Angiotensinogen genotype affects renal and adrenal responses to angiotensin II in essential hypertension

Circulation

Volumn 105, Issue 16, 2002, Pages 1921-1927

  Hopkins, Paul N ^a   Hunt, Steven C ^a   Jeunemaitre, Xavier ^a   Smith, Barbara ^a   Solorio, Daniel ^a   Fisher, Naomi D L ^a   Hollenberg, Norman K ^a   Williams, Gordon H ^a  

^a Cardiovascular Genetics   (United States)

Author keywords

Angiotensin; Genetics; Hypertension; Kidney; Renin

Indexed keywords

ANGIOTENSIN; ANGIOTENSINOGEN;

ADULT; AGED; ALDOSTERONE BLOOD LEVEL; ARTICLE; BODY MASS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ESSENTIAL HYPERTENSION; FEMALE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENOTYPE; HUMAN; KIDNEY PLASMA FLOW; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

NON-PROGRAMMATIC;

ADOLESCENT; ADRENAL GLANDS; ADULT; AGED; ALDOSTERONE; ANGIOTENSIN II; ANGIOTENSINOGEN; ANTIHYPERTENSIVE AGENTS; FEMALE; GENOTYPE; HUMANS; HYPERTENSION; KIDNEY; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; RENAL PLASMA FLOW;

EID: 0037161380     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000014684.75359.68     Document Type: Article

References (35)

1. Importance of quantitative genetic variations in the etiology of hypertension
2. Effect of angiotensin II antagonist eprosartan on hyperglycemia-induced activation of intrarenal renin-angiotensin system in healthy humans
3. Renal vascular responses to captopril and to candesartan in patients with type 1 diabetes mellitus
4. Aldosterone: A mediator of myocardial necrosis and renal arteriopathy
5. Role of aldosterone in renal vascular injury in stroke-prone hypertensive rats
6. Responses to converting enzyme and renin inhibition: Role of angiotensin II in humans
7. Renal response to captopril reflects state of local renin system in healthy humans
8. Abnormal renal function, sodium-volume homeostasis and renin system behavior in normal-renin essential hypertension: The evolution of the nonmodulator concept
9. Non-modulation as an intermediate phenotype in essential hypertension
10. Abnormal atrial natriuretic peptide and renal responses to saline infusion in nonmodulating essential hypertensive patients
11. Seven lessons from two candidate genes in human essential hypertension: Angiotensinogen and epithelial sodium channel
12. M235T angiotensinogen gene polymorphism and cardiovascular renal risk
13. Age, gender, and non-modulation: A sexual dimorphism in essential hypertension
14. Adrenal response to angiotensin II in black hypertension: Lack of sexual dimorphism
15. The state and responsiveness of the renin-angiotensin-aldosterone system in patients with type II diabetes mellitus
16. Hyperglycemia and angiotensin-mediated control of the renal circulation in healthy humans
17. Blunted renal vascular response to angiotensin II is associated with a common variant of the angiotensinogen gene and obesity
18. Relationship between insulin resistance and nonmodulating hypertension: Linkage of metabolic abnormalities and cardiovascular risk
19. Insulin resistance in hypertensives: Effect of salt sensitivity, renin status and sodium intake
20. Molecular basis of human hypertension: Role of angiotensinogen
21. Interactions among the alpha2-, beta2-, and beta3-adrenergic receptor genes and obesity-related phenotypes in the Quebec Family Study
22. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro
23. Genetic manipulation of the renin-angiotensin system: Targeted expression of the renin-angiotensin system in the kidney
24. Left ventricular mass, carotid wall thickness, and angiotensinogen gene polymorphism in patients with hypertension
25. Angiotensinogen polymorphism M235T, carotid atherosclerosis, and small-vessel disease-related cerebral abnormalities
26. Association of angiotensinogen gene T235 variant with progression of immunoglobin A nephropathy in Caucasian patients
27. Polymorphisms of renin-angiotensin system genes in childhood IgA nephropathy
28. Genetic polymorphisms of the renin-angiotensin-aldosterone system in end-stage renal disease
29. Relationship between polymorphism in the angiotensinogen, angiotensin-converting enzyme or angiotensin II receptor and renal progression in Japanese NIDDM patients
30. Regulation of ANG II-receptor subtype and its gene expression in adrenal gland
31. Coordinate regulation of canine glomeruli and adrenal angiotensin receptors by dietary sodium manipulation
32. Regulation of primate angiotensin II receptors during altered sodium intake
33. Neural mechanisms in human obesity-related hypertension
34. Body fat, resting and exercise blood pressure and the angiotensinogen M235T polymorphism: The HERITAGE family study
35. Defect in the sodium-modulated tissue responsiveness to angiotensin II in essential hypertension