Requirements for developing mixed-chimerism in nonmyeloablative total-lymphoid irradiated mice: Role of IL-4 and immunoredirection

Transplantation

Volumn 74, Issue 7, 2002, Pages 1021-1029

  Field, Elizabeth H ^a,b   Rouse, Todd ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 4 ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHIMERA; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ACTIVATED CELL SORTING; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNE RESPONSE; LYMPH NODE IRRADIATION; LYMPHOCYTOPENIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE;

EID: 0037108894     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200210150-00022     Document Type: Article

References (51)

1. McSweeney PA, Storb R. Mixed chimerism: preclinical studies and clinical applications. Biol Blood Marrow Transplant 1999; 5: 192.
2. Sharabi Y, Sachs DH. Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen. J Exp Med 1989; 169: 493.
3. Sykes M, Szot GL, Swenson KA, et al. Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning. Nat Med 1997; 3: 783.
4. Wekerle T, Kurtz J, Ito H, et al. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment. Nat Med 2000; 6: 464.
5. Slavin S, Fuks Z, Kaplan HS, et al. Transplantation of allogeneic bone marrow without graft-versus-host disease using total lymphoid irradiation. J Exp Med 1978; 147: 963.
6. Vallera DA, Soderling CC, Carlson GJ, et al. Bone marrow transplantation across major histocompatibility barriers in mice. II. T cell requirement for engraftment in total lymphoid irradiation-conditioned recipients. Transplantation 1982; 33: 243.
7. Slavin S, Gottlieb M, Strober S, et al. Transplantation of bone marrow in outbred dogs without graft-versus-host disease using total lymphoid irradiation. Transplantation 1979; 27: 139.
8. Myburgh JA, Smit JA, Browde S. Transplantation tolerance in the primate following total lymphoid irradiation (TLI) and bone marrow (BM) injection. Transplant Proc 1981; 13: 434.
9. Slavin S, Reitz B, Bieber CP, et al. Transplantation tolerance in adult rats using total lymphoid irradiation: permanent survival of skin, heart, and marrow allografts. J Exp Med 1978; 147: 700.
10. Gottlieb M, Strober S, Kaplan HS. Allogeneic marrow transplantation after total lymphoid irradiation (TLI): effect of dose/fraction, thymic irradiation, delayed marrow infusion, and presensitization. J Immunol 1979; 123: 379.
11. Waer M, Ang KK, Van der Schueren E, et al. Influence of radiation field and fractionation schedule of total lymphoid irradiation (TLI) on the induction of suppressor cells and stable chimerism after bone marrow transplantation in mice. J Immunol 1984; 132: 985.
12. Field EH, Steinmuller D. Nondeletional mechanisms of tolerance in totallymphoid irradiation-induced bone marrow chimeras. Transplantation 1993; 56: 250.
13. Field EH, Rouse TM, Gao Q, et al. Association between enhanced Th2/Th1 cytokine profile and donor T-cell chimerism following total lymphoid irradiation. Hum Immunol 1997; 52: 144.
14. Seder RA, Paul WE, Davis MM, et al. The presence ofinterleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice. J Exp Med 1992; 176: 1091.
15. Kopf M, Le Gros G, Bachmann M, et al. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 1993; 362: 245.
16. Heinzel FP, Schoenhaut DS, Rerko RM, et al. Recombinant interleukin 12 cures mice infected with Leishmania major. J Exp Med 1993; 177: 1505.
17. Scott P. IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J Immunol 1991; 147: 3149.
18. Pernis A, Gupta S, Gollob KJ, et al. Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells [comments]. Science 1995; 269: 245.
19. Hsieh CS, Macatonia SE, Tripp CS, et al. Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages [comments]. Science 1993; 260: 547.
20. Croft M, Carter L, Swain SL, et al. Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles. J Exp Med 1994; 180: 1715.
21. Field EH, Becker GC. The immunosuppressive mechanism of total lymphoid irradiation. I. The effect on IL-2 production and IL-2 receptor expression. Transplantation 1989; 48: 499.
22. Field EH, Rouse TM. Alloantigen priming after total lymphoid irradiation alters alloimmune cytokine responses. Transplantation 1995; 60: 695.
23. Taguchi T, McGhee JR, Coffman RL, et al. Detection of individual mouse splenic T cells producing IFN-gamma and IL-5 using the enzyme-linked immunospot (ELISPOT) assay. J Immunol Methods 1990; 128: 65.
24. Field EH, Ye ZX, Rouse TM. Mechanisms of tolerance induction: splenocytes from total lymphoid irradiated mice inhibit the IL-2 pathway in TCR-activated CD4 cells. J Immunol 1996; 157: 3796.
25. Strober S. Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: exploring obscure relationships. Annu Rev Immunol 1984; 2: 219.
26. Strober S, Palathumpat V, Schwadron R, et al. Cloned natural suppressor cells prevent lethal graft-vs-host disease. J Immunol 1987; 138: 699.
27. Strober S, Dejbachsh-Jones S, Van Vlasselaer P, et al. Cloned natural suppressor cell lines express the CD3+CD4-CD8- surface phenotype and the alpha, beta heterodimer of the T cell antigen receptor. J Immunol 1989; 143: 1118.
28. Hayamizu K, Lan F, Huie P, et al. Comparison of chimeric acid and non-chimeric tolerance using posttransplant total lymphoid irradiation: cytokine expression and chronic rejection. Transplantation 1999; 68: 1036.
29. Lan F, Hayamizu K, Strober S. Cyclosporine facilitates chimeric and inhibits nonchimeric tolerance after posttransplant total lymphoid irradiation. Transplantation 2000; 69: 649.
30. Hayashi H, Toki J, Zhexiong L, et al. Long-term (>1 year) analyses of chimerism and tolerance in mixed allogeneic chimeric mice using normal mouse combinations. Stem Cells 2000; 18: 273.
31. Vries-van der Zwan A, van der Pol MA, Besseling AC, et al. Haematopoietic stem cells can induce specific skin graft acceptance across full MHC barriers. Bone Marrow Transplant 1998; 22: 91.
32. Donckier V, Wissing M, Bruyns C, et al. Critical role of interleukin 4 in the induction of neonatal transplantation tolerance. Transplantation 1995; 59: 1571.
33. Gao Q, Chen N, Rouse TM, et al. The role of interleukin-4 in the induction phase of allogeneic neonatal tolerance. Transplantation 1996; 62: 1847.
34. Punch JD, Tono T, Qin L, et al. Tolerance induction by anti-CD2 plus anti-CD3 monoclonal antibodies: evidence for an IL-4 requirement. J Immunol 1998; 161: 1156.
35. Scully R, Cobbold SP, Mellor AL, et al. A role for Th2 cytokines in the suppression of CD8+ T cell-mediated graft rejection. Eur J Immunol 1997; 27: 1663.
36. Cobbold SP, Adams E, Marshall SE, et al. Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CD8. Immunol Rev 1996; 149: 5.
37. Davies JD, Martin G, Phillips J, et al. T cell regulation in adult transplantation tolerance. J Immunol 1996; 157: 529.
38. Bushell A, Morris PJ, Wood KJ. Transplantation tolerance induced by antigen pretreatment and depleting anti-CD4 antibody depends on CD4+ T cell regulation during the induction phase of the response. Eur J Immunol 1995; 25: 2643.
39. Bushell A, Niimi M, Morris PJ, et al. Evidence for immune regulation in the induction of transplantation tolerance: a conditional but limited role for IL-4. J Immunol 1999; 162: 1359.
40. Seder RA, Marth T, Sieve MC, et al. Factors involved in the differentiation of TGF-beta-producing cells from naive CD4+ T cells: IL-4 and IFN-gamma have opposing effects, while TGF-beta positively regulates its own production. J Immunol 1998; 160: 5719.
41. Inobe J, Slavin AJ, Komagata Y, et al. IL-4 is a differentiation factor for transforming growth factor-beta secreting Th3 cells and oral administration of IL-4 enhances oral tolerance in experimental allergic encephalomyelitis. Eur J Immunol 1998; 28: 2780.
42. Gao Q, Rouse TM, Kazmerzak K, et al. CD4+CD25+ cells regulate CD8 cell anergy in neonatal tolerant mice. Transplantation 1999; 68: 1891.
43. Field EH, Matesic D, Rigby S, et al. CD4+CD25+ regulatory cells in acquired MHC tolerance. Immunol Rev 2001; 182: 99.
44. Emoto M, Emoto Y, Kaufmann SH. IL-4 producing CD4+ TCR alpha beta into liver lymphocytes: influence of thymus, beta 2-microglobulin and NK1.1 expression. Int Immunol 1995; 7: 1729.
45. Yoshimoto T, Paul WE. CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J Exp Med 1994; 179: 1285.
46. Arase H, Arase N, Nakagawa K, et al. NK1.1+ CD4+ CD8- thymocytes with specific lymphokine secretion. Eur J Immunol 1993; 23: 307.
47. Bendelac A, Schwartz RH. CD4+ and CD8+ T cells acquire specific lymphokine secretion potentials during thymic maturation. Nature 1991; 353: 68.
48. Bendelac A, Killeen N, Littman DR, et al. A subset of CD4+ thymocytes selected by MHC class I molecules. Science 1994; 263: 1774.
49. Lantz O, Bendelac A. An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans. J Exp Med 1994; 180: 1097.
50. Kimura M, Watanabe H, Ohtsuka K, et al. Radioresistance of intermediate TCR cells and their localization in the body of mice revealed by irradiation. Microbiol Immunol 1993; 37: 641.
51. Lan F, Zeng D, Higuchi M, et al. Predominance of NK1.1+TCR alpha beta+ or DX5+TCR alpha beta+ T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus-host disease: "natural suppressor" cells. J Immunol 2001; 167: 2087.