Rapid development of hepatic metastasis with high incidence following orthotopic transplantation of murine Colon 38 carcinoma as intact tissue in syngeneic C57BL/6 mice

Journal of Surgical Oncology

Volumn 71, Issue 2, 1999, Pages 83-90

  Funahashi, Yasuhiro ^a   Koyanagi, Nozomu ^a   Sonoda, Jiro ^a   Kitoh, Kyosuke ^a   Yoshimatsu, Kentaro ^a  

^a EISAI CO LTD   (Japan)

Author keywords

Hepatic metastasis; Intact tissue; Murine Colon 38 carcinoma; Orthotopic transplantation; Syngeneic mice

Indexed keywords

CISPLATIN; FLUOROURACIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; CANCER CHEMOTHERAPY; COLON CARCINOMA; CONTROLLED STUDY; FEMALE; HISTOLOGY; INTRAVENOUS DRUG ADMINISTRATION; ISOGRAFT; LIVER METASTASIS; LUNG METASTASIS; METASTASIS; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PERITONEUM METASTASIS; PRIORITY JOURNAL; TUMOR GROWTH;

ADENOCARCINOMA; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; CISPLATIN; COLONIC NEOPLASMS; FEMALE; FLUOROURACIL; HUMANS; LIVER NEOPLASMS; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; PERITONEAL NEOPLASMS; TRANSPLANTATION, ISOGENEIC;

EID: 0033067017     PISSN: 00224790     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9098(199906)71:2<83::AID-JSO5>3.0.CO;2-5     Document Type: Article

References (19)

1. Schackert HK, Fidler IJ: Development of an animal model to study the biology of recurrent colorectal cancer originating from mesenteric lymph system metastases. Int J Cancer 1989;44:177-181.
2. Fidler IJ: Critical factors in the biology of human cancer metastasis: Twenty-eighth G.H.A. Clowes Memorial Award Lecture. Cancer Res 1990;50:6130-6139.
3. Tan MH, Holyoke ED, Goldrosen MH: Murine colon adenocarcinoma: Syngeneic orthotopic transplantation and subsequent hepatic metastases. J Natl Cancer Inst 1977;59:1537-1544.
4. Morikawa K, Walker SM, Nakajima M, et al.: Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice. Cancer Res 1988;48:6863-6871.
5. Naito S, von Eschenbach AC, Giavazzi R, et al.: Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice. Cancer Res 1986;46:4109-4115.
6. Price JE, Polyzos A, Zhang R, et al.: Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res 1990;50:717-721.
7. Ahlering TE, Dubeau L, Jones PA: A new in vivo model to study invasion and metastasis of human bladder carcinoma. Cancer Res 1996;47:6660-6665.
8. Tan MH, Chu TM: Characterization of the tumorigenic and metastatic properties of a human pancreatic tumor cell line (ASPC-1) implanted orthotopically into nude mice. Tumour Biol 1985;6:89-98.
9. McLemore TL, Liu MC, Blacker PC, et al.: Novel intrapulmonary model for orthotopic progagation of human lung cancers in athymic nude mice. Cancer Res 1987;47:5132-5140.
10. Fidler IJ: Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis. Cancer Metastasis Rev 1991;10:229-243.
11. Fu X, Besterman JM, Monosov A, et al.: Models of human metastatic colon cancer in nude mice orthotopically constricted by using histologically intact patient specimens. Proc Natl Acad Sci USA 1991;88:9345-9349.
12. Hoffman RM: Fertile seed and rich soil: The development of clinically relevant models of human cancer by surgical orthotopic implantation of intact tissue. In Teicher BA (ed): "Cancer Drug Discovery and Development 1, Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and Approval." Totowa, NJ: Humana Press, 1997:127-144.
13. Wang H, Brown PD, Crimmin MJ, et al.: Matrix metalloproteinase inhibitor BB-94 (Batimastat) inhibits human colon tumor growth and spread in a patient-like orthotopic model in nude mice. Cancer Res 1994;54:4726-4728.
14. Richie JP, McDonald BS, Gittes RF: Resistance to intravenous tumor metastases in the athymic nude mouse: A paradoxic response. Surgery 1981;90:214-220.
15. Holzman D: Of mice and metastasis: A new for-profit model emerges. J Natl Cancer Inst 1996;88:396-397.
16. Clark EA, Russell PH, Egghart M, et al.: Characteristics and genetic control of NK-cell-mediated cytotoxicity activated by naturally acquired infection in the mouse. Int J Cancer 1979;24:688-699.
17. Corbett TH, Griswold DP, Roberts BJ, et al.: Tumor induction relationships in development of transplantable cancers of colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res 1975;35:2434-2439.
18. Floyd CE, Stirling CT, Cohn I: Cancer of the colon, rectum and anus: Review of 1,687 cases. Ann Surg 1966;163:829-837.
19. Wilmanns C, Fan D, O'Brian CA, et al.: Orthotopic and ectopic organ environments differentially influence the sensitivity of murine colon carcinoma cells to doxorubicin and 5-fluoroouracil. Int J Cancer 1992;52:98-104.