Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the expression of synaptic proteins in dissociated rat cortical cells

Molecules and Cells

Volumn 14, Issue 2, 2002, Pages 238-244

  Cho, Sun Jung ^b   Jung, Jae Seob ^b   Jin, Ingnyol ^b   Jung, Yong Wook ^a   Ko, Bok Hyun ^a   Nam, Kyung Soo ^a   Park, In Kook ^c   Moon, Il Soo ^a  

^a Dongguk University College of Medicine   (South Korea)

^b Kyungpook National University   (South Korea)

^c Dongguk University   (South Korea)

Author keywords

Cortical Cell Culture; Cytotoxicity; NMDA Receptor; Synaptic Proteins; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; N METHYL DEXTRO ASPARTIC ACID; POSTSYNAPTIC DENSITY PROTEIN 95; SEPTIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NR1 NMDA RECEPTOR;

ANIMAL CELL; ARTICLE; BRAIN CELL; BRAIN CORTEX; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; IMMUNOBLOTTING; IN VITRO STUDY; NERVE CELL; NEURITE; NONHUMAN; PROTEIN EXPRESSION; RAT; SYNAPSE; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG EFFECT; GENETICS; METABOLISM; POLLUTANT;

ANIMALIA;

ANIMALS; CELL LINE; CEREBRAL CORTEX; ENVIRONMENTAL POLLUTANTS; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES; TETRACHLORODIBENZODIOXIN;

EID: 0037206562     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Apperson, M. L., Moon, I. S., and Kennedy, M. B. (1996) Characterization of densin-180, a new brain-specific synaptic protein of the O-sialoglycoprotein family. J. Neurosci. 16, 6839-6852.
2. Bilder, D., Birnbaum, D., Borg, J. P., Bryant, P., Huigbretse, J., Jansen, E., Kennedy, M. B., Labouesse, M., Legouis, R., Mechler, B., Perrimon, N., Petit, M., and Sinha, P. (2000) Collective nomenclature for LAP proteins. Nat. Cell Biol. 2, E114.
3. Bliss, T. V. and Collingridge, G. L. (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39.
4. Braunewell, K. H. and Manahan-Vaughan, D. (2001) Long-term depression: a cellular basis for learning? Rev. Neurosci. 12, 121-140.
5. Brewer, G. J., Torricelli, J. R., Evege, E. K., and Price, P. J. (1993) Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J. Neurosci. Res. 35, 567-576.
6. Chandler, L. J., Norwood, D., and Sutton, G. (1999) Chronic ethanol upregulates NMDA and AMPA, but not kainate receptor subunit proteins in rat primary cortical cultures. Alcohol. Clin. Exp. Res. 23, 363-370.
7. Cho, K. O., Hunt, C. A., and Kennedy, M. B. (1992) The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron 9, 929-942.
8. 2+/calmodulin kinase inhibitor KN93. J. Neurochem. 70, 1898-1906.
9. Cudmore, S. B. and Gurd, J. W. (1991) Postnatal age and protein tyrosine phosphorylation at synapses in the developing rat brain. J. Neurochem. 57, 1240-1248.
10. Follesa, P. and Ticku, M. K. (1996) NMDA receptor upregulation: molecular studies in cultured mouse cortical neurons after chronic antagonist exposure. J. Neurosci. 16, 2172-2178.
11. Grossman, S. D. and Wrathall, J. R. (2000) The role of activity blockade on glutamate receptor subunit expression in the spinal cord. Brain Res. 880, 183-186.
12. Hollmann, M. and Heinemann, S. (1994) Cloned glutamate receptors. Annu. Rev. Neurosci. 17, 31-108.
13. Hong, S. J., Grover, C. A., Safe, S. H., Tiffany-Castiglioni, E., and Frye, G. D. (1998) Halogenated aromatic hydrocarbons suppress CA1 field excitatory postsynaptic potentials in rat hippocampal slices. Toxicol. Appl. Phannacol. 148, 7-13.
14. Hsu, K. S. and Huang, C. C. (1997) Characterization of the anoxia-induced long-term synaptic potentiation in area CA1 of the rat hippocampus. Br. J. Pharmacol. 122, 671-681.
15. Kalluri, H. S., Mehta, A. K., and Ticku, M. K. (1998) Upregulation of NMDA receptor subunits in rat brain following chronic ethanol treatment. Brain Res. Mol. 58, 221-224.
16. Kennedy, M. B., Bennett, M. K., Bulleit, R. F., Erondu, N. E., Jennings, V. R., Miller, S. G., Molloy, S. S., Patton, B. L., and Schenker, L. J. (1990) Structure and regulation of type II calcium/calmodulin-dependent protein kinase in central nervous system neurons. Cold Spring Harb. Symp. Quant. Biol. 55, 101-110.
17. Kinoshita, A., Noda, M., and Kinoshita, M. (2000) Differential localization of septins in the mouse brain. J. Comp. Neurol. 428, 223-239.
18. Kornau, H. C., Schenker, L. T., Kennedy, M. B., and Seeburg, P. H. (1995) Domain interaction between NMDA receptor sub-units and the postsynaptic density protein PSD-95. Science 269, 1737-1740.
19. Longtine, M. S., DeMarini, D. J., Valencik, M. L., Al-Awar, O. S., Fares, H., De Virgilio, C., and Pringle, J. R. (1996) The septins: roles in cytokinesis and other processes. Curr. Opin. Cell Biol. 8, 106-119.
20. Longtine, M. S., Fares, H., and Pringle, J. R. (1998) Role of the yeast Gin4p protein kinase in septin assembly and the relationship between septin assembly and septin function. J. Cell Biol. 143, 719-736.
21. MacLusky, N. J., Brown, T. J., Schantz, S., Seo, B. W., and Peterson, R. E. (1998) Hormonal interactions in the effects of halogenated aromatic hydrocarbons on the developing brain. Toxicol. Ind. Health. 14, 185-208.
22. 2+-triggered molecular switch. Cell 44, 861-870.
23. Monyer, H., Burnashev, N., Laurie, D. J., Sakmann, B., and Seeburg, P. H. (1994) Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12, 529-540.
24. Moon, I. S., Apperson, M. L., and Kennedy, M. B. (1994) The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2B. Proc. Natl. Acad. Sci. USA 91, 3954-3958.
25. Moon, I. S., Jin, D. H., and Ko, B. H. (1995) Immunological evidence for the enrichment of N-methyl-D-aspartate receptor subunit 2A in the rat postsynaptic density. Mol. Cells 5, 436-441.
26. Mosmann, T. (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity
27. assays. J. Immunol. Methods 65, 55-63.
28. 2+/calmodulin-dependent protein kinase II via dendritic protein synthesis in hippocampal neurons. J. Neurosci. 19, 7823-7833.
29. Patton, B. L., Molloy, S. S., and Kennedy, M. B. (1993) Autophosphorylation of type II CaM kinase in hippocampal neurons: localization of phospho- and dephosphokinase with complementary phosphorylation site-specific antibodies. Mol. Biol. Cell 4, 159-172.
30. Schantz, S. L. and Bowman, R. E. (1989) Learning in monkeys exposed perinatally to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Neurotoxicol. Teratol. 11, 13-19.
31. Schantz, S. L., Seo, B. W., Moshtaghian, J., Peterson, R. E., and Moore, R. W. (1996) Effects of gestational and lactational exposure to TCDD or coplanar PCBs on spatial learning. Neurotoxicol. Teratol. 18, 305-313.
32. Seegal, R. F. and Shain, W. (1992) Neurotoxicity of polychlorinated biphenyls, the role of ortho-ubstituted congeners in altering neurochemical function; in The Vulnerable Brain and Environmental Risks, Isaacson, R. L. and Jensen, K. F. (eds.), Vol. 2, Toxins in food, pp. 169-195, New York.
33. Seo, B. W., Powers, B. E., Widholm, J. J., and Schantz, S. L. (2000) Radial arm maze performance in rats following gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Neurotoxicol. Teratol. 22, 511-519.
34. Seo, B. W., Sparks, A. J., Medora, K., Amin, S., and Schantz, S. L. (1999) Learning and memory in rats gestationally and lactationally exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Neurotoxicol. Teratol. 21, 231-239.
35. Silva, A. J., Paylor, R., Wehner, J. M., and Tonegawa, S. (1992) Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice. Science 257, 206-211.
36. 2+/calmodulin-dependent protein kinase II and α-actinin. J. Neurosci. 21, 423-433.
37. Young, T. H., Huang, J. H., Hung, S. H., and Hsu, J. P. (2000) The role of cell density in the survival of cultured cerebellar granule neurons. J. Biomed. Mater. Res. 1552, 748-753.