Synthesis of 5-(carboranylalkylmercapto)-2'-deoxyuridines and 3- (carboranylalkyl)thymidines and their evaluation as substrates for human thymidine kinases 1 and 2

Journal of Medicinal Chemistry

Volumn 42, Issue 17, 1999, Pages 3378-3389

  Lunato, Anthony J ^a   Wang, Jianghai ^b   Woollard, Jeffrey E ^c   Anisuzzaman, Abul K M ^a   Ji, Weihua ^a   Rong, Feng Guang ^a   Ikeda, Seiichiro ^a   Soloway, Albert H ^a   Eriksson, Staffan ^b   Ives, David H ^a   Blue, Thomas E ^c   Tjarks, Werner ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^c Ohio State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYURIDINE DERIVATIVE; NUCLEOSIDE DERIVATIVE; THYMIDINE DERIVATIVE; THYMIDINE KINASE;

ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME BINDING; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; REACTION ANALYSIS; STEREOSPECIFICITY;

BORON COMPOUNDS; DEOXYURIDINE; HUMANS; PHOSPHORYLATION; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THYMIDINE; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

EID: 13044283431     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990125i     Document Type: Article

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