Platelet glycoprotein IIb/IIIa receptor blockade and coronary resistance in unstable angina

Journal of the American College of Cardiology

Volumn 40, Issue 12, 2002, Pages 2102-2109

  Marzilli, Mario ^a,c   Sambuceti, Gianmario ^b   Testa, Roberto ^b   Fedele, Silvio ^b  

^a UNIVERSITY OF SIENA   (Italy)

^b INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^c UNIVERSITY HOSPITAL OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ADENOSINE; DILTIAZEM; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN; NITRATE;

ADULT; AGED; ANGINA PECTORIS; ARTICLE; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; CORONARY VASCULAR RESISTANCE; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEART CATHETERIZATION; HUMAN; MALE; MICROVASCULATURE; PRIORITY JOURNAL; TRANSLUMINAL CORONARY ANGIOPLASTY; TREATMENT OUTCOME; UNSTABLE ANGINA PECTORIS;

ADULT; AGED; ANGINA, UNSTABLE; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ANTIBODIES, MONOCLONAL; BLOOD FLOW VELOCITY; CORONARY CIRCULATION; FEMALE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MALE; MIDDLE AGED; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; STENTS; TREATMENT OUTCOME; VASCULAR RESISTANCE;

EID: 0037132670     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(02)02590-1     Document Type: Article

References (36)

1. Fitzgerald DJ, Roy L, Catella F, et al. Platelet activation in unstable coronary disease. N Engl J Med 1986;315:983-9.
2. Braunwald E, Maseri A, Armstrong PW, et al. Rationale and clinical evidence for the use of GP IIb/IIIa inhibitors in acute coronary syndromes. Eur Heart J 1998;19 Suppl D:D22-30.
3. Topol EJ, Byzova TV, Plow EF. Platelet GP IIb/IIIa blockers. Lancet 1999;353:227-31.
4. Theroux P, Kouz S, Roy L, et al. Platelet membrane receptor glycoprotein IIb/IIIa antagonism in unstable angina: The Canadian Lamifiban study. Circulation 1996;94:899-905.
5. Schulman SP, Golschmidt-Clermont PJ, Topol EJ, et al. Effects of integrelin, a platelet glycoprotein IIb/IIIa receptor antagonist, in unstable angina: A randomized multicenter trial. Circulation 1996;94:2083-9.
6. The CAPTURE Investigators. Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: The CAPTURE study. Lancet 1997;349:1429-35.
7. The EPIC Investigators. Use of monoclonal antibody directed against the platelet glycoprotein receptor in high-risk coronary angioplasty. N Engl J Med 1994;330:956-61.
8. The EPILOG Investigators. Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization. N Engl J Med 1997;336:1689-96.
9. Zhao XQ, Theroux P, Snapinn SM, Sax FL. Intracoronary thrombus and platelet glycoprotein IIb/IIIa receptor blockade with tirofiban in unstable angina or non-Q-wave myocardial infarction. Circulation 1999;100:1609-15.
10. Khan MM, Ellis SG, Aguirre FV, et al. Does intracoronary thrombus influence the outcome of high risk percutaneous transluminal coronary angioplasty? Clinical and angiographic outcomes in a large multicenter trial. J Am Coll Cardiol 1998;31:31-6.
11. Ellis SG, Lincoff AM, Miller D, et al. Reduction in complications of angioplasty with abciximab occurs largely independently of baseline lesion morphology. J Am Coll Cardiol 1998;32:1619-23.
12. Neumann FJ, Blasini R, Schmitt C, et al. Effect of glycoprotein IIb/IIIa receptor blockade on recovery of coronary blood flow and left ventricular function after the placement of coronary-artery stents in acute myocardial infarction. Circulation 1998;98:2695-701.
13. Bech GJ, De Bruyne B, Pijls NH, et al. Fractional flow reserve to determine the appropriateness of angioplasty in moderate coronary stenosis: A randomized trial. Circulation 2001;103:2928-34.
14. Spears JR, Sandor T, Als AV, et al. Computerized image analysis for quantitative measurement of vessel diameter from cineangiograms. Circulation 1983;68:453-61.
15. The Epistent Investigators. Randomised placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-IIb/IIIa blockade. Lancet 1998;352:87-92.
16. Marzilli M, Sambuceti G, Fedele S, L'Abbate A. Coronary micro-circulatory, vasoconstriction during ischemia in patients with unstable angina. J Am Coll Cardiol 2000;35:327-34.
17. Lipscomb K, Gould KL. Mechanism of the effect of coronary artery stenosis on coronary flow in the dog. Am Heart J 1975;89:60-76.
18. Sambuceti G, Marzullo P, Giorgetti A, et al. Global alteration in perfusion response to increasing oxygen consumption in patients with single-vessel coronary artery disease. Circulation 1994;90:1696-705.
19. Wilson RF, Lesser JF, Laxson DD, White CW. Intense microvascular constriction after angioplasty of acute thrombotic arterial lesions. Lancet 1989;1:807-11.
20. Golino P, Piscione F, Willerson JT, et al. Divergent effects of serotonin on coronary-artery dimensions and blood flow in patients with coronary atherosclerosis and control patients. N Engl J Med 1991;324:641-8.
21. Topol EJ, Yadav JS. Recognition of the importance of embolization in atherosclerotic vascular disease. Circulation 2000;101:570-80.
22. Minamino T, Kitakaze M, Asanuma H, et al. Endogenous adenosine inhibits P-selectin-dependent formation of coronary thromboemboli during hypoperfusion in dogs. J Clin Invest 1998;101:1643-53.
23. Neumann FJ, Zohlnhofer D, Fakhoury L, Ott I, Gawaz M, Schomig A. Effect of glycoprotein IIb/IIIa receptor blockade on platelet-leukocyte interaction and surface expression of the leukocyte integrin Mac-1 in acute myocardial infarction. J Am Coll Cardiol 1999;34:1420-6.
24. de Lemos JA, Antman EM, Gibson CM, et al. Abciximab improves both epicardial flow and myocardial reperfusion in ST-elevation myocardial infarction: Observations from the TIMI 14 trial. Circulation 2000;101:239-43.
25. Thompson RD, Wakelin MW, Larbi KY, et al. Divergent effects of platelet-endothelial cell adhesion molecule-1 and beta-3 integrin blockade on leukocyte transmigration in vivo. J Immunol 2000;165:426-34.
26. Furman MI, Kereiakes DJ, Krueger LA, et al. Leukocyte-platelet aggregation, platelet surface P-selectin, and platelet surface glycoprotein IIIa after percutaneous coronary intervention: Effects of dalteparin or unfractionated heparin in combination with abciximab. Am Heart J 2001;142:790-8.
27. Barrabes JA, Garcia-Dorado D, Mirabet M, et al. Lack of effect of glycoprotein IIb/IIIa blockade on myocardial platelet or polymorphonuclear leukocyte accumulation and on infarct size after transient coronary occlusion in pigs. J Am Coll Cardiol 2002;39:157-65.
28. Nakao K, Ohgushi M, Yoshimura M, et al. Hyperventilation as a specific test for diagnosis of coronary artery spasm. Am J Cardiol 1997;80:545-9.
29. Crea F, Davies G, Chierchia S, et al. Different susceptibility to myocardial ischemia provoked by hyperventilation and cold pressure test in exertional and variant angina pectoris. Am J Cardiol 1985;56:18-22.
30. Morales MA, Reisenhofer B, Rovai D, Moscarelli E, Distante A, L'Abbate A. Hyperventilation-echocardiography test for the diagnosis of myocardial ischaemia at rest. Eur Heart J 1993;14:1088-93.
31. Marzilli M, Klassen GA, Marraccini P, et al. Coronary effects of adenosine in conscious man. Eur Heart J 1989;10 Suppl F:78-81.
32. Sambuceti G, Marzilli M, Marraccini P, et al. Coronary vasoconstriction during myocardial ischemia induced by rises in metabolic demand in patients with coronary artery disease. Circulation 1997;95:2652-9.
33. Virdis A, Ghiadoni L, Marzilli M, et al. Adenosine causes the release of active renin and angiotensin II in the coronary circulation of patients with essential hypertension. J Am Coll Cardiol 1999;33:1677-84.
34. Sambuceti G, Marzilli M, Fedele S, Marini C, L'Abbate A. Paradoxical increase in microvascular resistance during tachycardia downstream from a severe stenosis in patients with coronary artery disease: Reversal by angioplasty. Circulation 2001;103:2352-60.
35. Marzilli M, Orsini E, Marraccini P, Testa R. Beneficial effects of intracoronary adenosine as an adjunct to primary angioplasty in acute myocardial infarction. Circulation 2000;101:2154-9.
36. Shryock JC, Snowdy S, Baraldi PG, et al. A2A-adenosine receptor reserve for coronary vasodilatlon. Circulation 1998;98:711-8.