Dopamine treatment of postischemic contractile dysfunction rapidly induces calcium-dependent pro-apoptotic signaling

Circulation

Volumn 106, Issue 13 SUPPL., 2002, Pages

  Stamm, Christof ^a   Friehs, Ingeborg ^a   Cowan, Douglas B ^a   Cao Danh, Hung ^a   Choi, Yeong Hoon ^a   Duebener, Lennart F ^a   McGowan, Francis X ^a   Del Nido, Pedro J ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Apoptosis; Calcium; Inotropic agents; Ischemia

Indexed keywords

ADENOSINE TRIPHOSPHATASE (MAGNESIUM); CALCIUM ION; CALCIUM SENSITIZER; CASPASE 3; CASPASE 8; CASPASE 9; CREATINE KINASE; DIACETYL OXIME; DOPAMINE; ENZYME INHIBITOR; N HYDROXY 5,6 DIMETHOXY 2 BENZO[B]THIOPHENECARBOXIMIDAMIDE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BAX; PROTEIN BCL 2; TRIPHENYLTETRAZOLIUM;

ADRENERGIC STIMULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DISEASE MARKER; DOPAMINE RELEASE; EFFECTOR CELL; ENZYME ACTIVATION; HEART CONTRACTION; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE NECROSIS; HEART MUSCLE REPERFUSION; IMMUNOBLOTTING; MITOCHONDRIAL RESPIRATION; NICK END LABELING; NONHUMAN; PATHOPHYSIOLOGY; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; PROCESS MONITORING; PROTEIN CONTENT; PROTEIN EXPRESSION; RABBIT; SIGNAL TRANSDUCTION; SPECTROFLUOROMETRY;

ANIMALS; APOPTOSIS; CA(2+) MG(2+)-ATPASE; CALCIUM; CARDIOTONIC AGENTS; DIACETYL; DOPAMINE; ENZYME INHIBITORS; HEART; KINETICS; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NECROSIS; ORGANIC CHEMICALS; RABBITS; SIGNAL TRANSDUCTION; VENTRICULAR PRESSURE;

EID: 0037167704     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Meldrum DR, Cleveland JC Jr, Sheridan BC, et al. Cardiac surgical implications of calcium dyshomeostasis in the heart. Ann Thorac Surg. 1996;61:1273-1280.
2. Kroemer G, Dallaporta B, Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol. 1998;60:619-642.
3. Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem J. 1999;341:233-249.
4. del Nido PJ, Glynn P, Buenaventura P, et al. Fluorescence measurement of calcium transients in perfused rabbit heart using rhod-2. Am J Physiol. 1998;274:H728-H741.
5. Stamm C, Friehs I, Cowan DB, et al. Post-ischemic PKC inhibition impairs myocardial calcium handling and increases contractile protein calcium sensitivity. Cardiovasc Res. 2001;51:108-121.
6. Gwathmey JK, Hajjar RJ, Solaro RJ. Contractile deactivation and uncoupling of crossbridges: effects of 2, 3-butanedione monoxime on mammalian myocardium. Circ Res. 1991;69:1280-1292.
7. Grandis DJ, MacGowan GA, Koretsky AP. Comparison of the effects of ORG 30029, dobutamine and high perfusate calcium on function and metabolism in rat heart. J Mol Cell Cardiol. 1998;30:2605-2612.
8. Fliss H, Gattinger D. Apoptosis in ischemic and reperfused rat myocardium. Circ Res. 1996;79:949-956.
9. Kurrelmeyer KM, Michael LH, Baumgarten G, et al. Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. Proc Natl Acad Sci USA. 2000;97:5456-5461.
10. Gottlieb RA, Burlesone KO, Kloner RA, et al. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest. 1994;94:1621-1628.
11. Webster KA, Discher DJ, Kaiser S, et al. Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or a pH shift and is independent of p53. J Clin Invest 1999;104:239-252.
12. Communal C, Singh K, Pimentel DR, et al. Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the beta-adrenergic pathway. Circulation. 1998;98:1329-1334.
13. Saito S, Hiroi Y, Zou Y, et al. Beta-adrenergic pathway induces apoptosis through calcineurin activation in cardiac myocytes. J Biol Chem. 2000; 275:34528-34533.
14. Xi H, Shin WS, Suzuki J, et al. Dystrophin disruption might be related to myocardial cell apoptosis caused by isoproterenol. J Cardiovasc Pharmacol. 2000;36:S25-S29.
15. Henaff M, Hatem SN, Mercardier JJ. Low catecholamine concentrations protect adult rat ventricular cardiomyocytes against apoptosis through cAMP-dependent extracellular signal-regulated kinase activation. Mol Pharmacol. 2000;58:1546-1553.
16. Shneyvays V, Jacobson KA, Li AH, et al. Induction of apoptosis in rat cardiomyocytes by A3 adenosine receptor activation and its suppression by isoproterenol. Exp Cell Res. 2000;267:111-126.
17. Iwai-Kanai E, Hasegawa K, Araki M, et al. Alpha- and beta-adrenergic pathways differentially regulate cell type-specific apoptosis in rat cardiac myocytes. Circulation. 1999;100:305-311.
18. Zaugg M, Xu W, Lucchinetti E, et al. Beta-adrenergic receptor subtypes differentially affect apoptosis in rat adult ventricular myocytes. Circulation. 2000;102:344-350.
19. Shizukuda Y, Buttrick PM, Geenen DL, et al. Beta-adrenergic stimulation causes cardiomyocyte apoptosis: influence of tachycardia and hypertrophy. Am J Physiol. 1998;275:H961-H968.
20. Vatner DE, Asai K, Iwase M, et al. Beta-adrenergic receptor-G proteinadenylyl cyclase signal transduction in the failing heart. Am J Cardiol. 1999;83:80H-85H.
21. Romeo F, Li D, Shi M, et al. Carvedilol prevents epinephrine-induced apoptosis in human coronary artery endothelial cells: modulation of Fas/Fas ligand and caspase-3 pathway. Cardiovasc Res. 2000;45: 788-794.
22. Barzilai A, Zilkha-Falb R, Daily D, et al. The molecular mechanism of dopamine-induced apoptosis: identification and characterization of genes that mediate dopamine toxicity. J Neural Transm Suppl. 2000;60:59-76.
23. Fauvel H, Marchetti P, Chopin C, et al. Differential effects of caspase inhibitors on endotoxin-induced myocardial dysfunction and heart apoptosis. Am J Physiol. 2001;280:H1608-1614.