Scale-up of dialysis fermentation for high cell density cultivation of Escherichia coli

Journal of Biotechnology

Volumn 93, Issue 3, 2002, Pages 243-251

  Fuchs, C ^a   Koster D ^a   Wiebusch, S ^a   Mahr, K ^b   Eisbrenner, G ^b   Markl H ^a  

^a HAMBURG UNIVERSITY OF TECHNOLOGY   (Germany)

^b SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

Escherichia coli; External dialysis modules; High cell density cultivation; Protein expression

Indexed keywords

BIOLOGICAL MEMBRANES; DIALYSIS; FERMENTATION; METABOLITES; PROTEINS;

FED BATCH FERMENTATION;

ESCHERICHIA COLI;

OXYGEN;

ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BACTERIUM CULTURE; CELL DENSITY; CELL GROWTH; CELL SUSPENSION; CONTROLLED STUDY; DIALYSIS; FERMENTATION; LABORATORY; MEMBRANE REACTOR; NONHUMAN; OXYGEN SUPPLY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CULTURE MEDIA; DIALYSIS; ESCHERICHIA COLI; FERMENTATION;

ESCHERICHIA COLI;

EID: 0037186266     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1656(01)00402-3     Document Type: Article

References (27)

1. Quorum sensing auto-inducers: Do they play a role in natural microbial habitats?
2. Determination of the kinetic parameters during continuous cultivation of the lipase-producing Thermophile bacillus sp. IHI-91 on olive oil
3. Membrane and bioreactors: A technical challenge in biotechnology
4. The membrane dialysis bioreactor with integrated radial-flow fixed bed - A new approach for continuous cultivation of animal cells
5. Application of an extended Kalman filter method for monitoring high density cultivation of Escherichia coli
6. Acetic acid formation in Escherichia coli fermentation
7. Studies related to the scale-up of high-cell-density E. coli fed-batch fermentations using multiparameter flow cytometry: Effect of a changing microenvironment with respect to glucose and dissolved oxygen concentration
8. High volumetric yields of functional dimeric miniantibodies in Escherichia coli, using an optimised expression vector and high cell density fermentation under non-limited growth conditions
9. Acetate metabolism by Escherichia coli in high cell density fermentation
10. Simple fed-batch technique for high cell density cultivation of Escherichia coli
11. Fermentation of extremophilic microorganisms
12. Dialysis bioreactor with radial-flow fixed bed for animal cell culture
13. Lipase production of Staphylococcus carnosus in a dialysis fermentor
14. High cell density culture of a recombinant Escherichia coli producing penicillin acylase in a membrane cell recycle fermentor
15. Recombinant protein expression in high cell density fed-batch cultures of Escherichia coli
16. Folien und membranen als neue elemente im fermenterbau
17. A new dialysis fermenter for the production of high concentrations of extracellular enzymes
18. Cultivation of E. coli to high cell densities in a dialysis reactor
19. Influence of acetic acid on the growth of Escherichia coli K12 during high-cell-density cultivation in a dialysis reactor
20. Nutrient-split feeding strategy for dialysis cultivation of E. coli
21. Dialysis cultures
22. Membrane dialysis bioreactor with integrated radial-flow fixed bed - A new concept for continuous cultivation of animal cells
23. High-cell-density cultivation of microorganisms
24. Effect of gassing, agitation, substrate supplementation and dialysis on the growth of an extremely thermophilic archaeon Pyrococcus woesei
25. A microfiltration bioreactor to achieve high cell density in Sulfolobus solfataricus fermentation
26. Quorum sensing: Bacterial cell-cell signalling from bioluminescence to pathogenicity