A molecular assembly system that renders antigens of choice highly repetitive for induction of protective B cell responses

Vaccine

Volumn 20, Issue 25-26, 2002, Pages 3104-3112

  Jegerlehner, Andrea ^a   Tissot, Alain ^a   Lechner, Franziska ^a   Sebbel, Peter ^a   Erdmann, Iris ^b   Kündig, Thomas ^b   Bächi, Thomas ^c   Storni, Tazio ^a   Jennings, Gary ^a   Pumpens, Paul ^d   Renner, Wolfgang A ^a   Bachmann, Martin F ^a  

^a CYTOS BIOTECHNOLOGY AG   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d UNIVERSITY OF LATVIA   (Latvia)

Author keywords

Molecular assembly system; Protective B cell responses; Virus like particles

Indexed keywords

ANTIGEN; AUTOANTIGEN; CYSTINE; EPITOPE; HEPATITIS B CORE ANTIGEN; LYSINE; BEE VENOM; CROSS LINKING REAGENT; FLAG PEPTIDE; GRA2 PROTEIN, TOXOPLASMA GONDII; HEPATITIS VACCINE; HYBRID PROTEIN; M PROTEIN, INFLUENZA VIRUS; M-PROTEIN, INFLUENZA VIRUS; MATRIX PROTEIN; PARASITE ANTIGEN; PEPTIDE; PEPTIDE FRAGMENT; PHOSPHOLIPASE A; PROTOZOAL PROTEIN; RECOMBINANT VACCINE;

ANTIGEN ANTIBODY REACTION; ARTICLE; B LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN MODIFICATION; PROTEIN STRUCTURE; STEREOSPECIFICITY; VIRUS CAPSID; VIRUS PARTICLE; ANIMAL; BAGG ALBINO MOUSE; CHEMICAL STRUCTURE; DRUG DESIGN; ENZYMOLOGY; FEMALE; GENETICS; HEPATITIS B VIRUS; IMMUNIZATION; IMMUNOLOGY; MACROMOLECULE; MOUSE; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; VACCINATION; VIRUS INCLUSION;

ANIMAL; B-LYMPHOCYTES; BEE VENOMS; CROSS-LINKING REAGENTS; DRUG DESIGN; FEMALE; HEPATITIS B CORE ANTIGENS; HEPATITIS B VIRUS; IMMUNIZATION; IMMUNODOMINANT EPITOPES; INCLUSION BODIES, VIRAL; MACROMOLECULAR SYSTEMS; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PEPTIDES; PHOSPHOLIPASES A; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; RECOMBINANT FUSION PROTEINS; VACCINATION; VACCINES, SYNTHETIC; VIRAL HEPATITIS VACCINES; VIRAL MATRIX PROTEINS; ANIMALS; ANTIGENS, PROTOZOAN; MACROMOLECULAR SUBSTANCES;

EID: 0037135661     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(02)00266-9     Document Type: Article

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