M-FISH analysis shows that complex chromosome aberrations induced by α-particle tracks are cumulative products of localized rearrangements

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 19, 2002, Pages 12167-12172

  Anderson, Rhona M ^a   Stevens, David L ^a   Goodhead, Dudley T ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA RADIATION; ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME ABERRATION; CHROMOSOME REARRANGEMENT; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPAIR; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE; PRIORITY JOURNAL; SIMULATION;

ALPHA PARTICLES; BIOPHYSICS; CHROMOSOME ABERRATIONS; CHROMOSOME PAINTING; DNA REPAIR; GENE REARRANGEMENT; HUMANS; KARYOTYPING; LYMPHOCYTES; MODELS, GENETIC;

EID: 0037125976     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.182426799     Document Type: Article

References (38)

1. Anderson, R. M., Marsden, S. J., Wright, E. G., Kadhim, M. A., Goodhead, D. T. & Griffin, C. S. (2000) Int. J. Radial. Biol. 76, 31-42.
2. Deng, W., Morrison, D. P., Gale, K. L. & Lucas, J. N. (2000) Int. J. Radiat. Biol. 76, 1589-1598.
3. Tawn, E. J., Whitehouse, C. A., Holdsworth, D., Morris, S. & Tarone, R. E. (2000) Int. J. Radiat. Biol. 76, 355-365.
4. Whang-Peng, J., Young, R. C., Lee, E. C., Longo, D. L., Schechter, G. P. & DeVita, V. T., Jr. (1988) Blood 71, 403-414.
5. Cornforth, M. N. & Bedford, J. S. (1982) Radiat. Res. 111, 385-405.
6. Natarajan, A. T. & Zwanenburg, T. S. (1982) Mutat. Res. 95, 1-6.
7. Brown, J. M., Evans, J. W. & Kovacs, M. S. (1993) Environ. Mol. Mutagen. 22, 218-224.
8. United Nations Scientific Committee on the Effects of Atomic Radiation (2000) in Sources and Effects of Ionizing Radiation (United Nations, New York), Vol. II, pp. 49-72.
9. Durante, M., Cella, L., Furusawa, Y., George, K., Gialanella, G., Grossi, G., Pugliese, M., Saito, M. & Yang, T. C. (1998) Int. J. Radiat. Biol. 73, 253-262.
10. Goodhead, D. T. (1992) Adv. Radiat. Biol. 16, 7-44.
11. Jenner, T. J., deLara, C. M., O'Neill, P. & Stevens, D. L. (1993) Int. J. Radiat. Biol. 64, 265-273.
12. Goodhead, D. T. (1999) J. Radiat. Res. 40, 1-13.
13. Savage, J. R. & Simpson, P. J. (1994) Mutat. Res. 312, 51-60.
14. Griffin, C. S., Marsden, S. J., Stevens, D. L., Simpson, P. & Savage, J. R. (1995) Int. J. Radiat. Biol. 67, 431-439.
15. George, K., Wu, H., Willingham, V., Furusawa, Y., Kawata, T. & Cucinotta, F. A. (2001) Int. J. Radiat. Biol. 77, 175-183.
16. Grigorova, M., Brand, R., Xiao, Y. & Natarajan, A. T. (1998) Int. J. Radiat. Biol. 74, 297-314.
17. Sabatier, L., Al Achkar, W., Hoffschir, F., Luccioni, C. & Dutrillaux, B. (1987) Mutat. Res. 178, 91-97.
18. Knehr, S., Huber, R., Braselmann, H., Schraube, H. & Bauchinger, M. (1999) Int. J. Radiat. Biol. 75, 407-418.
19. Speicher, M. R., Gwyn Ballard, S. & Ward, D. C. (1996) Nat. Genet. 12, 368-375.
20. Greulich, K. M., Kreja, L., Heinze, B., Rhein, A. P., Weier, H. G., Bruckner, M., Fuchs, P. & Molls, M. (2000) Mutat. Res. 452, 73-81.
21. Simpson, P. J. & Savage, J. R. (1996) Int. J. Radiat. Biol. 69, 429-436.
22. Cornforth, M. N. (2001) Radiat. Res. 155, 643-659.
23. Loucas, B. D. & Cornforth, M. N. (2001) Radiat. Res. 155, 660-671.
24. Simpson, P. J., Papworth, D. G. & Savage, J. R. (1999) Int. J. Radiat. Biol. 75, 11-18.
25. Sachs, R. K., Chen, A. M., Simpson, P. J., Hlatky, L. R., Hahnfeldt, P. & Savage, J. R. (1999) Int. J. Radiat. Biol. 75, 657-672.
26. Goodhead, T. G. (1991) in Genes, Cancer and Radiation Protection, ed. Mendelsohn, M. L. (National Council on Radiation Protection and Measurements, Bethesda), pp. 25-37.
27. Sachs, R. K., Chen, A. M. & Brenner, D. J. (1997) Int. J. Radiat. Biol. 71, 1-19.
28. Rothkamm, K., Kuhne, M., Jeggo, P. A. & Lobrich, M. (2001) Cancer Res. 61, 3886-3893.
29. Dolling, J. A., Boreham, D. R., Brown, D. L., Raaphorst, G. P. & Mitchel, R. E. (1997) Int. J. Radiat. Biol. 72, 303-311.
30. Cremer, C., Munkel, C., Granzow, M., Jauch, A., Dietzel, S., Eils, R., Guan, X. Y., Meltzer, P. S., Trent, J. M., Langowski, J. & Cremer, T. (1996) Mutat. Res. 366, 97-116.
31. Savage, J. R. (1993) Environ. Mol. Mutagen. 22, 234-244.
32. Savage, J. R. (1993) Environ. Mol. Mutagen. 22, 198-207.
33. Savage, J. R. (2000) Science 290, 62-63.
34. Cremer, T. & Cremer, C. (2001) Nat. Rev. Genet. 2, 292-301.
35. Nikiforova, M. N., Stringer, J. R., Blough, R., Medvedovic, M., Fagin, J. A. & Nikiforov, Y. E. (2000) Science 290, 138-141.
36. Ludwikow, G., Xiao, Y., Hoebe, R. A., Franken, N. A., Darroudi, F., Stap, J., Van Oven, C. H., Van Noorden, C. J. & Aten, J. A. (2002) Int. J. Radiat. Biol. 78, 239-247.
37. Chadwick, K. H. & Leenhouts, H. P. (1978) Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 33, 517-529.
38. Savage, J. R. & Papworth, D. G. (1973) Mutat. Res. 19, 139-143.