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Volumn 64, Issue 4, 2002, Pages 669-675
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Effects of antifolates on the binding of 5-fluoro-2′-deoxyuridine monophosphate to thymidylate synthase
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Author keywords
ALIMTA; Antifolate; FdUMP binding; Polyglutamylation; Raltitrexed; Thymidylate synthase
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Indexed keywords
2 [5 [[(1,2 DIHYDRO 3 METHYL 1 OXOBENZO[F]QUINAZOLIN 9 YL)METHYL]AMINO] 1 OXO 2 ISOINDOLINYL]GLUTARIC ACID;
AMMONIUM SULFATE;
FLOXURIDINE PHOSPHATE;
FOLIC ACID ANTAGONIST;
FOLIC ACID DERIVATIVE;
GLUTAMIC ACID DERIVATIVE;
LY 247292;
METESIND GLUCURONATE;
MULTITARGETTED ANTIFOLATE;
NOLATREXED;
PENTAGLUTAMATE;
POLYGLUTAMIC ACID;
RALTITREXED;
THYMIDYLATE SYNTHASE;
UNCLASSIFIED DRUG;
ARTICLE;
CHEMICAL REACTION;
CONCENTRATION RESPONSE;
CONFORMATIONAL TRANSITION;
DISSOCIATION CONSTANT;
DRUG BINDING;
DRUG CONFORMATION;
DRUG STABILITY;
ENZYME BINDING;
ENZYME SUBSTRATE;
LACTOBACILLUS CASEI;
LIPOPHILICITY;
PRIORITY JOURNAL;
BINDING, COMPETITIVE;
CELL-FREE SYSTEM;
DRUG INTERACTIONS;
FLUORODEOXYURIDYLATE;
FOLIC ACID ANTAGONISTS;
HUMANS;
KINETICS;
LACTOBACILLUS CASEI;
THYMIDYLATE SYNTHASE;
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EID: 0037103677
PISSN: 00062952
EISSN: None
Source Type: Journal
DOI: 10.1016/S0006-2952(02)01219-4 Document Type: Article |
Times cited : (11)
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References (26)
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