Apoptosis signal-regulating kinase/nuclear factor-κB: A novel signaling pathway regulates cardiomyocyte hypertrophy

Circulation

Volumn 105, Issue 4, 2002, Pages 402-404

  Force, Thomas ^a,b   Haq, Syed ^a   Kilter, Heiko ^a   Michael, Ashour ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

Angiotensin; Editorials; Heart failure; Oxidant stress; Signal transduction

Indexed keywords

ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ANGIOTENSIN; APOPTOSIS SIGNAL REGULATING KINASE; CALCINEURIN; ENDOTHELIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; MEMBRANE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE C; THIOREDOXIN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE;

APOPTOSIS; CELL DEATH; DEPHOSPHORYLATION; DNA BINDING; DNA SEQUENCE; EDITORIAL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HEART HYPERTROPHY; HEART INFARCTION; HEART MUSCLE CELL; MECHANICAL STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; VASCULAR SMOOTH MUSCLE;

EID: 0037192315     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/circ.105.4.402     Document Type: Editorial

References (20)

1. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro
2. Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy
3. Cytoplasmic signaling pathways that regulate cardiac hypertrophy
4. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
5. Involvement of nuclear factor-κB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy
6. Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α and angiotensin II
7. Angiotensin II induces gene transcription through cell-type-dependent effects on the nuclear factor-κB transcription factor
8. Mechanical strain activates BNP gene transcription through a p38/NF-κB-dependent mechanism
9. Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes
10. Induction of apoptosis by ASKI, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
11. ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
12. A kinase-independent function of Ask1 in caspase-independent cell death
13. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
14. The transcription factor NF-κB and human disease
15. Regulation of Ets function by protein-protein interactions
16. Glycogen synthase kinase-3β is a negative regulator of cardiomyocyte hypertrophy
17. Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-κB through IκB kinase-α and IκB kinase-β
18. IκB-independent control of NF-κB activity by modulatory phosphorylations
19. Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy
20. 2-terminal kinases