The inhibitory effect of nociceptin on the micturition reflex in anaesthetized rats

British Journal of Pharmacology

Volumn 124, Issue 7, 1998, Pages 1566-1572

  Giuliani, Sandro ^a   Lecci, Alessandro ^a   Tramontana, Manuela ^a   Maggi, Carlo Alberto ^a  

^a Menarini Ricerche ^*  (Italy)

Author keywords

Micturition reflex; Nociceptin; Pelvic stimulation; Urinary bladder

Indexed keywords

ACETYLCHOLINE; CAPSAICIN; GUANETHIDINE; NALOXONE; NEUROPEPTIDE; NOCICEPTIN; URETHAN;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; DOSE RESPONSE; ELECTROSTIMULATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MICTURITION REFLEX; NONHUMAN; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; CAPSAICIN; ELECTRIC STIMULATION; MALE; OPIOID PEPTIDES; RATS; RATS, WISTAR; REFLEX; URINARY BLADDER; URINATION;

EID: 0031827585     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701983     Document Type: Article

References (31)

1. BERZETEI-GURSKE, I.P., SCHWARTZ, R.W. & TOLL, L. (1996). Determination of activity for nociceptin in the mouse vas deferens. Eur. J. Pharmacol., 302, R1-R2.
2. CALÒ, G., RIZZI, A., BOGONI, G., NEUGEBAUER, V., SALVADORI, S.R., GUERRINI, R., BIANCHI, C. & REGOLI, D. (1996). The mouse vas deferens: a pharmacological preparation sensitive to nociceptin. Eur. J. Pharmacol., 311, R3-R5.
3. CARPENTER, F.G. (1986). Micturition in naive and morphine-dependent rats. Br. J. Pharmacol., 87, 725-731.
4. CZAPLA, M.A., CHAMPION, H.C. & KADOWITZ, P.J. (1997). Nociceptin an endogenous ligand for the ORL1 receptor, has vasodilator activity in the hindquarters vascular bed of the rat. Peptides, 18, 793-795.
5. DE GROAT, W.C. & KAWATANI, M. (1989). Enkephalinergic inhibition in parasympathetic ganglia of the urinary bladder of the cat. J. Physiology, 413, 13-29.
6. DRAY, A. & METSCH, R. (1984a). Morphine and the centrally-mediated inhibition of urinary bladder motility in the rat. Brain Res., 297, 191-195.
7. DRAY, A. & METSCH, R. (1984b). Inhibition of urinary bladder contractions by a spinal action of morphine and other opioids. J. Pharmacol. Exp. Ther., 231, 254-260.
8. DRAY, A., NUNAN, L. & WIRE, W. (1985). Central δ-opioid receptor interactions and the inhibition of reflex urinary bladder contractions in the rat. Br. J. Pharmacol., 85, 717-726.
9. GIULIANI, S. & MAGGI, C. A. (1996). Inhibition of tachykinin release from peripheral endings of sensory nerves by nociceptin, a novel opioid peptide. Br. J. Pharmacol., 118, 1567-1569.
10. GIULIANI, S. & MAGGI, C.A. (1997). Prejunctional modulation by nociceptin of CGRP release from capsaicin-sensitive sensory nerves in guinea-pig left atrium. Eur. J. Pharmacol., 332, 231-236.
11. GIULIANI, S., TRAMONTANA, M., LECCI, A. & MAGGI, C.A. (1997). Effect of nociceplin on heart rate and blood pressure in anaesthetized rats. Eur. J. Pharmacol., 333, 177-179.
12. GUMUSEL, B., HAO, Q., HYMAN, A., CHANG, J.K., KAPUSTA, D. R. & LIPPTON, H. (1997). Nociceptin: an endogenous agonist for central opioid like-1 (ORL1) receptors possesses systemic vasorelaxant properties. Life Sci. Pharmacol. Letters, 60, PL141-PL145.
13. HELYES, Z., NEMETH, J., PINTER, E. & SZOLCSÀNYI, J. (1997). Inhibition by nociceptin of neurogenic inflammation and the release of SP and CGRP from sensory nerve terminals. Br. J. pharmacol., 121, 613-615.
14. HENDERSON, G. & MCKNIGHT, A.T. (1997). The orphan opioid receptor and its endogenous ligand - nociceptin/orphanin FQ. Trends Pharmacol. Sci., 18, 293-300.
15. KUMMER, W. & FISCHER, A. (1997). Nociceptin and its receptor in guinea-pig sympathetic ganglia. Neurosci. Letters, 234, 35-38.
16. LECCI, A., GIULIANI, S., MEINI, S. & MAGGI, C.A. (1995). Pharmacological analysis of the local and reflex responses to bradykinin on rat urinary bladder motility in vivo. Br. J. Pharmacol., 114, 708-714.
17. LECCI, A., GIULIANI, S., PATACCHINI, R. & MAGGI, C.A. (1993). Evidence against a peripheral role of tachykinins in the initiation of micturition reflex in rats. J. Pharmacol. Exp. Ther., 264, 1327-1332.
18. MAGGI, C.A. (1991). The role of peptides in the regulation of micturition reflex: an update. Gen. Pharmacol., 22, 1-24.
19. MAGGI, C.A., EVANGELISTA, S., GRIMALDI, G., SANTICIOLI, P., GIOLITTI, A. & MELI, A. (1984a). Evidence for the involvement of arachidonic acid metabolites in spontaneous and drug-induced contractions of the rat urinary bladder. J. Pharmacol. Exp. Ther., 230, 500-513.
20. MAGGI, C.A., FURIO, M., SANTICIOLI, P., CONTE, B. & MELI, A. (1987). The spinal and supraspinal components of GABAergic inhibition of micturition reflex in rats. J. Pharmacol. Exp. Ther., 240,998-1006.
21. MAGGI, C.A., GIULIANI, S. & MELI, A. (1989a). Dermorphin inhibits micturition reflex in rats at a central site of action. J. Auton. Nerv. System, 26, 11-16.
22. MAGGI, C.A., GIULIANI, S., PATACCHINI, R., SANTICIOLI, P., CONTE, B., BARTOLINI, A. & MELI, A. (1989b). Opioid-like action of eseroline on micturition reflex in rats. Gen. Pharmacol., 20, 17-22.
23. MAGGI, C.A., & MELI, A. (1986). The role of neuropeptides in the regulation of the micturition reflex. J. Autonom. Pharmacol., 6, 133-162.
24. MAGGI, C.A., SANTICIOLI, P., BORSINI, F., GIULIANI, S. & MELI, A. (1986). The role of the capsaicin-sensitive innervation of the rat urinary bladder in the activation of micturition reflex. Naunyn-Schmiedeberg's Arch. Pharmacol., 332, 276-283.
25. MAGGI, C.A., SANTICIOLI, P., & MELI, A. (1984b). The effect of topical capsaicin on rat urinary bladder motility in vivo. Eur. J. Pharmacol., 103, 41-40.
26. MAGGI, C.A., SANTICIOLI, P., & MELI, A. (1985a). GABA inhibits excitatory neurotransmission in rat pelvic ganglia. J. Pharm. Pharmacol., 37, 349-351.
27. MAGGI, C.A., SANTICIOLI, P., & MELI, A. (1985b). Pharmacological evidence for the existence of two components in the twitch response to field stimulation of detrusor strips from the rat urinary bladder. J. Auton. Pharmacol., 5, 221-230.
28. 1 receptor. Nature, 377, 532-535.
29. MONTIEL, J.L., CORNILLE, F., ROQUES, B.P. & NOBLE, F. (1997). Nociceptin/orphanin FQ metabolism: role of aminopeptidase and endopeptidase 24.15. J. Neurochemistry. 68, 354-361.
30. PATEL, H.J., GYEMBICZ, M.A., SPICUZZA, L., BARNES, P.J. & BELVISI, M.G. (1997). Naloxone-insensitive inhibition of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by the novel opioid, nociceptin. Br. J. Pharmacol., 120, 735-736.
31. WANG, J.B., JOHNSON, P.S., IMAI, Y., PERSICO, A.M., OZENBERGER, B.A., EPPLER, C.M. & UHL, G.R. (1994). cDNA cloning of an orphan receptor gene family member and its splice variant. FEBS Letters, 348, 75-79.