Adenovirus gene therapy for ovarian cancer

Journal of the National Cancer Institute

Volumn 94, Issue 10, 2002, Pages 706-707

  Russell, Willie ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POLY[N (2 HYDROXYPROPYL)METHACRYLAMIDE]; PROTEIN P53; THYMIDINE KINASE; VIRUS RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; CAUSE OF DEATH; CELL DIVISION; COXSACKIE VIRUS; CYTOLYSIS; CYTOTOXICITY; EDITORIAL; EXPERIMENTAL MODEL; GENE TARGETING; GENE THERAPY; HERPES VIRUS; IMMUNE RESPONSE; IN VIVO STUDY; MOUSE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; TRANSGENE; TUMOR CELL; TUMOR IMMUNITY; TUMOR SUPPRESSOR GENE;

EID: 0037094280     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/94.10.706     Document Type: Editorial

References (20)

1. Update on adenovirus and its vectors
2. A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
3. Clinical research results with d11520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: What have we learned?
4. Loss of adenoviral receptor expression in human bladder cancer cells: A potential impact on the efficacy of gene therapy
5. In vivo molecular chemotherapy and noninvasive imaging with an infectivity enhanced virus
6. Treatment of ovarian cancer with a tropism modified oncolytic adenovirus
7. Detection and measurement of in vitro gene transfer by gamma camera imaging
8. Neutralisation of adenovirus infectivity by ascitic fluid from ovarian cancer patients
9. Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies
10. Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer
11. Effect of p53 gene transfer and cisplatin in a peritonitis carcinomatosa model with p53-deficient ovarian cancer cells
12. Inhibition of phosphatidylinositol 3′-kinase increases efficacy of paclitaxel in in vitro and in vivo ovarian cancer models
13. Growth suppression of human ovarian cancer cells by adenovirus-mediated transfer of the PTEN gene
14. Heterogeneity of ovarian cancer: Relationships among histological group, stage of disease, tumor markers, patient characteristics, and survival
15. Selectivity of TAG-72-targeted adenovirus gene transfer to primary ovarian carcinoma cells versus autogolous mesothelial cells in vitro
16. Large nontransplanted hepatocellular carcinoma in woodchucks: Treatment with adenovirus-mediated delivery of interleukin 12/B7.1 genes
17. Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells
18. Adenovirus serotype 30 fiber does not mediate transduction via the coxsackie-adenovirus receptor
19. Replicative adenoviruses for cancer therapy
20. Replication and cytolysis of an E1B-attenuated adenovirus in drug-resistant ovarian tumour cells is associated with reduced apoptosis