The Lurcher mutation of an α-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist

Journal of Biological Chemistry

Volumn 275, Issue 12, 2000, Pages 8475-8479

  Taverna, Franco ^a,b,c   Xiong, Zhi Gang ^a   Brandes, Lidia ^a   Roder, John C ^c   Salter, Michael W ^a,b   MacDonald, John F ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ALANINE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; GLUTAMATE RECEPTOR; GLUTAMIC ACID;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS; XENOPUS;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; AMINO ACID SEQUENCE; ANIMALS; ELECTRIC CONDUCTIVITY; EVOKED POTENTIALS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; ION CHANNELS; KAINIC ACID; MICE; MICE, MUTANT STRAINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POINT MUTATION; RECEPTORS, AMPA; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA;

EID: 0034708631     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.12.8475     Document Type: Article

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