Response of hairy cells to IFN-α involves induction of apoptosis through autocrine TNF-α and protection by adhesion

Blood

Volumn 100, Issue 2, 2002, Pages 647-653

  Baker, Peter K ^a,b   Pettitt, Andrew R ^a   Slupsky, Joseph R ^a   Chen, Hai J ^a   Glenn, Mark A ^a   Zuzel, Mirko ^a   Cawley, John C ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; FIBRONECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN; TUMOR NECROSIS FACTOR ALPHA; VITRONECTIN;

APOPTOSIS; ARTICLE; CANCER CELL; CELL ADHESION; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFECT; DRUG SENSITIVITY; HAIRY CELL LEUKEMIA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SENSITIZATION;

EID: 0037100386     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V100.2.647     Document Type: Article

References (48)

1. Effects of interferon α on autocrine growth factor loops in B lymphoproliferative disorders
2. B-cell growth factor-induced and α-interferon-inhibited proliferation of hairy cells coincides with modulation of cell surface antigens
3. Effects of tumour necrosis factor and α interferon on chronic B cell malignancies
4. Hairy-cell leukaemia
5. Specific tissue invasion, localisation and matrix modification in hairy-cell leukemia
6. The bone marrow fibrosis of hairy-cell leukemia is caused by the synthesis and assembly of a fibronectin matrix by the hairy cells
7. Hairy cell interactions with extracellular matrix: Expression of specific integrin receptors and their role in the cell's response to specific adhesive proteins
8. Interferon is effective in hairy-cell leukaemia
9. Tumour necrosis factor as an autocrine tumour growth factor for chronic B-cell malignancies
10. Novel purification of vitronectin from human plasma by heparin affinity chromatography
11. Reduction in mitochondrial membrane potential constitutes an early irreversible step of programmed lymphocyte death in vivo
12. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
13. Mitochondrial control of apoptosis
14. The study of apoptotic cells by flow cytometry
15. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
16. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
17. Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
18. Antibodies and crossmatching for transplantation
19. Role of poly(ADP-ribosyl)ation in the killing of chronic lymphocytic leukemia cells by purine analogues
20. Integrin signaling
21. Interferon α augments activation-induced T cell death by upregulation of Fas (CD95/APO-1) and Fas ligand expression
22. Azidothymidine and interferon-α induce apoptosis in herpesvirus-associated lymphomas
23. Interferon-α enhances CD95L-induced apoptosis of human malignant glioma cells
24. Differential induction of apoptosis by Fas-Fas ligand interactions in human monocytes and macrophages
25. CD95 (Fas)-induced caspase-mediated proteolysis of NF-κB
26. Recombinant IFN-α (2b) increases the expression of apoptosis receptor CD95 and chemokine receptors CCR1 and CCR3 in monocytoid cells
27. Involvement of Fas-mediated apoptosis in the inhibitory effects of interferon-α in chronic myelogenous leukemia
28. Induction of Fas ligand-mediated apoptosis by interferon-α
29. Age-related changes in interferon-α/β receptor expression, binding, and induction of apoptosis in natural killer cells from C57BL/6 mice
30. IFNα sensitizes ME-180 human cervical cancer cells to TNFα-induced apoptosis by inhibiting cytoprotective NF-κB activation
31. Autocrine loop of tumor necrosis factor induced by interferon-α in tumor cells from hairy cell leukemia
32. Interferon-γ sensitizes human myeloid leukemia cells to death receptor-mediated apoptosis by a pleiotropic mechanism
33. Death receptors: Signalling and modulation
34. Fibronectin binding promotes a PKC-dependent modulation of NF-κ B in human T cells
35. Integrin signaling to NF-kappa B in monocytic leukemia cells is blocked by activated oncogenes
36. NF-κB mediates αvβ3 integrin-induced endothelial cell survival
37. The interferons and cell death: Guardians of the cell or accomplices of apoptosis?
38. Signaling pathways activated by interferons
39. Proliferative response of hairy cells to B cell growth factor (BCGF): In vivo inhibition by interferon-α and in vitro effects of interferon-α, -β, and -γ
40. Modulation of Apo-1/Fas (CD95)-induced programmed cell death in myeloma cells by interferon-α 2
41. Two CD95 (APO-1/Fas) signaling pathways
42. IFN-α in vivo enhances tumor necrosis factor receptor levels on hairy cells
43. Production of tumor necrosis factor-α by normal and malignant B lymphocytes in response to interferon-α, interferon-γ and interleukin-4
44. IFN-α suppresses activation of nuclear transcription factors NF-κB and activator protein 1 and potentiates TNF-induced apoptosis
45. Interferon gamma (IFNγ) and tumor necrosis factor alpha synergism in ME-180 cervical cancer cell apoptosis and necrosis
46. NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation