Direct killing of xenograft cells by CD8+ T cells of discordant xenograft recipients

Transplantation

Volumn 74, Issue 11, 2002, Pages 1587-1595

  Tanemura, Masahiro ^a   Chong, Anita S ^b   DiSesa, Verdi J ^a   Galili, Uri ^a  

^a RUSH UNIVERSITY   (United States)

^b RUSH MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1,3 GALACTOSYLTRANSFERASE; ANTIGEN; CD8 ANTIGEN; GALACTOSYLTRANSFERASE; INTERLEUKIN 2; RECOMBINANT INTERLEUKIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ANTIGEN PRESENTING CELL; ARTICLE; CELL DIFFERENTIATION; CELL INFILTRATION; CELL SPECIFICITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DISEASE MODEL; GENETIC DIFFERENCE; INCUBATION TIME; ISOGRAFT; KNOCKOUT MOUSE; LYMPHOCYTE CULTURE; MEMBRANE MODEL; MICROENVIRONMENT; MONKEY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE; SPLEEN CELL; SWINE; T LYMPHOCYTE ACTIVATION; XENOGRAFT;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DEATH; CELL LINE; GALACTOSYLTRANSFERASES; HUMANS; KIDNEY; KIDNEY TRANSPLANTATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE; SWINE; T-LYMPHOCYTES, CYTOTOXIC; TRANSPLANTATION, HETEROLOGOUS;

EID: 0037115321     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200212150-00017     Document Type: Article

References (34)

1. Galili U. Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: A major obstacle for xenotransplantation in humans. Immunol Today 1993; 14: 480.
2. Good AH, Cooper DCK, Malcolm A, et al. Identification of carbohydrate structures which bind human anti-porcine antibodies: Implication for discordant xenografting in man. Transplant Proc 1992; 24: 559.
3. Sandrin M, Vaughan HA, Dabkowski PL, et al. Anti-pig IgM antibodies in human serum react predominantly with Gal α1-3Gal epitopes. Proc Natl Acad Sci USA 1993; 90: 11391.
4. Schapherder AFM, Daha MR, Tebulte MTJW, et al. Antibody-dependent cell-mediated cytotoxicity against porcine endothelium induced by a majority of human sera. Transplantation 1994; 57: 1376.
5. Watier H, Guillaumin J-M, Vallee I, et al. Human NK cell-mediated direct and IgG dependent cytotoxicity against xenogeneic porcine endothelial cells. Transplant Immunol 1996; 4: 293.
6. Tanemura M, Yin D, Chong AS, et al. Differential immune response to α-gal epitopes on xenografts and allografts: Implications for accommodation in xenotransplantation. J Clin Invest 2000; 105: 301.
7. Galili U, Tibell A, Samuelsson B, et al. Increased anti-Gal activity in diabetic patients transplanted with fetal porcine islet cell clusters. Transplantation 1995; 59: 1549.
8. Galili U, LaTemple DC, Walgenbach AW, et al. Porcine and bovine cartilage transplants in cynomolgus monkey: II. Changes in anti-Gal response during chronic rejection. Transplantation 1997; 63: 646.
9. Galili U, Chen ZC, Tanemura M, et al. Induced antibody response in xenograft recipients. Graft 2001; 4: 32.
10. Stone KR, Walgenbach AW, Abrams T, et al. Porcine and bovine cartilage transplants in cynomolgus monkey: I. A model for chronic xenograft rejection. Transplantation 1997; 63: 640.
11. Pierson RN, Winn HJ, Russell PS, et al. Xenogeneic skin graft rejection is especially dependent on CD4+ T cells. J Exp Med 1989; 170: 991.
12. Auchincloss H Jr, Moses R, Conti D, et al. Rejection of transgenic skin expressing a xeno-class I antigen is CD4-dependent and CD8-independent. Transplant Proc 1990; 22: 1059.
13. Friedman T, Shimizu A, Smith RN, et al. Human CD4+ T cells mediate rejection of porcine xenografts. J Immunol 1999; 162: 5256.
14. Thall AD, Maly P, Lowe JB. Oocyte Gal α1, 3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse. J Biol Chem 1995; 270: 21437.
15. Tearle RG, Tange MJ, Zannettino ZL. The α-1, 3-galactosyltransferase knockout mouse: Implications for xenotransplantation. Transplantation 1996; 61: 13.
16. Karasuyama H, Melchers F. Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur J Immunol 1988; 18: 97.
17. Kuzumaki N, Fenyo EM, Klein E, et al. Protective effect of murine sarcoma virus-superinfected mouse tumor cells against outgrowth of corresponding noninfected tumor. Transplantation 1978; 26: 304.
18. Galili U, LaTemple DC, Walgenbach AW, et al. Porcine and bovine cartilage transplants in cynomolgus monkey: II. Changes in anti-Gal response during chronic rejection. Transplantation 1997; 63: 646.
19. LaTemple DC, Galili U. Adult and neonatal anti-Gal response in knockout mice for α-galactosyltransferase. Xenotransplantation 1998; 5: 191.
20. Galili U, Shohet SB, Kobrin E, et al. Man, apes, and Old World monkeys differ from other mammals in the expression of α-galactosyl epitopes on nucleated cells. J Biol Chem 1988; 263: 17755.
21. Gorelik E, Duty L, Anaraki F, et al. Alterations of cell surface carbohydrates and inhibition of metastatic property of murine melanomas by alpha 1,3 galactosyltransferase gene transfection. Cancer Res 1995; 55: 4168.
22. Smyth MJ, Sutton VR, Kershaw MH, et al. Xenospecific cytotoxic T lymphocytes use perforin- and Fas-mediated lytic pathways. Transplantation 1996; 62: 1529.
23. Smyth MJ, Kershaw MH, Darcy PK, et al. Adoptive transfer: The role of perforin in mouse cytotoxic T lymphocyte rejection of human tumor xenografts in vivo. Xenotransplantation 1998; 5: 146.
24. Brooks CG, Holscher M, Urdal D. Natural killer activity in cloned cytotoxic T lymphocytes: Regulation by interleukin 2, interferon, and specific antigen. J Immunol 1985; 135: 1145.
25. Moriyama T, Suzuki G, Nakao I, et al. Induction of anomalous killing activity from antigen-specific CTL clones by adding high doses of human recombinant interleukin 2. Cell Immunol 1988; 111: 482.
26. Stone KR, Ayala G, Goldstein J, et al. Porcine cartilage transplants in cynomolgus monkey: III. Transplantation of alpha-galactosidase treated porcine cartilage. Transplantation 1998; 65: 1577.
27. Shishido S, Naziruddin B, Howard T, et al. Recognition of porcine major histocompatibility complex class I antigens by human CD8+ cytolytic T cell clones. Transplantation 1997; 64: 340.
28. Hartig CV, Haller GW, Sachs DH, et al. Naturally developing memory T cell xenoreactivity to swine antigens in human peripheral blood lymphocytes. J Immunol 2000; 164: 2790.
29. Shortman K, Wilson A. Natural and unnatural killing by cytolytic T lymphocytes. Curr Top Microbiol Immunol 1986; 126: 111.
30. Lin Y, Soares MP, Sato K, et al. Rejection of cardiac xenografts by CD4+ or CD8+ T cells. J Immunol 1999; 162: 1206.
31. Grimm EA, Ramsey KM, Mazumder A, et al. Lymphokine-activated killer cell phenomenon: II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells. J Exp Med 1983; 157: 884.
32. Muul LM, Spiess PJ, Director EP, et al. Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma. J Immunol 1987; 138: 989.
33. Rosenberg SA, Packard BS, Aebersold PM, et al. Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma: A preliminary report. N Engl J Med 1988; 319: 1676.
34. Hammond KJ, Pelikan SB, Crowe NY, et al. NKT cells are phenotypically and functionally diverse. Eur J Immunol 1999; 29: 3768.