Inhibition of recombinant KATP channels by the antidiabetic agents midaglizole, LY397364 and LY389382

European Journal of Pharmacology

Volumn 452, Issue 1, 2002, Pages 11-19

  Proks, Peter ^a   Treinies, Iris ^b   Mest, Hans Jürgen ^b   Trapp, Stefan ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b LILLY DEUTSCHLAND GMBH   (Germany)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Diabetes; Imidazoline; Insulin secretion; KATP channel; Kir6.2; Midaglizole

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIDIABETIC AGENT; LY 389382; LY 397364; MIDAGLIZOLE; POTASSIUM CHANNEL; PROTEIN; PROTEIN KIR6 2; RECEPTOR SUBUNIT; SULFONYLUREA RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; IC 50; INSULIN RELEASE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; XENOPUS LAEVIS;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; ELECTROPHYSIOLOGY; GLUCOSE; HYPOGLYCEMIC AGENTS; IMIDAZOLES; INSULIN; MICE; NAPHTHALENES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECOMBINANT PROTEINS;

EID: 0037183714     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02234-3     Document Type: Article

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