Regulation of sex-specific differentiation and mating behavior in C. elegans by a new member of the DM domain transcription factor family

Genes and Development

Volumn 16, Issue 18, 2002, Pages 2390-2402

  Lints, Robyn ^a   Emmons, Scott W ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Behavior; C. elegans; DM domain; Dopamine; mab 23; Neuron

Indexed keywords

NEUROTRANSMITTER; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL TISSUE; ARTICLE; BACTERIAL MUTATION; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; GENE EXPRESSION; GENETIC CODE; HUMAN; HYPOTHESIS; MALE; MATING; MORPHOGENESIS; MUSCLE DEVELOPMENT; NERVE CELL; NERVOUS SYSTEM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGENY; PROTEIN DOMAIN; REGULATORY MECHANISM; SENSORY NERVE CELL; SEX DIFFERENTIATION; SUBCUTANEOUS TISSUE;

AMINO ACID SEQUENCE; ANIMALS; BODY PATTERNING; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DROSOPHILA; EVOLUTION; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HELMINTH; GENITALIA, MALE; MALE; MOLECULAR SEQUENCE DATA; MUTATION; NERVOUS SYSTEM; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SEX DIFFERENTIATION; SEXUAL BEHAVIOR, ANIMAL; TRANSCRIPTION FACTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); CAENORHABDITIS; CAENORHABDITIS ELEGANS; HYPODERRIS;

EID: 0037106189     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1012602     Document Type: Article

References (54)

1. A regulatory cascade of three homeobox genes, ceh-10, ttx-3 and ceh-23, control cell fate specification of a defined interneuron class in C. elegans
2. Sex and the single cell. I. On the action of major loci affecting sex determination in Drosophila melanogaster
3. A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans
4. Sex-specific regulation of yolk protein gene expression in Drosophila
5. The genetics of Caenorhabditis elegans
6. Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides
7. The PAX gene egl-38 mediates developmental patterning in Caenorhabditis elegans
8. Characterization of seven genes affecting Caenorhabditis elegans hindgut development
9. The TRA-lA sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene
10. The Drosophila doublesex proteins share a novel zinc finger related DNA binding domain
11. The Hox gene Abdominal-B antagonizes appendage development in the genital disc of Drosophila
12. PHYLIP - Phylogeny Inference Package (Version 3.2)
13. Patterning of Caenorhabditis elegans posterior structures by the Abdominal-B homolog, egl-5
14. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
15. Turning clustering loops: Sex determination in Caenorhabditis elegans
16. Molecular neurogenetics of sexual differentiation and behaviour
17. pha-1, a selectable marker for gene transfer in C. elegans
18. Sexual dimorphism and sex determination
19. Genetic sex determination mechanisms and evolution
20. Natural variation and copulatory plug formation in Caernorhabiditis elegans
21. Nondisjunction mutants of the nematode Caenorhabditis elegans
22. EGL-38 Pax regulates the ovo-related gene lin-48 during Caenorhabditis elegans organ development
23. The Drosophila sex determination hierarchy modulates wingless and decapentaplegic signaling to deploy dachshund sex-specifically in the genital imaginal disc
24. The sex determination gene doublesex regulates the A/P organizer to direct sex-specific patterns of growth in the Drosophila genital imaginal disc
25. The intronerator: Exploring introns and alternative splicing in C. elegans
26. Genetic control and evolution of sexually dimorphic characters in Drosophila
27. Specificity of TGFβ signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans
28. A generalized Hidden Markov Model for the recognition of human genes in DNA
29. Patterning of dopaminergic neurotransmitter identity among Caenorhabditis elegans ray sensory neurons by a TGFβ family signaling pathway and a Hox gene
30. Sensory regulation of male mating behavior in Caenorhabditis elegans
31. Serotonin-deficient mutants and male mating behavior in the nematode Caenorhabditis elegans
32. Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences
33. A Drosophila doublesex-related gene, terra, is involved in somitogenesis in vertebrates
34. Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination
35. TGFβ-related pathways. Roles in Caenorhabditis elegans development
36. LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway
37. Evidence for evolutionary conservation of sex-determining genes
38. Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation
39. Mutations in the unc-52 gene responsible for body wall muscle defects in adult Caenorhabditis elegans are located in alternatively spliced exons
40. Sex determination genes control the development of the Drosophila genital disc, modulating the response to Hedgehog, Wingless and Decapentaplegic signals
41. Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor β pathway components
42. C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway
43. mab-3, a gene required for sex-specific yolk protein expression and a male-specific lineage in C. elegans
44. Post-embryonic cell lineages of the nematode Caenorhabditis elegans
45. The Caenorhabditis elegans male: Postembryonic development of nongonadal structures
46. A BMP homolog acts as a dose-dependent regulator of body size and male tail patterning in Caenorhabditis elegans
47. A homeotic gene cluster patterns the anteroposterior body axis of C. elegans
48. The anatomy
49. Inhibition of touch cell fate by egl-44 and egl-46 in C. elegans
50. Similarity of DNA binding and transcriptional regulation by Caenorhabditis elegans MAB-3 and Drosophila melanogaster DSX suggests conservation of sex determining mechanisms
51. mab-3 is a direct tra-1 target gene regulating diverse aspects of C. elegans male sexual development and behavior
52. Establishing sexual dimorphism: Conservation amidst diversity?
53. Molecular analysis of the C. elegans sex-determining gene tra-1: A gene encoding two zinc finger proteins
54. Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers