Diesel exhaust particle extracts and associated polycyclic aromatic hydrocarbons inhibit Cox-2-dependent prostaglandin synthesis in murine macrophages and fibroblasts

Journal of Biological Chemistry

Volumn 277, Issue 42, 2002, Pages 39259-39265

  Rudra Ganguly, Nandini ^a,b   Reddy, Srinivasa T ^a   Korge, Paavo ^b   Herschman, Harvey R ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIESEL ENGINES; ENZYMES; EXHAUST GASES; LIPIDS; ORGANIC ACIDS; PARTICLES (PARTICULATE MATTER); POLYCYCLIC AROMATIC HYDROCARBONS;

DIESEL EXHAUST PARTICLES (DEP);

BIOCHEMISTRY;

ANTHRACENE; BETA NAPHTHOFLAVONE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DIESEL FUEL; ENDOTOXIN; PHENANTHRENE; PHENANTHRENEQUINONE; PHOSPHOLIPASE; POLYCYCLIC AROMATIC HYDROCARBON; PROSTAGLANDIN; QUINONE DERIVATIVE; UNCLASSIFIED DRUG;

AIRBORNE PARTICLE; ALLERGIC PNEUMONITIS; ALLERGY; ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; DIESEL ENGINE; DISEASE EXACERBATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PURIFICATION; EXHAUST GAS; EXTRACTION; FIBROBLAST; GENE EXPRESSION REGULATION; IMMUNOMODULATION; INHIBITION KINETICS; LIGAND BINDING; MACROPHAGE; MACROPHAGE ACTIVATION; MITOGENICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS;

3T3 CELLS; AIR POLLUTION; ANIMALS; ANTHRACENES; ARACHIDONIC ACIDS; BETA-NAPHTHOFLAVONE; CELLS, CULTURED; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTOXINS; ENZYME ACTIVATION; FIBROBLASTS; HYDROCARBONS; IMMUNOBLOTTING; ISOENZYMES; LIGANDS; MACROPHAGES; MEMBRANE PROTEINS; MICE; PHENANTHRENES; PHOSPHOLIPASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; VEHICLE EMISSIONS;

ANIMALIA; MURINAE;

EID: 0037131220     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M110215200     Document Type: Article

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