|
Volumn 41, Issue 8, 2002, Pages 2712-2718
|
Cytochrome P450 3A4-mediated oxidative conversion of a cyano to an amide group in the metabolism of pinacidil
|
Author keywords
[No Author keywords available]
|
Indexed keywords
HYDROLYTIC PROCESS;
ANTIBODIES;
ENZYME INHIBITION;
HYDROGEN PEROXIDE;
METABOLISM;
NITROGEN OXIDES;
OXIDATION;
REDOX REACTIONS;
BIOCHEMISTRY;
AMIDE;
CYTOCHROME P450;
CYTOCHROME P450 3A4;
CYTOCHROME P450 REDUCTASE;
FERRIC ION;
NITRIC OXIDE SYNTHASE;
NITRILE;
PINACIDIL;
ANIMAL CELL;
ARTICLE;
CATALYST;
CHEMICAL BOND;
CONTROLLED STUDY;
DRUG METABOLISM;
DRUG STRUCTURE;
HUMAN;
HYDROLYSIS;
INSECT;
LIVER MICROSOME;
NONHUMAN;
OXIDATION REDUCTION REACTION;
PRIORITY JOURNAL;
PROTON TRANSPORT;
RAT;
REACTION ANALYSIS;
AMIDES;
CATALYSIS;
CYTOCHROME P-450 ENZYME SYSTEM;
HUMANS;
KINETICS;
MICROSOMES, LIVER;
MIXED FUNCTION OXYGENASES;
NITRILES;
OXIDATION-REDUCTION;
PINACIDIL;
ANIMALIA;
INSECTA;
|
EID: 0037176874
PISSN: 00062960
EISSN: None
Source Type: Journal
DOI: 10.1021/bi0119971 Document Type: Article |
Times cited : (30)
|
References (28)
|