Genomic organization and restricted expression of the human Mona/Gads gene suggests regulation by two specific promoters

Gene

Volumn 290, Issue 1-2, 2002, Pages 173-179

  Guyot, B ^a   Arnaud, S ^a   Phothirath, P ^b   Bourette, R P ^a   Grasset, M F ^a   Rigal, D ^b   Mouchiroud, G ^a  

^a CENTRE DE GÉNÉTIQUE MOLÉCULAIRE ET CELLULAIRE   (France)

^b Etablissement de Transfus Sanguine   (France)

Author keywords

5 untranslated region; Hematopoiesis; Polyadenylation site; Signalling molecule; Transcriptional regulation

Indexed keywords

PROTEIN; PROTEIN MONOCYTIC ADAPTER; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ARTICLE; BONE MARROW CELL; CELL ASSAY; CELL LINE; CELL TYPE; CONTROLLED STUDY; EXON; GENE CONTROL; GENE EXPRESSION; GENE STRUCTURE; GENETIC TRANSCRIPTION; GENOME ANALYSIS; GENOMIC FRAGMENT; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; POLYADENYLATION; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; REPORTER GENE; SEQUENCE ANALYSIS; T LYMPHOCYTE; THROMBOCYTE;

3' UNTRANSLATED REGIONS; 5' FLANKING REGION; 5' UNTRANSLATED REGIONS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BASE SEQUENCE; CARRIER PROTEINS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENES; HUMANS; JURKAT CELLS; K562 CELLS; LUCIFERASES; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

DOMINGOA HAEMATOCHILA;

EID: 0037094326     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(02)00555-3     Document Type: Article

References (18)

1. Grf40, a novel Grb2 family member, is involved in T cell signalling through interaction with SLP-76 and LAT
2. Interaction of linker for activation of T cells with multiple adapter proteins in platelets activated by the glycoprotein VI-selective ligand, convulxin
3. Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development
4. Expression of Mona (monocytic adaptor) in myeloid progenitor cells results in increased and prolonged MAP kinase activation upon macrophage colony-stimulating factor stimulation
5. Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development
6. Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice
7. Association of Sos Ras-exchange protein with Grb2 is implicated in tyrosine kinase transduction and transformation
8. GRID: A novel Grb-2-related adapter protein that interacts with the activated T-cell costimulatory receptor CD28
9. Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65
10. GrpL, a Grb2-related adaptor protein, interacts with SLP-76 to regulate nuclear factor of activated T cell activation
11. The hematopoietic-specific adaptor protein Gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors
12. The role of Gads in hematopoietic cell signalling
13. Protein-protein interactions define specificity in signal transduction
14. Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76
15. Molecular cloning and expression of human Grap-2, a novel leukocyte- specific SH2- and SH3-containing adaptor-like protein that binds to Gab-1
16. Thrombospondin binds to monocytes-macrophages and mediates platelet-monocyte adhesion
17. Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)
18. Requirement for the SLP-76 adaptor GADS in T cell development