Evidence for a localization of [3H]nociceptin binding sites on medullar primary afferent fibers

Journal of Neuroscience Research

Volumn 68, Issue 4, 2002, Pages 496-500

  Le Cudennec, C ^a   Suaudeau, C ^a   Costentin, J ^a  

^a Boulevard Gambetta   (France)

Author keywords

Autoradiography; ORL1 receptor; Rat; Spinal cord deafferentation

Indexed keywords

NOCICEPTIN; OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; CONTROLLED STUDY; DEAFFERENTATION; INTERNEURON; MALE; MEDULLA OBLONGATA; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; RAT; RECEPTOR DENSITY; RHIZOTOMY; SENSORY NERVE CELL; SPINAL CORD; SPINAL CORD DORSAL HORN; SPINAL CORD VENTRAL HORN;

AFFERENT PATHWAYS; ANIMALS; AUTORADIOGRAPHY; CERVICAL VERTEBRAE; INTERNEURONS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID; RHIZOTOMY; SPINAL CORD; SPINAL NERVE ROOTS; TRITIUM;

EID: 0037093774     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10218     Document Type: Article

References (40)

1. Effects of central lesions on disorders produced by multiple dorsal rhizotomy in rats
2. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or κ opioid receptor type
3. Nociceptin, an endogenous ligand for the ORL1 receptor, decreases cardiac output and total peripheral resistance in the rat
4. Contralateral projection of primary afferent fibers to mammalian spinal cord
5. 3H]nociceptin binding sites in the rat brain
6. Nociceptin stimulates locomotion and exploratory behaviour in mice
7. 3H]nociceptin binding sites from telencephalic to mesencephalic regions of the mouse brain
8. cDNA cloning and regional distribution of a novel member of the opioid receptor family
9. Changes in cholinergic and opioid receptors in the rat spinal cord, dorsal root and sciatic nerve after ventral and dorsal root lesion
10. The inhibition effect of nociceptin on micturition reflex in anaesthetized rats
11. Reorganization of the spinal dorsal horn in models of chronic pain, correlation with behaviour
12. Nociceptin, an endogenous agonist for central opioid like 1 (ORZ1) receptors possesses systemic vasorelaxant properties
13. Characterization of nociceptin hyperalgesia and allodynia in conscious mice
14. Orphanin FQ acts as an anxiolytic to behavioral responses to stress
15. Pronociceptive effects of the neuropeptide, nociceptin, in the land snail, Cepea nemoralis
16. Spinal analgesic activity of orphanin FQ/nociceptin and its fragments
17. Deafferentation hypersensitivity in the rat after dorsal rhizotomy, a possible animal model of chronic pain
18. Enhancement of spatial attention in nociceptin/orphanin FQ receptor-knockout mice
19. Nociceptin system plays a role in the memory retention, involvement of naloxone benzoylhydrazone binding sites
20. Isolation and structure of the endogenous agonist of opioid receptor-like OPL1 receptor
21. Inhibition of nociceptin-induced allodynia in conscious mice by prostaglandin D2
22. Orphanin FQ is a functional anti-opioid peptide
23. Cytoarchitectonic organization of the spinal cord in the rat. II. The cervical and upper thoracic cord
24. ORL1, a novel member of the opioid receptor family, cloning, functional expression and localization
25. Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphanin FQ receptor
26. Identification and charaterization of an endogenous ligand for opioid receptor homologue ROR-C, its involvement in allodynic response to innocuous stimulus
27. Peripheral and central actions of orphanin FQ (nociceptin) on murine colon
28. Orphanin FQ, agonist of orphan opioid receptor ORL1, stimulates feeding in rats
29. Orphanin FQ, a neuropeptide that activates an opioid like G protein-coupled receptor
30. Nociceptin receptor activation inhibits tachykinergic non-adrenergic non-cholinergic contractions in the guinea pig isolated bronchus
31. Naloxone sensitive orphanin FQ-induced analgesia in mice
32. Nociceptin inhibits non-adrenergic non-cholinergic contraction in the guinea pig airway
33. Inhibitory action of nociceptin on spinal dorsal horn neurones of the rat, in vivo
34. Changes of opioid binding density in the rat spinal cord following unilateral dorsal rhizotomy
35. Injections of nociceptin into nucleus accumbens shell or ventromedial hypothalamic nucleus increase food intake
36. Nociceptin-induced apparent hyperalgesia in mice as a result of the prevention of opioid autoanalgesic mechanism triggered by the stress of an intracerebroventricular injection
37. Changes in head-dipping behavior in the hole-board test reflect the anxiogenic and/or anxiolytic state in mice
38. Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned μ, δ and κ opioid receptors
39. Nociceptin or antinociceptin, potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat
40. Analgesic effect of intrathecally administered nociceptin, an opioid receptor-like 1 receptor agonist, in the rat formalin test