan, M. C., and Gahr, P. J. Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes. Cell. 65: 599-610, 1991.
5. Marinkovich, M. P., Lunstrum, G. P., and Burgeson, R. E. The anchoring filament protein kalinin is synthesized and secreted as a high molecular weight precursor. J. Biol. Chem., 267: 17900-17906, 1992.
6. Giannelli, G., Falk-Marzillier, J., Schiraldi, O., Stetler-Stevenson, W. G., and Quaranta. V. Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. Science (Wash. DC), 277: 225-228, 1997.
7. Koshikawa, N., Giannelli, G., Cirulli, V., Miyazaki, K., and Quaranta, V. Role of cell surface metalloprotease MT-1-MMP in epithelial cell migration over laminin-5. J. Cell Biol., 148: 615-624, 2000.
8. Amano, S., Scott, I. C., Takahara, K., Koch, M., Champliaud, M-F., Gerecke, D. R., Keene, D. R., Hudson, D. L., Nishiyama, T., Lee, S., Greenspan, D. S., and Burgeson, R. E. Bone morphogenetic protein I is an extracellular processing enzyme of the laminin 5 γ2 chain. J. Biol. Chem., 275: 22728-22735. 2000.
9. Lohi, J. Laminin-5 in the progression of carcinomas. Int. J. Cancer, 94: 763-767, 2001.
10. Miyazaki, K., Kikkawa, Y., Nakamura, A., Yasumitsu, H., and Umeda, M. A large cell-adhesive scatter factor secreted by human gastric carcinoma cells. Proc. Natl. Acad. Sci. USA, 90: 11767-11771, 1993.
11. Fukushima, Y., Ohnishi, T., Arita, N., Hayakawa, T., and Sekiguchi, K. Integrin α3β1-mediated interaction with laminin-5 stimulates adhesion, migration, and invasion of malignant glioma cells. Int. J. Cancer. 76: 63-72, 1998.
12. Pyke, C., Rømer, J. Kallunki, P., Lund, L. R., Ralfkizer, E., Danø, K., and Tryggvason, K. The γ2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers. Am. J. Path., 145: 782-791, 1994.
13. Pyke, C., Salo, S., Ralfkiær, E., Rømer, J., Danø, K., and Tryggvason, K. Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas. Cancer Res., 55: 4132-4139, 1995.
14. Ono, Y., Nakanishi, Y., Ino, Y., Niki, T., Yamada, T., Yoshimura, K., Saikawa, M., Nakajima, T., and Hirohashi, S. Clinicopathologic significance of laminin-5 γ2 chain expression in squamous cell carcinoma of the tongue. Cancer (Phila.). 85: 2315-2321, 1999.
15. Skyldberg, B., Salo, S., Eriksson, E., Aspenblad, U., Moberger, B., Tryggvason, K., and Auer, G. Laminin-5 as a marker of invasiveness in cervical lesions, J. Natl. Cancer Inst., 91: 1882-1887, 1999.
16. Koshikawa, N., Moriyama, K., Takamura, H., Mizushima, H., Nagashima, Y., Yanoma, S., and Miyazaki, K. Overexpression of laminin γ2 chain monomer in invading gastric carcinoma cells. Cancer Res., 59: 5596-5601, 1999.
17. Hlubek, F., Jung, A., Kotzor, N., Kirchner, T., and Brabletz, T. Expression of the invasion factor laminin γ2 in colorectal carcinomas is regulated by β-catenin. Cancer Res., 61: 8089-8093, 2001.
18. Amano, S., Nishiyama, T., and Burgeson, R. E. A specific and sensitive ELISA for laminin-5, J. Immunol. Methods, 224: 161-169, 1999.
19. Mercurio, A. M., Rabinovitz, I., and Shaw, L. M. The α6β4 integrin and epithelial cell migration, Curr. Opin. Cell Biol., 13: 541-545, 2001.
20. Giannelli, G., and Antonaci, S, Biological and clinical relevance of laminin-5 in cancer. Clin. Exp. Metast., 18: 439-443, 2001.
21. Jimi, S., Shono, T., Tanaka, M., Kono, A., Yamada, Y., Shudo, K., and Kuwano, M. Effect of retinoic acid on morphological changes of human pancreatic cancer cells on collagen gels: a possible association with the metastatic potentials. Oncol. Res., 10: 7-14, 1998.
22. Harlow, E., and Lane, D. Antibodies: A Laboratory Manual. New York: Cold Spring Harbor Laboratory Press, 1988.
23. Katayama, M., Kamihagi, K., Hirai, S., Kurome, T., Murakami, K., Hino. F., and Kato, I. Urinary laminin fragments as a tumour marker potentially reflecting basement membrane destruction. Br. J. Cancer, 65: 509-514, 1992.
24. Namba, Y., Usami, M., and Suzuki, O. Highly sensitive electrochemiluminescence immunoassay using the Ruthenium chelate-labeled antibody bound on the magnetic micro beads. Ana. Sci., 15: 1087-1093, 1999.
25. Funahashi, Y., Koyanagi, N., Sonoda, J., Kitoh, K., and Yoshimatsu, K. Rapid development of hepatic metastasis with high incidence following orthotopic transplantation of murine colon 38 carcinoma as intact tissue in syngeneic C57BL/6 mice. J. Surg. Oncol., 71: 83-90, 1999.
26. Zervos, E. E., Norman, J. G., Gower, W. R., Franz, M. G., and Rosemurgy, A. S. Matrix metalloproteinase inhibition attenuates human pancreatic cancer growth in vitro and decreases mortality and tumorigenesis in vivo. J. Surg. Res., 69: 367-371, 1997.
27. Mizushima. H., Miyagi, Y., Kikkawa, Y., Yamanaka, N., Yasumitsu, H., Misugi, K., and Miyazaki, K. Differential expression of laminin-5/ladsin subunits in human tissues and cancer cell lines and their induction by tumor promoter and growth factors. J. Biochem., 120: 1196-1202, 1996.
28. Stamenkovic, I. Matrix metalloproteinases in tumor invasion and metastasis, Semin. Cancer Biol., 10: 415-433, 2000.
29. Miyamoto, K. K., McSherry, S. A., Robins, S. P., Besterman, J. M., and Hohler, J. L. Collagen cross-link metabolites in urine as markers of bone metastases in prostatic carcinoma. J. Urol., 151: 909-913, 1994.
30. Feldman, A. L., Tamarkin, L., Paciotti, G. F., Simpson, B. W., Linehan, W. M., Yang, J. C., Fogler, W, E., Turner. E. M., Alexander, H. R., Jr., and Libutti, S. K. Serum endostatin levels are elevated and correlate with serum vascular endothelial growth factor levels in patients with stage IV clear cell renal cancer. Clin. Cancer Res., 6: 4628-4634, 2000.
31. Brocks, D. G., Strecker, H., Neubauer, H. P., and Timple, R. Radioimmunoassay of laminin in serum and its application to cancer patients. Clin. Chem., 32: 787-791, 1986.
32. Byers, L. J., Osborne, J. L., Carson, L. F., Carter, J. R., Haney, A. F., Weinberg, J. B., and Ramakrishnan, S. Increased levels of laminin in ascitic fluid of patients with ovarian cancer. Cancer Lett., 88: 67-72, 1995.
33. Matsui, C., Wang, C. K., Nelson. C. F., Bauer, E. A., and Hoeffler, W. K. The assembly of laminin-5 subunits. J. Biol. Chem., 270: 23496-23503, 1995.
34. Gilles, C., Polette, M., Coraux. C., Tournier, J-M., Meneguzzi, G., Munaut, C., Volders, L., Rousselle, P., Birembaut, P., and Foidart, J-M. Contribution of MTI-MMP and of human laminin-5 γ2 chain degradation to mammary epithelial cell migration. J. Cell Sci., 114: 2967-2976, 2001.
35. Martin, K. J., Kwan, C-P., Nagasaki, K., Zhang, X., O'Hare, M. J., Kaelin, C. M., Burgeson, R. E., Pardee, A. B., and Sager, R. Down-regulation of laminin-5 in breast carcinoma cells. Mol. Med., 4: 602-613, 1998.
36. Rabinovitz, L. Gipson, I. K., and Mercurio, A. M. Traction forces mediated by α6β4 integrin: implications for basement membrane organization and tumor invasion. Mol. Biol. Cell, 12: 4030-4043, 2001.
37. Haberem-Blood, C., Liotta, L. A., Rao, C. N., and Kupchik, H. Z. Laminin expression by human pancreatic carcinoma cells in the nude mouse and in culture. J. Natl. Cancer Inst., 79: 891-897, 1987.
38. Sordat, I., Rousselle, P., Chaubert. P., Petermann, O., Aberdam, D., Bosman, F. T., and Sordat, B. Tumor cell budding and laminin-5 expression in colorectal carcinoma can be modulated by the tissue micro-environment. Int. J. Cancer, 88: 708-717, 2000.
39. Utani, A., Nomizu, M., and Yamada, Y. Fibulin-2 binds to the short arms of laminin-5 and laminin-1 via conserved amino acid sequences. J. Biol. Chem., 272: 2814-2820, 1997.
40. Rousselle, P., Keene, D. R., Ruggiero, F., Champliaud, M-F., van der Rest, M., and Burgeson. R. E. Laminin-5 binds the NC-1 domain of type VII collagen. J. Cell Biol., 138: 719-728, 1997.
41. Sasaki. T., Göhring, W., Mann, K., Brakebusch. C., Yamada, Y., Fässler, R., and Timple, R. Short arm region of laminin-5 γ2 chain: structure, mechanism of processing and binding to heparin and proteins. J. Mol. Biol., 314: 751-763, 2001.
42. Tani, T., Lumme, A., Linnala, A., Kivilaakso, E., Kiviluoto, T., Burgeson, R. E., Kangas, L., Leivo, L. and Virtanen, I. Pancreatic carcinomas deposit laminin-5, preferably adhere to laminin-5, and migrate on the newly deposited basement membrane. Am. J. Pathol., 151: 1289-1302, 1997.
43. Soini, Y., Määtä, M., Salo, S., Tryggvason, K., and Autio-Harmainen, H. Expression of the laminin γ2 chain in pancreatic adenocarcinoma. J. Pathol., 180: 290-294, 1996.