Peripheral and central actions of orphanin FQ (nociceptin) on murine colon

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 276, Issue 1 39-1, 1999, Pages

  Osinski, M A ^a   Bass, P ^a   Gaumnitz, E A ^a,b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

Author keywords

Central nervous system; Enteric nervous system; Opioid; Transit

Indexed keywords

CHARCOAL; CHLORPROMAZINE; DRUG VEHICLE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; MORPHINE SULFATE; NALTREXONE; NOCICEPTIN; OPIATE ANTAGONIST; OPIATE PEPTIDE; TETRODOTOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLON MOTILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; GASTROINTESTINAL TRANSIT; INTESTINE CONTRACTION; INTESTINE TRANSIT TIME; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; MOUSE; NERVE TRACT; NONHUMAN; PERISTALSIS; PRIORITY JOURNAL; STOMACH EMPTYING;

EID: 0032896360     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.276.1.g125     Document Type: Article

References (40)

1. Anton, B., J. Fein, T. To, X. Li, L. Silberstein, and C. J. Evans. Immunohistochemical localization of ORL-1 in the central nervous system of the rat. J. Comp. Neurol. 368: 229-251, 1996.
2. Bunzow, J. R., C. Saez, M. Mortrud, C. Bouvier, J. T. Williams, M. Low, and D. K. Grandy. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or κ opioid receptor type. FEBS Lett. 347: 284-288, 1994.
3. Chen, Y., A. Mestek, J. Liu, and L. Yu. Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the μ and δ opioid receptors. Biochem. J. 295: 625-628, 1993.
4. Connor, M., C. W. Vaughan, B. Chieng, and M. J. Christie. Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro. Br. J. Pharmacol. 119: 1614-1618, 1996.
5. 2+ in the SH-SY5Y human neuroblastoma cell line. Br. J. Pharmacol. 118: 205-207, 1996.
6. De Luca, A., and I. M. Coupar. Insights into opioid action in the intestinal tract. Pharmacol. Ther. 69: 103-115, 1996.
7. Devine, D. P., L. Taylor, R. K. Reinscheid, F. J. Monsma, O. Civelli, and H. Akil. Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ. Neurochem. Res. 21: 1387-1396, 1996.
8. Evans, C. J., D. E. Keith, Jr., H. Morrison, K. Magendzo, and R. H. Edwards. Cloning of a delta opioid receptor by functional expression. Science 258: 1952-1955, 1992.
9. Fontaine, J., and J. Reuse. Contractor responses of the isolated colon of the mouse to morphine and some opioid peptides. Br. J. Pharmacol. 85: 861-867, 1985.
10. Fukuda, K., S. Kato, K. Mori, M. Nishi, H. Takeshima, N. Iwabe, T. Miyata, T. Houtani, and T. Sugimoto. cDNA cloning and regional distribution of a novel member of the opioid receptor family. FEBS Lett. 343: 42-46, 1994.
11. Hornby, P. J., D. R. Kapusta, and Z. K. Krowicki. Potent gastric motor and cardiovascular responses to intravenously administered nociceptin in the rat (Abstract). Gastroenterology 114: A767, 1998.
12. Jacoby, H. I., and I. Lopez. A method for the evaluation of colonic propulsive motility in the mouse after ICV administered compounds (Abstract). Dig. Dis. Sci. 29: 551, 1984.
13. Kieffer, B. L., K. Befort, C. Gaveriaux-Ruff, and C. G. Hirth. The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proc. Natl. Acad. Sci. USA 89: 12048-12052, 1992.
14. Lachowicz, J. E., Y. Shen, F. J. Monsma, Jr., and D. R. Sibley. Molecular cloning of a novel G protein-coupled receptor related to the opiate receptor family. J. Neurochem. 64: 34-40, 1995.
15. Laursen, S. E., and J. K. Belknap. Intracerebroventricular injections in mice. Some methodological refinements. J. Pharmacol. Methods 16: 355-357, 1986.
16. Lord, J. A., A. A. Waterfield, J. Hughes, and H. W. Kosterlitz. Endogenous opioid peptides: multiple agonists and receptors. Nature 267: 495-499, 1977.
17. Macht, D. I., and J. Barba-Gose. Two new methods for pharmacological comparison of insoluble purgatives. J. Am. Pharm. Assoc. (Wash.) 20: 558-564, 1931.
18. Martin, W. R., C. G. Eades, J. A. Thompson, R. E. Huppler, and P. E. Gilbert. The effects of morphine- and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog. J. Pharmacol. Exp. Ther. 197: 517-532, 1976.
19. Meunier, J. C., C. Mollereau, L. Toll, C. Suaudeau, C. Moisand, P. Alvinerie, J. L. Butour, J. C. Guillemot, P. Ferrara, B. Monsarrat, H. Mazargull, G. Vassart, M. Parmentier, and J. Costentin. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 377: 532-535, 1995.
20. Mogil, J. S., J. E. Grisel, K. K. Reinscheid, O. Civelli, J. K. Belknap, and D. K. Grandy. Orphanin FQ is a functional anti-opioid peptide. Neuroscience 75: 333-337, 1996.
21. Mogil, J. S., J. E. Grisel, G. Zhangs, J. K. Belknap, and D. K. Grandy. Functional antagonism of μ-, δ- and κ-opioid antinociception by orphanin FQ. Neurosci. Lett. 214: 131-134, 1996.
22. Mollereau, C., M. Parmentier, P. Mailleux, J. L. Butour, C. Moisand, P. Chalon, D. Caput, G. Vassart, and J. C. Meunier. ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization. FEBS Lett. 341: 33-38, 1994.
23. Nijkamp, F. P., and J. M. Van Ree. Effects of endorphins on different parts of the gastrointestinal tract of rat and guinea-pig in vitro. Br. J. Pharmacol. 68: 599-606, 1980.
24. Nishi, M., T. Houtani, Y. Noda, T. Mamiya, K. Sato, T. Doi, J. Kuno, H. Takeshima, T. Nukada, T. Nabeshima, T. Yamashita, T. Noda, and T. Sugimoto. Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphanin FQ receptor. EMBO J. 16: 1858-1864, 1997.
25. Osinski, M. A., M. P. Pampusch, M. P. Murtaugh, and D. R. Brown. Expression of nociceptin receptor message in porcine gastrointestinal tract (Abstract). Soc. Neurosci. Abstr. 22: 2003, 1996.
26. Pert, C. B., and S. H. Snyder. Opiate receptor: demonstration in nervous tissue. Science 179: 1011-1014, 1973.
27. Plant, O. H., and G. H. Miller. Effects of morphine and some other opium alkaloids on the muscular activity of the alimentary canal. I. Action on the small intestine in unanesthetized dogs and man. J. Pharmacol. Exp. Ther. 27: 361-383, 1926.
28. Porreca, F., H. I. Mosberg, R. Hurst, V. J. Hruby, and T. F. Burks. Roles of μ, δ and κ opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse. J. Pharmacol. Exp. Ther. 230: 341-348, 1984.
29. Raffa, R. B., J. R. Mathiasen, and H. I. Jacoby. Colonic bead expulsion time in normal and mu-opioid receptor deficient (CXBK) mice following central (ICV) administration of mu- and delta-opioid agonists. Life Sci. 41: 2229-2234, 1987.
30. Reinscheid, R. K., A. Ardati, F. J. Monsma, Jr., and O. Civelli. Structure-activity relationship studies on the novel neuropeptide orphanin FQ. J. Biol. Chem. 271: 14163-14168, 1996.
31. Reinscheid, R. K., H. P. Nothacker, A. Bourson, A. Ardati, R. A. Henningsen, J. R. Bunzow, D. K. Grandy, H. Langen, F. J. Monsma, Jr., and O. Civelli. Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science 270: 792-794, 1995.
32. Rossi, G. C., L. Leventhal, and G. W. Pasternak. Naloxone sensitive orphanin FQ-induced analgesia in mice. Eur. J. Pharmacol. 311: R7-R8, 1996.
33. Sandin, J., J. Georgieva, P. A. Schott, S. O. Ogren, and L. Terenius. Nociceptin/orphanin FQ microinjected into hippocampus impairs spatial learning in rats. Eur. J. Neurosci. 9: 194-197, 1997.
34. Takahashi, T., D. Bagnol, A. Yazdani, Y. Li, S. J. Watson, and C. Owyang. Distribution and actions of orphanin in rat gastrointestinal tract (Abstract). Gastroenterology 114: A845, 1998.
35. Thompson, R. C., A. Mansour, H. Akil, and S. J. Watson. Cloning and pharmacological characterization of a rat μ opioid receptor. Neuron 11: 903-913, 1993.
36. Vaughan, C. W., S. L. Ingram, and M. J. Christie. Actions of the ORL1 receptor ligand nociceptin on membrane properties of rat periaqueductal gray neurons in vitro. J. Neurosci. 17: 996-1003, 1997.
37. Ward, S. J., and A. E. Takemori. Relative involvement of receptor subtypes in opioid-induced inhibition of intestinal motility in mice. Life Sci. 31: 1267-1270, 1982.
38. Weisbrodt, N. W., and P. Bass. In vivo motility techniques. In: Handbook of Methods in Gastrointestinal Pharmacology, edited by T. S. Gaginella. Boca Raton, FL: CRC, 1996, p. 163-187.
39. Yazdani, A., T. Takahashi, D. Bagnol, H. Akil, S. J. Watson, and C. Owyang. A newly discovered neuropeptide, orphanin FQ; its distribution and action in rat gastrointestinal tract (Abstract). Gastroenterology 112: A1201, 1997.
40. Zhang, G., T. F. Murray, and D. K. Grandy. Orphanin FQ has an inhibitory effect on the guinea pig ileum and the mouse vas deferens. Brain Res. 772: 102-106, 1997.