Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity

Cell

Volumn 111, Issue 7, 2002, Pages 1015-1025

  Shin, Byung Sik ^a   Maag, David ^b   Roll Mecak, Antonina ^c   Arefin, M Shamsul ^a   Burley, Stephen K ^c,d   Lorsch, Jon R ^b   Dever, Thomas E ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; INITIATION FACTOR; INITIATION FACTOR EIF5B; INITIATION FACTOR IF2; METHIONINE TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVITY; HYDROLYSIS; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; REGULATORY MECHANISM; RIBOSOME; RNA BINDING; RNA STABILITY; TRANSLATION INITIATION;

EID: 0037184985     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)01171-6     Document Type: Article

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