Nitric oxide increases glucose uptake through a mechanism that is distinct from the insulin and contraction pathways in rat skeletal muscle

Diabetes

Volumn 50, Issue 2, 2001, Pages 241-247

  Higaki, Yasuki ^b   Hirshman, Michael F ^b   Fujii, Nobuharu ^b   Goodyear, Laurie J ^a  

^a JOSLIN DIABETES CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; DEOXYGLUCOSE; DRINKING WATER; GLUCOSE; INSULIN; N(G) METHYLARGININE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM; WORTMANNIN;

ANIMAL TISSUE; ARTICLE; ELECTROSTIMULATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBUNIT; EXTENSOR DIGITORUM LONGUS MUSCLE; GLUCOSE TRANSPORT; ISOLATED ORGAN; MALE; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SOLEUS MUSCLE; TREADMILL EXERCISE;

EID: 0035140193     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.50.2.241     Document Type: Article

References (39)

1. The L-arginine-nitric oxide pathway
2. Nitric oxide in skeletal muscle
3. Nitric oxide release is present from incubated skeletal muscle preparations
4. Acute exercise increases nitric oxide synthase activity in skeletal muscle
5. Exercise-stimulated glucose transport in skeletal muscle is nitric oxide dependent
6. Evidence that nitric oxide increases glucose transport in skeletal muscle
7. Nitric oxide stimulates glucose transport and metabolism in rat skeletal muscle in vitro
8. Nitric oxide stimulates skeletal muscle glucose transport through a calcium/contraction- and phosphatidylinositol-3-kinase-independent pathway
9. Insulin stimulation of glucose uptake in skeletal muscles and adipose tissues in vivo is NO dependent
10. Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans
11. The coupling of glucose metabolism and perfusion in human skeletal muscle: The potential role of endothelium-derived nitric oxide
12. Insulin resistance after hypertension induced by the nitric oxide synthesis inhibitor L-NMMA in rats
13. Central nervous system nitric oxide synthase activity regulates insulin secretion and insulin action
14. Dealing with energy demand: The AMP-activated protein kinase
15. The AMP-activated protein kinase: Fuel gauge of the mammalian cell?
16. AMP-activated protein kinase, a metabolic master switch: Possible roles in type 2 diabetes
17. Malonyl-CoA, fuel sensing, and insulin resistance
18. Evidence for 5′ AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport
19. Metabolic stress and altered glucose transport: Activation of AMP-activated protein kinase as a unifying coupling mechanism
20. Effect of AMPK activation on muscle glucose metabolism in conscious rats
21. Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR
22. The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell?
23. Mammalian AMP-activated protein kinase subfamily
24. Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle
25. AMP-activated protein kinase phosphorylation of endothelial NO synthase
26. A muscle-specific insulin receptor knockout challenges the current concepts of glucose disposal and NIDDM pathogenesis
27. Creatine phosphate
28. Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay
29. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
30. Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin
31. Effects of contractile activity on tyrosine phophoproteins and PI 3-kinase activity in rat skeletal muscle
32. Wortmannin inhibits insulin-stimulated but not contraction-stimulated glucose transport activity in skeletal muscle
33. The effects of wortmannin on rat skeletal muscle: Dissociation of signaling pathways for insulin- and contraction-activated hexose transport
34. Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distract from that of insulin
35. Expression of nitric oxide synthase in skeletal muscle: A novel role for nitric oxide as a modulator of insulin action
36. Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle
37. Contraction-induced changes in acetyl-CoA carboxylase and 5′-AMP-activated kinase in skeletal muscle
38. Exercise induces isoform-specific increase in 5′AMP-activated protein kinase activity in human skeletal muscle
39. Cytokines modulate glucose transport in skeletal muscle by inducing the expression of inducible nitric oxide synthase