Interactions among the α2-, β2-, and β3-adrenergic receptor genes and obesity-related phenotypes in the Quebec Family Study

Metabolism: Clinical and Experimental

Volumn 49, Issue 8, 2000, Pages 1063-1070

  Ukkola, O ^a   Rankinen, T ^a   Weisnagel, S J ^a   Sun, G ^a   Perusse, L ^a   Chagnon, Y C ^a   Despres, J P ^a   Bouchard, C ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; BETA ADRENERGIC RECEPTOR; ENDODEOXYRIBONUCLEASE AHAIII; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE;

ADULT; ALLELE; ARTICLE; BODY FAT; CANADA; CHOLESTEROL BLOOD LEVEL; FEMALE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MARKER GENE; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TRIACYLGLYCEROL BLOOD LEVEL; ABDOMEN; ADIPOSE TISSUE; BODY MASS; COHORT ANALYSIS; COMPARATIVE STUDY; FAMILY HEALTH; GENETICS; GENOTYPE; HISTOLOGY; HOMOZYGOTE; METABOLISM;

ABDOMEN; ADIPOSE TISSUE; ADULT; ALLELES; BODY MASS INDEX; COHORT STUDIES; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; FAMILY HEALTH; FEMALE; GENOTYPE; HOMOZYGOTE; HUMANS; MALE; OBESITY; PHENOTYPE; POLYMORPHISM, GENETIC; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, ADRENERGIC, BETA-3;

EID: 0034243110     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1053/meta.2000.7708     Document Type: Article

References (32)

1. Current understanding of the etiology of obesity: Genetic and nongenetic factors
2. β3 and atypical β-adrenoceptors
3. Differential recruitment and differential regulation by physiological amines of fat cell β1, β2 and β3-adrenergic receptors expressed in native fat cells and in transfected cell lines
4. Human fat cell alpha-2 adrenoceptors. I. Functional exploration and pharmacological definition with selected alpha-2 agonists and antagonists
5. Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function
6. The different effects of a Gln27Glu β2-adrenoceptor gene polymorphism on obesity in males and females
7. Association of polymorphisms in the β2-adrenergic receptor gene with obesity, hypertriglyceridaemia, and diabetes mellitus
8. Meta-analysis of the association of the Trp64Arg polymorphism in the beta3 adrenergic receptor with body mass index
9. DNA polymorphisms in the α2- and β2-adrenoceptor genes and regional fat distribution in humans: Association and linkage studies
10. Genetic epidemiology, association and sib-pair linkage: Results from the Quebec Family Study
11. The gross composition of the body
12. The volume of the lung determined by helium dilution: Description of the method and comparison with other procedures
13. Plasma triglycerides related decrease in high-density lipoprotein cholesterol and its association with myocardial infarction in heterozygous familial hypercholesterolemia
14. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
15. Sur un dosage rapide du cholesterol lie aux B-lipoproteins du serum
16. Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays
17. Determination of plasma glucose by hexokinase-glucose-6-phosphate dehydrogenase method
18. Plasma glucose, insulin, and glucagon before and after long-term overfeeding in identical twins
19. Assessment of adipose tissue distribution by computed axial tomography in obese women: Association with body density and anthropometric measurements
20. A routine method for the establishment of permanent growing lymphoblastoid cell lines
21. The Trp64Arg mutation of the β3 adrenergic receptor gene has no effect on obesity phenotypes in the Quebec Family Study and Swedish Obese Subjects cohorts
22. Rapid transfer of DNA from agarose gels to nylon membranes
23. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
24. DraI identifies a two allele DNA polymorphism in the human alpha2-adrenergic receptor gene (ADRAR), using a 5.5 kb probe (p ADRAR)
25. A biallelic DNA polymorphism of the human beta-2-adrenergic receptor detected by BanI-Adrbr-2
26. Functional correlates of α(2A)-adrenoceptor gene polymorphism in the HANE study
27. Aminoterminal polymorphisms of the human β2-adrenergic receptor impart distinct agonist-promoted regulatory properties
28. A polymorphism of the human β2-adrenergic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor
29. Heterogenous distribution of beta- and alpha 2-adrenoceptor binding sites in human fat cells from various fat deposits: Functional consequences