Process control for enhanced L-phenylalanine production using different recombinant Escherichia coli strains

Biotechnology and Bioengineering

Volumn 80, Issue 7, 2002, Pages 746-754

  Gerigk, M ^a,c   Bujnicki, R ^a   Ganpo Nkwenkwa, E ^a   Bongaerts, J ^b   Sprenger, G ^a   Takors, Ralf ^a  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b DSM Deutschland GmbH   (Germany)

^c BAYER AG   (Germany)

Author keywords

Acetate; AroF; E. coil; Glucose control; L Phenylalanine; Tyrosine control

Indexed keywords

AMINO ACIDS; BIOREACTORS; ENZYMES; ESCHERICHIA COLI; FERMENTATION; GLUCOSE; METABOLISM; ONLINE SYSTEMS;

FED-BATCH APPROACH;

AROMATIC COMPOUNDS;

2 DEHYDRO 3 DEOXYPHOSPHOHEPTONATE ALDOLASE; GLUCOSE; PHENYLALANINE; TYROSINE; RECOMBINANT PROTEIN;

ARTICLE; BACTERIAL METABOLISM; BACTERIAL STRAIN; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; FERMENTATION; GENOTYPE; NONHUMAN; WILD TYPE; BIOREACTOR; BIOSYNTHESIS; CELL CULTURE; CLASSIFICATION; COMPARATIVE STUDY; EVALUATION; FEEDBACK SYSTEM; GENETIC RECOMBINATION; GENETICS; HOMEOSTASIS; METABOLISM; PHYSIOLOGY; PILOT STUDY; QUALITY CONTROL; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SPECIES DIFFERENCE;

ESCHERICHIA COLI;

BIOREACTORS; CELLS, CULTURED; ESCHERICHIA COLI; FEEDBACK; GLUCOSE; HOMEOSTASIS; PHENYLALANINE; PILOT PROJECTS; QUALITY CONTROL; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECIES SPECIFICITY; TYROSINE;

EID: 0037203064     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10428     Document Type: Article

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