The stereoenantiomers of a pinacidil analog open or close cloned ATP-sensitive K+ channels

Journal of Biological Chemistry

Volumn 277, Issue 43, 2002, Pages 40196-40205

  Lange, Ulf ^a,b   Löffler Walz, Cornelia ^a,b   Englert, Heinrich C ^a,b   Hambrock, Annette ^a,b   Russ, Ulrich ^a,b   Quast, Ulrich ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; HYDROLYSIS;

ENANTIOMERS;

BIOCHEMISTRY;

2 CYANO 1 (1,1 DIMETHYLPROPYL) 3 (3 PYRIDYL)GUANIDINE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE MAGNESIUM; DICYANODIAMIDE DERIVATIVE; GLIBENCLAMIDE; GUANIDINE DERIVATIVE; PINACIDIL; PNU 94750; PNU 96179; PNU 96293; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; SULFONYLUREA RECEPTOR; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; ENANTIOMER; HUMAN; HUMAN CELL; HYDROLYSIS; ISOTOPE LABELING; LIGAND BINDING; MEMBRANE BINDING; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RACEMIC MIXTURE; RECEPTOR BINDING; STEREOCHEMISTRY; STEREOSPECIFICITY; VASODILATATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL LINE; HUMANS; ION CHANNEL GATING; MICE; PATCH-CLAMP TECHNIQUES; PINACIDIL; POTASSIUM CHANNELS; RADIOLIGAND ASSAY; STEREOISOMERISM;

EID: 0037174803     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206685200     Document Type: Article

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