Assessment of the potential genotoxic risk of Phyllantus orbicularis HBK aqueous extract using in vitro and in vivo assays

Toxicology Letters

Volumn 136, Issue 2, 2002, Pages 87-96

  Sánchez Lamar, Angel ^a   Fuentes, Jorge Luís ^b   Fonseca, Gladys ^a   Cápiro, Nancy ^a   Ferrer, Mirle ^c   Alonzo, Alena ^b   Baluja, Ligia ^a   Cozzi, Renata ^d   De Salvia, Rosella ^e   Fiore, Mario ^e   Llagostera, Montserrat ^c  

^a Universidad De La Habana   (Cuba)

^b CENTRO DE APLICACIONES TECNOLÓGICAS Y DESARROLLO NUCLEAR CEADEN   (Cuba)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^d ROMA TRE UNIVERSITY   (Italy)

^e CRN   (Italy)

Author keywords

Genotoxicity; In vitro and in vivo assays; Phyllanthus orbicularis

Indexed keywords

DNA; PHYLLANTUS ORBICULARIS EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANAPHASE; ANIMAL CELL; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; ASSAY; CHO CELL; CHROMOSOME ABERRATION; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG ACTIVITY; GENE; GENE CONVERSION; GENE MUTATION; GENOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; MICRONUCLEUS; NONHUMAN; PHYLLANTHUS ORBICULARIS; PLANT; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ANAPHASE; ANIMALS; CHO CELLS; CHROMOSOME ABERRATIONS; CRICETINAE; DNA; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DROSOPHILA MELANOGASTER; ESCHERICHIA COLI; FEMALE; MUTAGENICITY TESTS; MUTATION; PHYLLANTHUS; PLANT EXTRACTS; SACCHAROMYCES CEREVISIAE; SALMONELLA TYPHIMURIUM; SOS RESPONSE (GENETICS);

CRICETINAE; CRICETULUS GRISEUS;

EID: 0037114476     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(02)00255-2     Document Type: Article

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